Letters and medicine recalls sent to healthcare professionals in April 2021

A summary of letters and recent medicine recalls and notifications sent to healthcare professionals.

• From: Medicines and Healthcare products Regulatory Agency
• Published: 19 May 2021

• Therapeutic area: Endocrinology, diabetology and metabolism, Infectious disease, Nutrition and dietetics and Ophthalmology

Letters

In April 2021, the following letters were sent or provided to relevant healthcare professionals:

• EYLEA 40 mg/mL (aflibercept solution for intravitreal injection): Higher risk of intraocular pressure increase with the pre-filled syringe
• Colomycin (Colistimethate Sodium), 1 million IU, Powder for solution for injection, infusion or inhalation: replacement with Spanish Colomycin 1 million IU vials over-labelled with the UK label during supply shortage

Medicine Recalls and Notifications

Class 2 Medicines Recall: Ennogen Pharma Limited, Trimethoprim 200mg Tablets (PL 40147/0083), EL (21)A/10. A batch of Trimethoprim 200mg tablets is being recalled following complaints of a foreign tablet present in sealed containers. Following investigation, the foreign tablet was confirmed as Ennogen’s 100mg Trimethoprim tablet. Stop supplying the batch immediately, quarantine all remaining stock and return to supplier.

Medical Device Safety Information

Recent MHRA Device Safety Information pages have been published on:

• Dexcom G6 Sensor: untested barrier methods to reduce skin reactions
• Total parenteral (TPN) and enteral nutrition bags manufactured by Diffuplast: Sterilisation issue

For all of the latest safety notices from the MHRA on drugs and medical devices, see Alerts and recalls for drugs and medical devices.

Article citation: Drug Safety Update volume 14, issue 10: May 2021: 3.

Published 19 May 2021