Membership

Membership and minutes for the Commission on Human Medicines (CHM) and its expert advisory groups (EAGs).

Working for us

In the public interest, ministers need the advice they receive on matters relating to the regulation of medicines and medical devices to be impartial. They also need to be able to get advice from a wide range of highly-skilled professionals who are senior and well regarded in their respective fields and from a range of appointed lay representatives.

A number of independent advisory committees have been established to provide this advice. These committees can also establish working groups to address specific problems. Members of these committees may receive a fee and can claim some expenses.

If you are interested in being part of the Commission on Human Medicines or one of its expert advisory groups please contact cstrecruitment@mhra.gov.uk.

The chair and commissioners are appointed in accordance with the Code of Practice for Ministerial Appointments to Public Bodies, issued by the Commissioner for Public Appointments. The chair and commissioners follow a code of practice, in which they are precluded from holding personal interests. Their interests in the pharmaceutical industry are published in the commission’s annual report each year.

The commission meets monthly in London. The commission is supported in its work by expert advisory groups (EAGs), covering various areas of medicine. In addition, the commission calls on experts not readily available through its membership.

Current vacancies

The CHM Expert Advisory Group is looking to appoint one expert member to the Oncology and Haematology Expert Advisory Group (OHEAG) in the following area:

  • Haematologist with expertise in haematological oncology

Please find attached:

The closing date for applications is midday Monday 25 November 2024.

The CHM Expert Advisory Group is looking to looking to appoint an expert to the Neurology, Pain and Psychiatry Expert Advisory Group (NPP EAG) in the following area;

  • Neurology and dementia

Please find attached:

The closing date for applications is 18th November 2024.

The CHM Expert Advisory Group is looking to appoint two experts to the Chemistry, Pharmacy and Standards Expert Advisory Group (CPS EAG).

  • Candidates should be recognised by their peers in one or more of the following areas:
  • Formulation of medicinal products, manufacturing methods including application of the principles of Quality by Design and analytical control during manufacture and throughout shelf life.
  • Innovative medicines
  • Development of medicines for special populations including but not limited to paediatrics.
  • Medicinal Organic Chemistry encompassing drug substance design, synthesis and characterisation.
  • Pharmaceutical analysis - analytical method design, validation and applications.

Please find attached:

The closing date for applications is midday 04 November 2024.

The CHM Expert Advisory Group is looking to appoint one expert to the Clinical Trials, Biologicals and Vaccines Expert Advisory Group (CTBV EAG).  Expertise required for the role in the following area:

  • Vaccination and immunisations specialist

Please find attached:

The closing date for applications is midday 4 November 2024.

The CHM Expert Advisory Group is looking to appoint one expert member to the Paediatric Medicines Expert Advisory Group (PMEAG) in the following area:

  • General Practitioner

Please find attached:

The closing date for applications is Monday 28 October 2024.

CHM chair and commissioners

(Chair) Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FBPhS, FFPM (Hon) FMedSci, David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Director of the Wolfson Centre for Personalised Medicine, Director of the Centre for Drug Safety Science

Professor Amanda Adler MD PhD FRCP Professor of Diabetic Medicine and Health Policy, University of Oxford

Professor Jamie Coleman MD MA (Med Ed) FRCP FBPhS Professor in Medical Education / Consultant Clinical Pharmacologist, University of Birmingham

Professor Steven Cunningham MBChB PhD FRCPCH Professor of Paediatric Respiratory Medicine, University of Edinburgh and Honorary Consultant, Royal Hospital for Children and Young People, NHS Lothian, Edinburgh

Dr Jamie Fraser BSc (Hons) MBChB MRCGP GP Partner, Southside Surgery, Inverness

Professor Sandosh Padmanabhan MBBS MD PhD FRCP(Glasg) FRCP(Edin) FBPhS FBIHS Professor of Cardiovascular Genomics and Therapeutics, University of Glasgow

Professor Poulam Patel PhD, MBBS, FRCP Professor of Clinical Oncology, University of Nottingham

Professor Yvonne Perrie BSc Hons MRPharmS FAPS FSB PhD Chair in Drug Delivery, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow. Scotland

Professor Marc Turner MBChB PhD MBA FRCP FRCPath FRSE Professor of Cellular Therapy; Director Scottish National Blood Transfusion Service (SNBTS)

Professor Christopher Weir BSc (Hons) PhD MSc FRSS C.Stat
Personal Chair in Medical Statistics and Clinical Trials, Usher Institute, University of Edinburgh

Dr Martin Wilson MRCP (UK) MPhil (Glasgow), FRCP(Edin) Consultant Physician in Care of the Elderly, Raigmore Hospital, Inverness

Mrs Julia Cons Lay Representative

Professor Paul I Dargan MB BS FRCP Edin FACMT FRCP ERT FAACT FEAPCCT FBPhS MAE Consultant Physician and Professor of Clinical Toxicology, Guy’s and St Thomas’ NHS Foundation Trust, London Professor of Clinical Toxicology, King’s College London

Professor David Dockrell MB BCh MD FRCPI FRCP (Glas) FACP Professor of Infection Medicine, University of Edinburgh

Professor David Hunt MB BChir FRCP PhD Consultant Neurologist, NHS Lothian, Professor of Neuroinflammatory Medicine, University of Edinburgh

Dr Gerri Mortimore PhD; MSc Advanced Practice; PgCert (IPPE); Ba(Hons) Health Studies; iLM. RGN; NMP; FHEA Associate Professor in Advanced Clinical Practice; NICE Nurse Expert Advisor

Professor Vanessa Raymont MBChB MSc MRCPsych Associate Professor, University of Oxford and Honorary Consultant Psychiatrist, Oxford Health NHS Foundation Trust

Professor Anthony Williams BSc MSc MRCP, FRCPath, PhD Professor  of Translational Medicine and Honorary Consultant in Clinical Immunology and Allergy, University of Southampton and University Hospital Southampton NHS Trust

Professor Rui Providencia MD PhD Consultant Cardiologist & Cardiac Electrophysiologist, Barts Health NHS Trust Institute of Health Informatics Research, University College London

Professor Heather M Wallace PhD FRCPath FRSC FRSB FBTS FBPhS ERT Professor Emeritus of Biochemical Pharmacology and Toxicology, University of Aberdeen

Professor David Moore MBChB MD MSc DTM&H Professor of Infectious Diseases and Tropical Medicine, London School of Hygiene and Tropical Medicine and Consultant in Infectious Diseases and Tropical Medicine, Hospital for Tropical Diseases, University College London Hospital

Mr David Crundwell Lay Representative

Summary minutes

Summary minutes are prepared on the basis that no personal, commercial or otherwise confidential information is disclosed.

See the final summary minutes for CHM and EAGs from 2014 onwards, which you can download.

Previous minutes can be seen on the MHRA pages on the National Archives.

