Intrarectal quinine for treating Plasmodium falciparum malaria.

From:
Department for International Development
Published
1 January 2005
Document Type:
Literature Review
Theme:
Health
Authors:
Eisenhut, M., Omari, A.A.A.

Abstract

In children, quinine given through the rectum may be as effective as intravenous and intramuscular quinine for treating uncomplicated Plasmodium falciparum malaria. The data reviewed also lead to the conclusion that a diluted quinine solution given intrarectally using a syringe for two to three days has less harmful effects compared with intramuscular quinine given for the same time period. Administration of intrarectal quinine is significantly less painful than intramuscular injection of quinine. More trials are needed for patients with severe malaria and in adults.

Citation

The Cochrane Database of Systematic Reviews 2005, Issue 1. Art. No.: CD004009. DOI: 10.1002/14651858.CD004009.pub2.

Intrarectal quinine for treating Plasmodium falciparum malaria.

Published 1 January 2005
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