Drug Safety Update

Topiramate is now contraindicated in pregnancy and in women of childbearing potential unless the conditions of a Pregnancy Prevention Programme are fulfilled.…

• Therapeutic area: Neurology and 2 others
• Published: 20 June 2024

We have initiated a new safety review into topiramate as a result of an observational study reporting an increased risk of neurodevelopmental disabilities in children whose mothers took topiramate during pregnancy.…

• Therapeutic area: Neurology and 2 others
• Published: 21 July 2022

A review of the risks of major congenital malformations and of adverse neurodevelopmental outcomes for antiepileptic drugs by the Commission on Human Medicines has confirmed that lamotrigine (Lamictal) and levetiracetam (Kep…

• Therapeutic area: Neurology and 1 others
• Published: 7 January 2021