CHM meeting dates

2023

Jan Feb March April May June July Aug Sept Oct Nov Dec
26/27 23/24 23/24 27/28 25/26 29/30 27/28 24/25 28/29 26/27 23/24 21/22

2024

Jan Feb March April May June July Aug Sept Oct Nov Dec
25/26 22/23 21/22 25/26 30/31 27/28 25/26 29/30 26/27 24/25 21/22 19/20

2025

Jan Feb March April May June July Aug Sept Oct Nov Dec
23/24 27/28 27/28 24/25 29/30 26/27 24/25 28/29 25/26 30/31 27/28 18/19

Infection EAG

Remit

To advise the Commission on the safety and efficacy of medicines for use in infections including HIV, AIDS and viral hepatitis.

Chair

Professor David Dockrell MB BCh MD FRCPI FRCP (Glas) FACP Professor of Infection Medicine, University of Edinburgh

Members

Professor Brian Angus BSc MBChB MA (Oxon) DTM&H FRCP FFTM                                                                                      
Reader in Infectious Diseases, University of Oxford

Dr Michael Brown BA BM BCh FRCP PhD DTM&H Consultant Physician, Infectious Diseases & Acute Medicine, & Clinical Director, Division of Infection, University College London Hospitals NHS Foundation Trust & Honorary Associate Professor, Clinical Research Sept, London School of Hygiene & Tropical Medicine

Dr Andrew Freedman B.A M.B,B.Chir M.A M.D FRCP FRCP Reader in Infectious Diseases, Cardiff University School of Medicine/ Hon. Consultant Physician, University Hospital of Wales

Professor Richard J C Gilson MD FRCP Professor of Sexual Health & HIV Medicine, Director of the UCL Centre for Clinical Research in Infection Sexual Health & Deputy Director of the UCL Institute for Global Health

Dr Richard Hobson MB BS MRCP (UK) FRCPath PhD LLM Consultant Microbiologist and Honorary Senior Lecturer, Harrogate & District NHS Foundation Trust/University of Leeds

Dr Lim S Jones MBBCh, PhD, FRCPath Consultant Microbiologist, Public Health Wales Microbiology, Cardiff; Clinical Lead Specialist Antimicrobial Chemotherapy Unit, Cardiff; Chair of the All Wales Medical Microbiology Development & Standardisation Group

Dr Matthias Schmid MD FRCP DTMH Consultant Physician, Head of Department of Infection & Tropical Medicine, Director of Elective Studies Newcastle University, Royal Victoria Infirmary, Newcastle upon Tyne

Professor Geraint Rhys Davies BM DTM&H PhD FRCP Professor of Infection Pharmacology, University of Liverpool, Honorary Consultant in Infectious Diseases, Liverpool University Hospitals Foundation Trust

Dr Louis Grandjean MBBS BSc MSc PhD MRCPCH Associate Professor Paediatric Infectious Diseases Great Ormond Street Hospital and University College London

Mrs Stella O’Brien MA (Hons) Lay Member

Cardiovascular, Diabetes, Renal, Respiratory and Allergy EAG

Remit

To advise CHM on the safety and efficacy of medicines for used for the treatment and prevention of cardiovascular, diabetes, renal, respiratory and allergy diseases.

Chair

Professor Amanda Adler MD PhD FRCP Professor of Diabetic Medicine and Health Policy, University of Oxford

Members

Professor Sandosh Padmanabhan MBBS MD PhD FRCP(Glasg) FRCP(Edin) FBPhS FBIHS Professor of Cardiovascular Genomics and Therapeutics, University of Glasgow

Professor Patrick Mark MB CHB (Hons) PhD FRCP (Glasg) Professor of Nephrology & Honorary Consultant Nephrologist, University of Glasgow and Glasgow Renal and Transplant Unit, Queen Elizabeth University Hospital, Glasgow

Professor Theresa McDonagh BSc (Hons), MB ChB (Hons), MD (Distinction), FRCP, FESC, FHFA Consultant Cardiologist, King’s College Hospital, London & Professor of Heart Failure King’s College, London

Dr Patrick Holmes MB BS MSc MRCGP GP Partner, St. George’s Medical Practice, Darlington

Professor Anita K Simonds MD FRCP FERS Professor Emeritus of Respiratory and Sleep Medicine, National Heart and Lung Institute, Imperial College, London & Honorary Consultant Respiratory and Sleep Physician, Royal Brompton & Harefield Hospital, Sydney Street, London

Professor William G. Herrington MA(Cantab) MBBS(London) MD(Cantab) FRCP(London) Professor of Trials and Epidemiology of Kidney Disease. Medical Research Council-Population Health Research Unit at the University of Oxford; Honorary Consultant Nephrologist, Oxford Kidney Unit

Dr Wajid Hussain BSc (Hons) MB ChB (Hons) MSc FRCP Consultant Cardiologist, Royal Brompton and Harefield Hospitals, Part of Guys and St Thomas’ NHS Foundation Trust

Dr Amine Boualem MD MRCGP PGDip(Diabetes) AHEA GP Partner, East Barnwell Health Centre, Cambridge

Professor Michael Steiner MB BS BSc MD FRCP Professor in Respiratory Medicine and Honorary Consultant, Dept of Respiratory Science, University of Leicester

Professor Mark Evans BSc MB BS MD FRCP Professor of Diabetic Medicine, University of Cambridge and Consultant Physician, Cambridge University Hospitals

Dr Shuaib Nasser MA MBBS MD FRCP Consultant Allergist and Respiratory Physician, Head of Allergy Cambridge University Hospital NHS Foundation Trust, Cambridge

Meeting dates

2024

Jan Mar April June Sept Nov
15 12 17 19 20 11

2025

Jan Mar May July Sept Nov
16 13 15 16 15 21

Chemistry, Pharmacy and Standards EAG

Remit

To advise the CHM on the quality in relation to safety and efficacy of medicinal products which are the subject of marketing authorisation applications and to advise on such other matters as are referred to it.

Chair

Professor Yvonne Perrie BSc Hons MRPharmS FAPS FSB PhD Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde.

Members

Professor Hannah Batchelor BSc PhD Professor of Pharmaceutics and Biopharmaceutics, Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathclyde

Professor Barbara R Conway BSc (Pharm) PhD FRPharmS CMgr FCMI Head of Pharmacy and Professor of Pharmaceutics, University of Huddersfield, Huddersfield

Dr Majella Lane BSc PhD – (Vice Chair) Senior Lecturer in Pharmaceutics, UCL School of Pharmacy

Professor Afzal R Mohammed BPharm PhD Professor of Pharmaceutics, Aston Pharmacy School, Aston University

Mrs Ruth Paulin BPharm MRPharmS Practising Community Pharmacist.

Professor Darragh Murnane PhD BSc (Pharm) PhD MRPharmS Professor of Pharmaceutics and Associate Dean (Enterprise), University of Hertfordshire

Professor Susannah E Walsh PhD BSc MBA Head of School, Professor of Pharmaceutical Microbiology, Pharmacy and Life Sciences, Robert Gordon University

Professor Ben Forbes BPharm PhD Professor of Pharmaceutics, Institute of Pharmaceutical Science, Kings College London

Mr Hadar Zaman MPharm, MFRPSII, IPresc, FHEA Associate Professor in Pharmacy Practice and Head of School for Pharmacy and Medical Sciences, University of Bradford, , Associated Non-Executive Director Barnsley Hospital

Mr Robert Lowe BPharm FRPharmS Practising Hospital Pharmacist, Specialist Pharmacy Services - East of England

Professor Luigi (Gino) Martini BSc (Hons), PhD, MBA, FRPharmS, FRSC Chief Executive Precision Health Technology Accelerator (PHTA), University of Birmingham Honorary Professor in Pharmacy, University of Birmingham

Dr Federico Brucoli Pharm. D. PhD CChem MRSC mGPhC FHEA Senior Lecturer in Medicinal Chemistry, Leicester School of Pharmacy, De Montfort University, Leicester

Professor Nikoletta Fotaki Pharmacy Degree (Ptychion) MSc PhD Professor of Biopharmaceutics, Centre for Therapeutic Innovation and Department of Life Sciences, University of Bath

Meeting dates

2024

Oct Nov Dec
22 19 17

2025

Jan Feb March Apr May June Jul Aug Sept Oct Nov Dec
- 25 25 22 27 24 tbc tbc tbc tbc tbc tbc

Clinical Trials, Biologicals and Vaccines EAG

Remit

To advise the CHM on:

  • first time in human (FTIM) studies with new compounds acting (directly or indirectly) via the immune system with a novel target or a novel mechanism of action or having a secondary potential effect on the immune system via a mechanism of action which currently is not well characterised
  • FTIM studies with novel compounds acting via a possible or likely species specific mechanism
  • any FTIM studies which are otherwise seen as requiring expert advice
  • other clinical trials involving classes of compound where MHRA may wish to seek external expert advice or CHM may wish to have oversight
  • whether a product’s mechanism of action is novel and comes within the scope of the EAG
  • pre-meeting scientific advice documentation for within scope compounds
  • other clinical trials where MHRA may wish to seek advice or where there is a difficult risk benefit balance
  • other clinical trials involving products where a new class safety issue has been identified
  • the quality, safety and efficacy of medicinal products of biological or biotechnological origin including vaccines which are the subject of marketing authorisation applications; and to advise on such other matters as are referred to it

Chair

Professor Marc Turner MB ChB PhD MBA FRCP FRCPath FRSE Professor of Cellular Therapy; Director Scottish National Blood Transfusion Service (SNBTS)

Members

Professor Farzin Farzaneh DPhil FRCPath FRSB, Professor of Molecular Medicine, King’s College London, Honorary Consultant in Specialist Medicine, King’s College Hospital NHS Trust

Professor Chris Goldring BSc PhD PGCert FBPhS, Professor of Pharmacology, Department of Pharmacology and Therapeutics, The University of Liverpool.

Dr Robin Thorpe PhD FRCPath Retired, Head, Division of Biotherapeutics, National Institute for Biological Standards and Control (NIBSC)

Dr Kirstie Shearman LLB MA PhD (Lay member) Policy Manager, Health Research Authority

Meeting dates

2023

Jan Feb Mar Apr May June July Aug Sept Oct Nov Dec
23 20 20 24 22 26 24 21 25 23 20 18

2024

Jan Feb Mar Apr May June July Aug Sept Oct Nov Dec
19 20 19 23 28 25 23 27 24 22 19 17

Gastroenterology, Rheumatology, Immunology and Dermatology EAG

Remit

To advise the CHM on the safety and efficacy of medicines for use in gastroenterological, rheumatological, immunological, and dermatological diseases.

Chair

Professor Anthony Williams BSc MSc MRCP, FRCPath, PhD Professor  of Translational Medicine and Honorary Consultant in Clinical Immunology and Allergy, University of Southampton and University Hospital Southampton NHS Trust

Members

Professor Anjan Dhar DM, MD (Medicine), FRCPE, AGAF, Cert. Med. Ed, FHEA Professor of Medicine (Teesside University), Consultant Gastroenterologist, Clinical Lead for UGI Cancers, County Durham & Darlington NHS Foundation Trust

Dr Shahida Din BMSc, MBChB, PhD, FRCP (Edin) Consultant Gastroenterologist & NHS Research Scotland Clinician, NHS Lothian; Honorary Senior Clinical Lecturer, University of Edinburgh.

Professor Michael Ardern-Jones BSc MBBS DPhil FRCP Associate Professor, University of Southampton and Consultant Dermatologist

Professor Celia Moss OBE BA(Hons) MB BS MA MRCP DM FRCP MRCPCH Honorary Consultant Dermatologist, Birmingham Women’s and Children’s NHS FT, Honorary Professor of Paediatric Dermatology, University of Birmingham

Mr James Pitayanukul BSc (Hons) MSc CA Lay Member

Professor Nidhi Sofat PhD MBBS FRCP PGCert FHEA Professor of Rheumatology, St Georges University London

Dr Ravishankar Sargur MD, FRCPath, FRCP, MBA Consultant Clinical Immunologist and Clinical Lead for Laboratory Immunology, Northern General Hospital, Sheffield

Professor Stuart Ralston MB ChB MD FRCP FMedSci FRSE FFPM (Hon) Professor of Rheumatology, University of Edinburgh, Western General Hospital, Edinburgh

Meeting dates

2024

Jan Feb Mar Apr May Jun Jul Sep Oct Nov Dec
16 14 15 17 17 14 17 3 16 12 13

Medicines for Women’s Health EAG

Remit

To advise the CHM on the safety and efficacy of medicines related to endocrinology and women’s reproductive health from menarche to menopause and conditions related to the menopause, such as osteoporosis. The medicines covered will include medicines for contraception, emergency contraception and termination of pregnancy; medicines for infertility and assisted conception; hormone replacement therapy (HRT) and non-hormonal treatments for osteoporosis.

Chair

Professor Philip Hannaford MBChB, MD, FRCGP, FFPH, FFSRH, FRSE Emeritus Professor of Primary Care, University of Aberdeen

Members

Dr Caitlin Dean RGN, MSc, PhD (Lay member) Chair Trustee, Pregnancy Sickness Support

Dr Kenneth Hodson MD MBChB MRCP(UK) MRCOG Head of UK Teratology Information Service UK Teratology Information Service

Dr Asha Kasliwal FRCOG FFRSH FRCGP (Hon) FFPH (Hon)
Consultant in Community Gynaecology and Reproductive Health, Manchester University NHS Foundation Trust Hathersage Centre

Dr Jonathan Lord MD FRCOG FHEA
Consultant Obstetrician and Gynaecologist, Royal Cornwall Hospitals NHS Trust

Dr Louise Massey MBChB FFSRH FFPH
Consultant in Sexual and Reproductive Health Aneurin Bevan University Health Board

Ms Linda Pepper BA MA (Education) - (Lay member) Independent Consultant: patient and public involvement in healthcare

Dr Julia Prague MBBS PhD MRCP(UK) BSc Consultant in Endocrinology, Diabetes, and General Internal Medicine, Royal Devon and Exeter NHS Foundation Trust, and Honorary Senior Clinical Lecturer, College of Medicine and Health, University of Exeter

Professor Stuart Ralston MB ChB MD FRCP FMedSci FRSE FFPM (Hon) Professor of Rheumatology, University of Edinburgh, Western General Hospital, Edinburgh

Professor Laurie Tomlinson MBBS MSc PhD NIHR research Professor, Faculty of Epidemiology and Population Health London School of Hygiene & Tropical Medicine

Dr Diana Wellesley FRCP (Vice Chair) Honorary Consultant and Honorary Senior Lecturer in Clinical Genetics, Wessex Clinical Genetics Service, Princess Anne Hospital Southampton

Meeting dates

Feb Jun Jul Sep Oct Dec
27 19 15 5 9 11

Neurology, Pain and Psychiatry EAG

Remit

To advise the CHM on the safety and efficacy of medicines for use in neurological conditions, pain management and psychiatric conditions.

Chair

Professor David Hunt MB BChir FRCP PhD Consultant Neurologist, NHS Lothian, Professor of Neuroinflammatory Medicine, University of Edinburgh

Members

Dr Lisa Brownell BSc(Hons) MBChB PGCertMedEd FHEA FRCPsych Associate Medical Director, Birmingham and Solihull Mental Health NHS Foundation Trust Chair of Area Prescribing Committee, Birmingham, Sandwell, Solihull and Environs

Professor Naomi Fineberg BA Hons MB BS MA MRCPsych Consultant in General Adult Psychiatry, Hertfordshire Partnership NHS

Dr Barry Mark Miller MB ChB FRCA FFPMRCA Consultant in Pain Medicine and Anaesthesia, Bolton NHS Foundation Trust. Board Member of the Faculty of Pain Medicine.

Professor David G C Owens MD (Hons) FRCP FRCPsych Professor of Clinical Psychiatry, Edinburgh University

Dr Waqar Rashid MBBS BSc MRCP(UK) PhD Consultant and Honorary Clinical Senior Lecturer in Neurology, Brighton and Sussex University Hospitals NHS Trust, member of the Multiple Sclerosis Society

Dr Fergus Rugg-Gunn MB BS MRCP PhD Consultant Neurologist, National Hospital for Neurology and Neurosurgery, Queen Square, London

Dr Aditya Sharma MBBS MD MRCPsych PhD Clinical Senior Lecturer and Honorary Consultant in Child and Adolescent Psychiatry at Newcastle University and Cumbria, Northumberland Tyne and Wear NHS Foundation Trust

Dr Hoo Kee Tsang BSc(Hons) MB BCh FRCA FFPMRCA Consultant in Pain Medicine and Anaesthesia, Clinical Director of Pain Services, Liverpool University Hospitals NHS Foundation Trust, member of the Royal College of Anaesthetists and the Faculty of Pain Medicine training and assessment committees.

Meeting dates 2024

Jan March June Sept Oct Dec
10th 6th 12th 18th 17th 4th

Oncology and Haematology EAG

Remit

To advise the CHM on the safety, quality and efficacy of medicines used in the treatment of malignant disease or blood disorders.

Chair

Professor Poulam Patel PhD, MBBS, FRCP Professor of Clinical Oncology, University of Nottingham

Members

Professor Janet E Brown FRCP, MD,MSc, BMedSci, MBBS Academic Unit of Clinical Oncology, Department of Oncology and Metabolism, Weston Park Hospital, University of Sheffield.

Dr Rebecca Kristeleit BSc MBChB PhD FRCP FRSB Consultant Medical Oncologist, Guy’s and St Thomas’ NHS Foundation Trust.

Dr Perminder Tony Singh Dhillon Bsc, MB BS, FRCP, PhD
Consultant Medical Oncologist, Royal Surrey Hospital, Guildford, Surrey and Hon. Senior Lecturer in Oncology, University of Surrey

Professor Siow Ming Lee PhD FRCP Professor of Medical Oncology, Consultant Medical Oncologist

Dr Debashis Sarker MBChB PhD FRCP Reader in Experimental Oncology, King’s College London Consultant Medical Oncologist, Guy’s, St Thomas’ and King’s College Hospitals

Professor James Spicer FRCP, PhD Professor of Experimental Cancer Medicine, King’s College London; Consultant in Medical Oncology, Guy’s & St Thomas’ NHS Foundation trust Vice Chair

Dr Ben Uttenthal MA MB BS PhD MRCP FRCPath Consultant Haematologist, Cambridge University Hospitals

Dr Anjum Khan PhD MBChB FRCPath MRCP
Consultant Haematologist, Leeds Teaching Hospitals NHS Trust.

Meeting dates 2023

July Aug Sept Oct Nov Dec
25 17 21 19 16 14

Meeting dates 2024

Jan Feb March Apr May June July Aug Sept Oct Nov Dec
11th 15th 14th 18th 23rd 20th 18th 22nd 19th 17th 14th 12th

Paediatric Medicines EAG

The remit of the EAG is to advise the CHM on the safety, quality and efficacy of medicines for paediatric use, including all matters relating to the implementation of the EU Paediatric Regulation.

Chair

Professor Steven Cunningham MBChB PhD FRCPCH Professor of Paediatric Respiratory Medicine, University of Edinburgh and Honorary Consultant, Royal Hospital for Children and Young People, NHS Lothian, Edinburgh

Members

Mrs Catrin Barker, Chief Pharmacist, Pharmacy Department, Alder Hey Children’s NHS FT, Eaton Road, Liverpool

Dr Simon B Drysdale BSc (Hons), MBBS, FRCPCH, PhD, PgDip PID (Oxford), FHEA Senior Lecturer, Oxford Vaccine Group, University of Oxford, Consultant in Paediatric Infectious Diseases and Immunology, Children’s Hospital, Oxford

Dr Daniel Hawcutt BSc (Hons), MB ChB (Hons), MD, MRCPCH, Senior Lecturer Paediatric Clinical Pharmacology, Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool

Dr Kathryn Johnson MBChB FRCPCH, Consultant Neonatologist, Leeds Teaching Hospitals NHS Trust and Honorary Senior Lecturer, Leeds University Vice Chair

Dr Caroline Jones MB ChB FRCPCH MD, Consultant Paediatric Nephrologist, Alder Hey Children’s NHS Foundation Trust

Dr Daniel E Lumsden MB/BChir MA Cantab MSc PhD FRCPCH, Consultant Paediatric Neurologist, Evelina London Children’s Hospital, Adjunct Clinical Senior Lecturer, Department of Perinatal Imaging, King’s College London

Dr Jacqueline McMurtrie BSc (Hons), MSc, PhD Lay Representative

Dr Clare Pain BMBS, MSc, MRPCH, Consultant Paediatric Rheumatologist, Clinical Lead for Rheumatology Honorary Clinical Lecturer, University of Liverpool Co-Chair of NIHR CRN: children/Versus Arthritis Paediatric Rheumatology Clinical Studies Group Associate Director, UK Experimental Arthritis Treatment Centre for Children (Behcet’s and scleroderma workstreams)

Dr Guido Pieles PhD MD, Consultant Congenital Cardiologist, Congenital Hear Unit, Bristol Heart Institute

Professor Shirley Price MSc, PhD, FBTS, FRSB, ERT, FHEA,FRSC, MBPharmacolSoc, Emerita Professor of Toxicology, University of Surrey Visiting Professor of Toxicology, University of Hertfordshire

Mrs Julia Taylor MSc BSc, Paediatric Advanced Nurse Practitioner, High Dependency Unit, Alder Hey Children’s NHS Foundation Trust

Mrs Rhian Thomas-Turner LLM, PG Dip Legal Practice Lay Representative. Research and Development Lead, Noah’s Ark Children’s
Hospital for Wales, Cardiff and Vale University Health Board

Dr William John Watkins BSc PhD, Senior Statistician/Lecturer, College of Biomedical & Life Sciences, Cardiff University

Dr Martin William English BMSc, MBChB, MD, FRCP(Glas), FRCPCH, Consultant Paediatric Oncologist, Birmingham Women’s and Children’s Hospital NHS Foundation Trust

M Dr Ashley Liew MBChB, MRCPsych, MSc. Consultant Paediatric Neuropsychiatrist, Evelina London Children’s Hospital and South London & Maudsley NHS Foundation Trust.  Honorary Senior Research Fellow, University of Warwick.

Meeting dates

2023

Jan Feb March Apr May June July Aug Sept Oct Nov Dec
18 15 15 19 17 21 19 16 20 18 15 13

Meeting dates

2024

Jan Feb March Apr May June July Aug Sept Oct Nov Dec
10 13 13 10 15 18 10 21 17 9 6 3  

Pharmacovigilance EAG

PEAG now review applications for access to Type II Yellow Card data, the completed application form should be emailed directly to vigilanceservice@mhra.gov.uk.

Remit

To advise the CHM on the following in relation to human medicines including herbal products:

  • the public health importance of potential new signals
  • the confirmation and quantification of risks identified
  • appropriate risk minimisation measures including communications
  • design and progress of pharmacovigilance plans
  • methodologies for pharmacovigilance.

Chair

Professor Jamie Coleman MD MA (Med Ed) FRCP FBPhS Professor in Medical Education/Consultant Clinical Pharmacologist, University of Birmingham

Members

Dr Anna Schultze BSc MSc PhD
Assistant Professor in Pharmacoepidemiology, Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine

Professor Darren Ashcroft BPharm MSc PhD FRPharmS Professor of Pharmacoepidemiology, Division of Pharmacy and Optometry, Manchester University

Professor Ann Daly BA PhD FBPhS Professor of Pharmacogenetics, Faculty of Medical Sciences, Newcastle University

Dr Dan Hawcutt BSc MB ChB MD MRCPCH Senior Lecturer in Paediatric Clinical Pharmacology, Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool.

Dr Malcolm Oswald, Lay Member
Honorary Research Fellow in Law, University of Manchester

Professor Rupert Payne MB ChB PhD MRCGP FRCPE FBPhS FHEA Professor of Primary Care & Clinical Pharmacology, University of Exeter

Ms Susan Hunneyball BSc (Hons) Lay Member

Mrs Alana Adams BPharm (Hons), MSc, IP, MRPharmS
Principal Pharmacist Medicines Information, advice and Safety, University of Cardiff

Dr Richard FitzGerald MD MBChB PhD FRC
CRF Director, NIHR Royal Liverpool and Broadgreen CRF

Professor Patricia McGettigan MD, BSc, MB, BCh, BAO, BA
Professor in Clinical Pharmacology and Medical Education and Consultant Physician, Barts Health Trust

Professor Reecha Sofat MBBS, FRCP, PhD Breckenridge Chair of Clinical Pharmacology and Therapeutics, University of Liverpool

Dr Fraz Arif Mir MA FRCP Consultant Physician, Cambridge University Hospitals NHS Foundation Trust

Dr Nashat Qamar MB ChB MRCGP MSc DRCOG BSc (hons) 
PCN Clinical Director and GP Partner, Hall Green Health, Birmingham

Meeting dates

2023

Jan Feb March Apr May June July Aug Sept Oct Nov Dec
18 15 14 20 17 22 19 16 20 18 15 13

2024

Jan Feb March Apr May June July Aug Sept Oct Nov Dec
17 15 14 17 23 20 17 22 19 17 14 12

Type II Yellow Card data

PEAG now review applications for access to Type II Yellow Card data. The completed Type II Yellow Card data application form should be emailed directly to vigilanceservice@mhra.gov.uk.

NPP24-1 Advert - Neurology, Pain and Psychiatry Expert Advisory Group (PDF, 132 KB, 2 pages)

Application Form (PDF, 154 KB, 9 pages)

Isotretinoin Expert Working Group

Terms of reference

The terms of reference for the IEWG are:

  • to evaluate information from all available sources, including relevant stakeholders (patients, patient representatives, healthcare professionals, healthcare organisations, researchers, charity and patient organisations) on psychiatric effects suspected to be associated with isotretinoin. To consider whether regulatory action is required to minimise risk and ensure awareness of the risks
  • to evaluate information from all available sources, including relevant stakeholders (patients, patient representatives, healthcare professionals, healthcare organisations, researchers, charity and patient organisations) on sexual disorders suspected to be associated with isotretinoin. To consider whether regulatory action is required to minimise risk and ensure awareness of the risks.
  • to consider the impact of the available information on psychiatric effects and sexual disorders on the balance of benefits and risks of isotretinoin.
  • to consider what research could be undertaken to further elucidate any risks and long-term impact of psychiatric effects and sexual disorders and inform risk minimisation measures.
  • to make recommendations to the Commission on Human Medicines to improve the balance of benefits and risks for isotretinoin, to raise awareness of the associated risks and for further research to evaluate the risks.

Chair

Professor Angela Thomas OBE MB BS PhD FRCPE FRC Path
University of Edinburgh

Members

Professor Darren Ashcroft BPharm, MSc, PhD, FRPharmS Professor of Pharmacoepidemiology, Head, Drug Usage and Pharmacy Practice Group, University of Manchester

Professor Amanda Drake FRCPE Personal Chair of Epigenetics and Metabolism, Academic Director, Academic Foundation Programme, Associate Director, Edinburgh Clinical Academic Training Programme

Professor Nicol Ferrier BSc MB ChB MD FRCP FRCPsych Professor of Psychiatry and Honorary Consultant Psychiatrist, University of Newcastle

Dr Arianna Di Florio Clinical Senior Lecturer, Cardiff University Honorary Consultant Psychiatrist, Cardiff and Vale University Health Board, Adjunct Assistant Professor, University of North Carolina at Chapel Hill

Dr Clive Grattan BA MA MB BChir FRCP MD ILT Consultant Dermatologist, St John’s Institute of Dermatology, Guy’s Hospital, London

Professor David Gunnell MB ChB MRCGP PhD MSc FFPHM Professor of Epidemiology, University of Bristol

Professor Peter C Hindmarsh Professor of Paediatric Endocrinology, University College London

Dr Karen Miller BSc MBBS DRCOG DCH DFFP FRCGP
GP Partner, Adelaide Medical Centre, London

Professor Rod Mitchell Professor of Developmental Endocrinology, Honorary Consultant Paediatric Endocrinologist, UKRI Future Leaders Fellow/Academic Lead for Public Engagement MRC Centre for Reproductive Health, Queens Medical Research Institute, Edinburgh

Professor Gudrun Moore Professor of Clinical and Molecular Genetics, Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health

Mr Giangiacomo Ollandini FRCS MD Milton Keynes Hospital NHS Foundation Trust - Urology Urologist, Andrologist, MSc in andrological surgery and gender disorder

Ms Linda Pepper BA MA (Education) Independent Consultant: patient and public involvement in healthcare

Dr Amr Abdel Raheem MB BCh, MSc, DipSurg, PhD, FECSM, FEAA University College London Hospitals NHS Foundation Trust infertility & contraception, Peyronies Disease, Erectile Dysfunction and male Hypogonadism

Mrs Madeleine Wang BA (Hons) Lay Representative, Patient Advocate

Professor Allan Young Vice Dean, Academic Psychiatry (Interim), Director, Centre for Affective Disorders NIHR Senior Investigator, Academic Director, Psychological Medicine and Older Adults Clinical Academic Group, Immediate Past President of International Society for Affective Disorders, President British Association for Psychopharmacology, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King’s College London

Observers

National Institute for Health and Care Excellence (NICE)

NHS Improvement

The Care Quality Commission

Primary Care Dermatology Society (PCDS)

COVID-19 Therapeutics Expert Working Group

Remit

  • To advise on the safety and efficacy of candidate anti-viral agents, immune-based therapies and repurposed agents for the treatment and prevention of COVID-19 infection, based on available scientific data.
  • To review the robustness of the evidence of supporting agents used for the treatment of COVID-19 complications, including agents based on putative mechanisms, as currently available and based on emerging data.
  • To advise on strategies and study designs to collect efficacy and safety data including novel trial designs.
  • To advise on measures to minimise risks and optimise the benefit-risk balance of anti-viral agents, supportive therapies (e.g., corticosteroids, NSAIDS, chloroquine, immune modulators, etc) proposed for the treatment of COVID-19 infection and its complications.
  • To advise on the benefits and risk of concomitant medications (e.g., ACE inhibitors/ AT-II blockers or immunosuppressants).
  • To advise on measures to monitor safety and effectiveness of risk minimisation measures relating to these medicinal products.
  • To advise the Commission on Human Medicines.

Chair

Professor Jonathan S Friedland MA PhD FRCP FRCPE FRCPI FESCMID FMedSci Deputy Principal, St. George’s, University of London

Members

Professor Kenneth Baillie BSc(Hons) MBChB PhD FRCA FRCP FFICM
Professor of Experimental Medicine Roslin Institute, University of Edinburgh

Ms Susan Bradford Lay Representative

Professor David Dockrell MB BCh MD FRCPI FRCP (Glas) FACP Professor of Infection Medicine, University of Edinburgh

Professor Richard J C Gilson MD FRCP Professor of Sexual Health & HIV Medicine, Director of the UCL Centre for Clinical Research in Infection & Sexual Health & Deputy Director of the UCL Institute for Global Health

Sir Michael Jacobs Consultant & Hon. Senior Lecturer in Infectious Diseases Royal Free London NHS Foundation Trust

Professor Nigel Klein BSc MBBS MRCP PhD FRCPCH Consultant, Great Ormond Street Hospital for Children NHS Trust; Professor of Infectious Diseases and Microbiology, Institute of Child Health, UCL

Dr Siraj Misbah MBBS (Hons) MSc FRCP FRCPath - Consultant Clinical Immunologist, Lead for Clinical Immunology, Oxford University Hospitals

Professor B Kevin Park BSc PhD FMedSci HonFRCP FBTS HonFBPhs Professor of Pharmacology, University of Liverpool

Professor Deenan Pillay Professor of Virology, UCL Pro-Vice-Provost International

Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FBPhS, FFPM (Hon) FMedSci David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Director of the Wolfson Centre for Personalised Medicine, Director of the Centre for Drug Safety Science

Professor Shirley Price MSc, PhD, FBTS, FRSB, ERT, FHEA ,FRSC, MBPharmacolSoc Emerita Professor of Toxicology, University of Surrey Visiting Profesor of Toxicology, University of Hertfordshire

Observers

Professor Stuart Ralston MB ChB MD FRCP FMedSci FRSE FFPM (Hon) Professor of Rheumatology, University of Edinburgh, Western General Hospital, Edinburgh

Department of Health & Social Care

Public Health England

NHS England & NHS Improvement

National Institute for Health and Care Excellence (NICE)

COVID-19 Vaccines Safety Surveillance Methodologies Expert Working Group

Remit

Pre-deployment phase

  • To landscape the different healthcare datasets that are currently available in the UK to capture near real-time information on COVID-19 vaccine exposure and study endpoints relevant to vaccine safety and potential for disease enhancement (and effectiveness). This should take into account a range of potential scenarios for vaccine deployment (i.e. the point of administration and any prioritised/targeted immunisation), and should advise on the need for further data capture and linkage.
  • To advise on the most suitable study endpoints and design(s) to monitor COVID-19 vaccine safety, and potential for disease enhancement (and effectiveness).
  • To support engagement with UK institutions who may be planning/in a position to conduct COVID-19 vaccine safety studies. This is to encourage and facilitate studies that are complementary in terms of objective and design, to avoid duplication and to accommodate a suitable range of study endpoints and scenarios for vaccine deployment.
  • To advise on proposals for enhanced passive surveillance.
  • To advise on communications in support of the pharmacovigilance strategy.

Post-deployment phase

  • To advise on the emerging evidence from all data sources on the risks and benefits of vaccine(s) during the course of any COVID-19 immunisation campaign in the UK. This includes measures to minimise risks, and optimise the benefit-risk balance for individual vaccines, such as any new precautions or restrictions on use.
  • To advise on any communications to health professionals and the public.
  • To advise on measures to monitor impact/effectiveness of any additional risk minimisation.

Chair

Dr Siraj Misbah MBBS (Hons) MSc FRCP FRCPath Consultant Clinical Immunologist, Lead for Clinical Immunology, Oxford University Hospitals & Chair of the Clinical Trials, Biologicals & Vaccines Expert Advisory Group (CTBVEAG) & Member of the Commission on Human Medicines (CHM)

Members

Professor Ian J Douglas BSc MSc PhD Senior Lecturer in Pharmacoepidemiology, London School of Hygiene & Tropical Medicine & Member of the Pharmacovigilance Expert Advisory Group (PEAG)

Professor Jonathan S Friedland MA PhD FRCP FRCPE FRCPI FESCMID FMedSci Deputy Principal, St. George’s, University of London & Chair of the Infections Expert Advisory Group (IEAG) & Member of the Commission on Human Medicines (CHM)

Sir Michael Jacobs MA PhD MB BS FRCP FRCP Edin DTM&H Clinical Director of Infection, Royal Free London NHS Foundation Trust & Hon. Senior Lecturer, Liverpool School of Tropical Medicine

Professor Simon De Lusignan Professor of Primary Care and Clinical Informatics, University of Oxford

Professor Rupert Payne MB ChB PhD MRCGP FRCPE FBPhS FHEA Professor of Primary Care & Clinical Pharmacology, University of Exeter. Member of the Pharmacovigilance Expert Advisory Group (PEAG)

Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FBPhS, FFPM (Hon) FMedSci David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Director of the Wolfson Centre for Personalised Medicine, Director of the Centre for Drug Safety Science

Professor Siobhan Quenby MBBS BSc MD FRCOG Professor of Obstetrics, Warwick University & Member of the Medicines for Women’s Health Expert Advisory Group (MWHEAG)

Professor Chris Robertson PhD MSc BSc Professor of Public Health Epidemiology, University of Strathclyde

Professor Calum Semple PhD FRCPCH FRCPE FHEA Professor of Outbreak Medicine University of Liverpool

Invited Experts

Professor Elizabeth Miller Department of Infectious Disease Epidemiology, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine

Professor Anthony Scott JCVI member, and Professor of vaccine epidemiology, Director HPRU in immunisation

Helen McDonald LSHTM Health Protection Research Unit

Jemma Walker LSHTM Health Protection Research Unit

Observers

Professor Liam Smeeth MBChB FRCGP FRCP MSc PhD FMedSci Professor of Clinical Epidemiology, London School of Hygiene & Tropical Medicine (LSHTM) & MHRA, Non-Executive Director (Board)

Visiting Experts

Professor Andrew Pollard FRCPCH PhD FMedSci Chief Investigator of the Oxford ChAD vaccine

Professor of Paediatric Infection and Immunity, Director of Graduate Studies, Department of Paediatrics, Vice Master, St Cross College, University of Oxford & Member of the Clinical Trials, Biologicals & Vaccines Expert Advisory Group (CTBVEAG)

Professor Robin Shattock Lead Scientist for the Imperial saRNA vaccine programme

Professor Sheena McCormack Clinical Project Lead at MRC CTU at UCL

COVID-19 Vaccines Benefit Risk Expert Working Group

Remit

  • To advise CHM on the quality, safety and efficacy of COVID-19 vaccines and on the balance of benefit and risks prior to authorisation.
  • To coordinate safety evaluation with the Clinical Trials, Biologicals and Vaccines Expert Advisory Group.
  • To report its conclusions and recommendations to the Commission on Human Medicines.
  • To advise on the emerging evidence from all data sources on the risks and benefits of vaccine(s) during the course of any COVID-19 immunisation campaign in the UK. This includes measures to minimise risks, and optimise the benefit-risk balance for individual vaccines, such as any new precautions or restrictions on use.
  • To advise on any communications to health professionals and the public.
  • To advise on measures to monitor impact/effectiveness of any additional risk minimisation.

Chair

Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FBPhS, FFPM (Hon) FMedSci, David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Director of the Wolfson Centre for Personalised Medicine, Director of the Centre for Drug Safety Science

Members

Professor Judith Breuer MD FRCPath FmedSci, Professor of Virology, University College London (UCL), Division of Infection and Immunity, London

Professor Gordon Dougan FRS, Department of Medicine, Cambridge Infectious Diseases, University of Cambridge

Mr V’Iain G Fenton-May BPharm MIPharm FRPharmS, Pharmaceutical Microbiologist

Professor Neil French MB ChB FRCP PhD, Head Department of Clinical Infection Microbiology and Immunology, Chair of Infectious Diseases & Global Health, Hon Consultant Infectious Diseases, Royal Liverpool & Broadgreen University Hospitals Trust

Professor David Goldblatt MB ChB FRCPCH FRCP PhD, Professor of Vaccinology and Immunology, Consultant in Paediatric Immunology, NIHR Senior Investigator, Great Ormond Street Hospital & University College London

Ms Susan Hunneyball BSc(Hons), Lay Member, Member of the Pharmacovigilance Expert Advisory Group (PEAG) and Advisory Board on the Registration of Homeopathic Products (ABRHP)

Professor Kimme Hyrich MD PhD FRCPC Professor of Epidemiology and Honorary, Consultant in Rheumatology, Centre for Musculoskeletal Research, Faculty of Biology Medicine and Health, University of Manchester and Kellgren Centre for Rheumatology, Manchester University NHS Foundation Trust

Sir Michael Jacobs MA PhD MB BS FRCP FRCP Edin DTM&H, Consultant in Infectious Diseases, Royal Free London NHS Foundation Trust; Hon. Senior Lecturer, University College London and Liverpool School of Tropical Medicine

Professor Helen J Lachmann MA MB BChir MD FRCP FRCPath, Professor of Medicine & Honorary Consultant Nephrologist, Clinical Director UCL Division of Medicine & Clinical Lead for National Amyloidosis Centre, University College London & Royal Free Hospital London NHS Foundation Trust & Vice-chair of the Clinical Trials, Biologicals & Vaccines Expert Advisory Group (CTBVEAG)

Professor Paul J Lehner PhD FRCP FMedSci FRS
Professor of Immunology and Medicine, Wellcome Trust Principal Research Fellow Honorary Consultant Infectious Diseases, Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre Cambridge Biomedical Campus

Mr Robert Lowe BPharm FRPharmS, Practising Hospital Pharmacist, Specialist Pharmacy Services - East of England

Dr Siraj Misbah MBBS (Hons) MSc FRCP FRCPath, Consultant Clinical Immunologist, Lead for Clinical Immunology, Oxford University Hospitals & Member of the Commission on Human Medicines (CHM) & Chair of the Clinical Trials, Biologicals & Vaccines Expert Advisory Group (CTBVEAG)

Professor Yvonne Perrie BSc Hons MRPharmS FAPS FSB PhD, Chair in Drug Delivery, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow. Scotland

Professor Shirley Price MSc, PhD, FBTS, FRSB, ERT, FHEA, FRSC, MBPharmacolSoc, Emerita Professor of Toxicology, University of Surrey, Visiting Professor of Toxicology, University of Hertfordshire and Member of the Commission on Human Medicines (CHM)

Dr Andrew Riordan MD FRCPCH DTM&H, Consultant in Paediatric Infectious Diseases and Immunology, Honorary Clinical Lecturer, University of Liverpool, Alder Hey Children’s NHS Foundation Trust, Liverpool

Professor Chris Robertson PhD MSc BSc, Professor of Public Health Epidemiology, University of Strathclyde

Professor Kevin M G Taylor BPharm PhD FRPharmS, Chair of the British Pharmacopoeia Commission and Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London

Dr Robin Thorpe BSc PhD FRCPath, Retired, Head, Division of Biotherapeutics, National Institute for Biological Standards and Control (NIBSC) & Member of the Clinical Trials, Biologicals & Vaccines Expert Advisory Group (CTBVEAG)

Professor Marc Turner MBBS PhD MBA FRCP FRCPath FHEA, Professor of Cellular Therapy; Medical Director Scottish National Blood Transfusion Service (SNBTS)

Professor Susannah Walsh BSc PhD MBA, Head of School, Professor of Pharmaceutical Microbiology, Pharmacy and Life Sciences, Robert Gordon University

Mrs Madeleine Wang BA (Hons), Lay Member & Member of the Clinical Trials, Biologicals & Vaccines Expert Advisory Group (CTBVEAG)

Professor Christopher Weir BSc MSc PhD FRSS, Cstat Professor of Medical Statistics & Clinical Trials, Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh & Member of Commission on Human Medicines (CHM)

Highly Personalised Medicines Expert Working Group (HPMEWG)

Remit

  • To advise CHM on the quality, safety and efficacy of candidate highly personalised medicines.
  • To advise CHM on the quality, non-clinical and clinical development of highly personalised medicines.
  • To advise on the measures to characterise the clinical effectiveness of highly personalised medicines group in the clinical use setting.
  • To advise on the measures to monitor short-term & long-term safety and minimise the risks of highly personalised medicines.
  • To advise on healthcare practitioner and patient communications related to highly personalised medicines and regulatory nomenclature of cancer vaccines and immunotherapy.

Chair

Professor Sir Munir Pirmohamed MB ChB (Hons) PhD FRCP FRCP (Edin) FBPhS, FFPM (Hon) FMedSci, David Weatherall Chair of Medicine, University of Liverpool, NHS Chair of Pharmacogenetics, Director of the Wolfson Centre for Personalised Medicine, Director of the Centre for Drug Safety Science

Members

Professor Cameron Alexander CChem, FRSC, FHEA Professor of Polymer Therapeutics, Division of Molecular Therapeutics and Formulation, School of Pharmacy, University of Nottingham

Dr Robert Andrews Senior Lecturer FHEA, Cardiff University, Board Member of ELIXIR-UK

Dr Colin Brown PhD FRCPath Consultant Clinical Scientist -Head of H&I Laboratory Colindale, NHS Blood and Transplant

Professor Robert Brown BSc PhD Professor of Translational Oncology, Department of Surgery & Cancer, Imperial College London

Dr Peter Buckle FRSPH, FIEHF, FIEA, C.ErgHF Principal Research Fellow, NIHR London In Vitro Diagnostics Co-operative Department of Surgery and Cancer, Faculty of Medicine, Imperial College London

Professor Tom Clutton-Brock MBE MB ChB FRCP FRCA FFICM Director, Medical Devices Testing and Evaluation Centre, Clinical Director, NIHR HealthTech Research Centre in Devices, digital and robotics (HRC-DDR), Chair, NICE Interventional Procedures Advisory Committee, Chair, MHRA Interim Devices Working Group, Associate Medical Director, University Hospitals Birmingham NHS Foundation Trust, Professor of Anaesthesia & Intensive Care Medicine, University of Birmingham

Professor Jamie Coleman MD MA (Med Ed) FRCP FBPhS Professor in Medical Education/Consultant Clinical Pharmacologist, University of Birmingham

Mrs Julia Cons Lay Representative

Professor Ann Daly BA PhD FBPhS Professor of Pharmacogenetics, Faculty of Medical Sciences, Newcastle University

Professor Jon Deeks PhD CStat Professor of Biostatistics Public Health, Epidemiology and Biostatistics, Institute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham

Dr Brendan Fish BSc PhD Director of Biologics & RNA Centre of Excellence, County Durham

Dr Vasantha Gowda MBBS FRCPCH MSc Paediatric Neurology Consultant & Paediatric Neuromuscular Service lead, Evelina London Children’s Hospital & Honorary Senior Lecturer, King’s College Hospital

Dr Alan Hodgkinson BSc (Hons), DPhil. Senior Lecturer, King’s College London

Dr Larissa Kerecuk FRCPCH Consultant Paediatric Nephrologist, Birmingham Women’s and Children’s NHS Foundation Trust

Professor Eric Lim MB ChB MD MSc FRCS(C-Th) Consultant Thoracic Surgeon, Royal Brompton Hospital, Professor of Thoracic Surgery, Imperial College London

Mr Robert Lowe BPharm FRPharmS Practising Hospital Pharmacist, Specialist Pharmacy Services - East of England

Professor Alan McIntyre PhD Director, Centre for Cancer Science, Biodiscovery Institute, School of Medicine, University of Nottingham

Dr Alisdair McNeill PhD FRCP (Edin) DCH FHEA
Senior Clinical Lecturer in Neurogenetics & Hon Consultant Clinical Geneticist and Associate Director of Student Affairs (Intercalation) & Editor-in-Chief European Journal of Human Genetics

Dr David Millrine PhD Translational Immunology Team lead, CRUK Cancer Biomarker Centre, University of Manchester

Professor Serena Nik-Zainal MA MBBChir MRCP PhD FMedSci NIHR Research Professor, Professor of Genomic Medicine & Bioinformatics, Early Cancer Institute, University of Cambridge, Department of Medical Genetics, Honorary Consultant in Clinical Genetics, Cambridge University Hospitals NHS Trust

Professor Christian Ottensmeier MD, PhD, FRCP. Professor of Molecular and Clinical Cancer Medicine, University of Liverpool

Professor Poulam Patel PhD, MBBS, FRCP Professor of Clinical Oncology, University of Nottingham

Professor Yvonne Perrie BSc PhD Chair in Drug Delivery, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow. Scotland

Professor Shirley Price MSc, PhD, FBTS, FRSB, ERT, FHEA, FRSC, MBPharmacolSoc Emerita Professor of Toxicology, University of Surrey, Visiting Professor of Toxicology, University of Hertfordshire

Professor Carlo Rinaldi MA MD PhD MSc Associate Professor in Neuroscience, University of Oxford

Professor Jacqui Shaw BSc PhD Group Leader and Professor of Translational Cancer Genetics, Leicester University

Professor James Spicer FRCP, PhD Professor of Experimental Cancer Medicine, King’s College London; Consultant in Medical Oncology, Guy’s & St Thomas’ NHS Foundation trust

Professor Nigel Stallard Professor of Medical Statistics, Deputy Director Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry

Professor Kevin M G Taylor BPharm PhD FRPharmS Emeritus Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London

Professor Robert W. Taylor PhD DSc FRCPath Professor of Mitochondrial Pathology, Mitochondrial Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University Head, Highly Specialised Mitochondrial Laboratory, Newcastle upon Tyne Hospitals NHS Foundation Trust, Scientific Director, North East and Yorkshire Genomic Laboratory Hub Chair, Association for Clinical Genomic Science

Dr Robin Thorpe BSc PhD FRCPath Retired, Head, Division of Biotherapeutics, National Institute for Biological Standards and Control (NIBSC)

Dr David Turner PhD FRCPath H&I Laboratory, Scottish National Blood Transfusion Service, Royal Infirmary of Edinburgh

Professor Marc Turner MBBS PhD MBA FRCP FRCPath FHEA Professor of Cellular Therapy; Medical Director Scottish National Blood Transfusion Service

Professor Christopher Weir BSc MSc PhD FRSS Cstat Professor of Medical Statistics & Clinical Trials, Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh

Professor Anthony Williams BSc MSc MRCP, FRCPath, PhD Professor of Translational Medicine and Honorary Consultant in Clinical Immunology and Allergy, University of Southampton and University Hospital Southampton NHS Trust

Professor Christopher Yau MA MEng DPhil Professor of Artificial Intelligence, Nuffield Department of Women’s & Reproductive Health, University of Oxford and Health Data Research UK

Professor Ly-Mee Yu BSc MSc DPhil Professor of Clinical Trials and Biostatistics, Deputy Director Academic of Primary Care Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford

Observers

Professor Peter Johnson National Clinical Director for Cancer, England

Dr Jayne Spink Prostate Cancer Research

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