Guidance
References
Updated 19 March 2025
- Liu FH, Z-D, Zhao X-M, Zhao W-N, Feng Z-X, Yurko, A, Alwasel S, Boekhout T, Bensch K, Hui F-L, Bai F-Y, Wang Q-M. ‘Phylogenomic analysis of the Candida auris-Candida haemuli clade and related taxa in the Metschnikowiaceae, and proposal of 13 new genera, 55 new combinations and 9 new species’ Persoonia - Molecular Phylogeny and Evolution of Fungi 2024: volume 52, pages 22 to 43
- Jones CR, Neill C, Borman AM, Budd EL, Cummins M, Fry C and others. ‘The laboratory investigation, management, and infection prevention and control of Candida auris: a narrative review to inform the 2024 national guidance update in England’ Journal of Medical Microbiology 2024: volume 73, issue 5
- Satoh K, Makimura K, Hasumi Y, Nishiyama Y, Uchida K, Yamaguchi H. ‘Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital’ Microbiology and Immunology 2009: volume 53, issue 1, pages 41 to 44
- Fisher MC, Denning DW. ‘The WHO fungal priority pathogens list as a game-changer’ Nature Reviews Microbiology 2023: volume 21, issue 4, pages 211 to 212
- Dang T, Bassett J, Souri A, Nutt A, Honza H, Retana D and others. ‘Transmission of pan-resistant and echinocandin-resistant Candida auris between healthcare facilities during the COVID-19 pandemic’ American Journal of Infection Control 2022: volume 50, 7 supplement, S2 to S3
- Biswal M, Rudramurthy SM, Jain N, Shamanth AS, Sharma D, Jain K and others. ‘Controlling a possible outbreak of Candida auris infection: lessons learnt from multiple interventions’ Journal of Hospital Infections 2017: volume 97, issue 4, pages 363 to 370
- Sansom SE, Gussin GM, Schoeny M, Singh RD, Adil H, Bell P and others. ‘Rapid environmental contamination With Candida auris and multidrug-resistant bacterial pathogens near colonized patients’ Clinical Infectious Diseases 2024: volume 78, issue 5, pages 1,276 to 1,284
- Bergeron G, Bloch D, Murray K, Kratz M, Parton H, Ackelsberg J and others. ‘Candida auris colonization after discharge to a community setting: New York City 2017 to 2019’ Open Forum Infectious Diseases 2021: volume 8, issue 1, page ofaa620
- Rossow J, Ostrowsky B, Adams E, Greenko J, McDonald R, Vallabhaneni S and others. ‘Factors associated with Candida auris colonization and transmission in skilled nursing facilities with ventilator units, New York 2016 to 2018’ Clinical Infectious Diseases 2021: 72, issue 11, pages e753 to e60
- Hu S, Zhu F, Jiang W, Wang Y, Quan Y, Zhang G and others. ‘Retrospective analysis of the clinical characteristics of Candida auris infection worldwide from 2009 to 2020’ Frontiers in Microbiology 2021: volume 12, page 658,329
- Alvarez-Moreno CA, Morales-López S, Rodriguez GJ, Rodriguez JY, Robert E, Picot C and others. ‘The mortality attributable to Candidemia in C. auris Is higher than that in other candida species: myth or reality?’ Journal of Fungi (Basel) 2023: volume 9, issue 4
- Forgács L, Borman AM, Prépost E, Tóth Z, Kardos G, Kovács R and others. ‘Comparison of in vivo pathogenicity of 4 Candida auris clades in a neutropenic bloodstream infection murine model’ Emerging Microbes and Infections 2020: volume 9, issue 1, pages 1,160 to 1,169
- Borman AM, Johnson EM. ‘Candida auris in the UK: Introduction, dissemination and control’ PLoS Pathogens 2020: volume 16, issue 7, article e1008563
- Eyre DW, Sheppard AE, Madder H, Moir I, Moroney R, Quan TP and others. ‘A Candida auris outbreak and its control in an intensive care setting’ New England Journal of Medicine 2018: volume 379, issue 14, pages 1,322 to 1,331
- Schelenz S, Hagen F, Rhodes JL, Abdolrasouli A, Chowdhary A, Hall A and others. ‘First hospital outbreak of the globally emerging Candida auris in a European hospital’ Antimicrobial Resistance and Infection Control 2016: volume 5, issue 35
- Taori SK, Khonyongwa K, Hayden I, Athukorala GDA, Letters A, Fife A and others. ‘Candida auris outbreak: mortality, interventions and cost of sustaining control’ Journal of Infection 2019: volume 79, issue 6, pages 601 to 611
- Taori SK, Rhodes J, Khonyongwa K, Szendroi A, Smith M, Borman AM and others. ‘First experience of implementing Candida auris real-time PCR for surveillance in the UK: detection of multiple introductions with two international clades and improved patient outcomes’ Journal of Hosp Infections 2022: volume 127, pages 111 to 120
- Borman AM, Fraser M, Johnson EM. ‘CHROMagar™ Candida Plus: a novel chromogenic agar that permits the rapid identification of Candida auris’ Medical Mycology 2021: volume 59, issue 3, pages 253 to 258
- de Jong AW, Dieleman C, Carbia M, Mohd Tap R, Hagen F. ‘Performance of 2 novel chromogenic media for the identification of multidrug-resistant Candida auris compared with other commercially available formulations’ Journal of Clinical Microbiology 2021: volume 59, issue 4
- Abdolrasouli A, Fraser MA. ‘Candida auris identification and profiling by MALDI-ToF mass spectrometry’ Methods in Molecular Biology 2022: volume 2,517, pages 21 to 32
- Leach L, Zhu Y, Chaturvedi S. ‘Development and validation of a real-time PCR assay for rapid detection of Candida auris from surveillance samples’ Journal of Clinical Microbiology 2018: volume 56, issue 2
- Lyman M, Forsberg K, Sexton DJ, Chow NA, Lockhart SR, Jackson BR and others. ‘Worsening spread of Candida auris in the United States, 2019 to 2021’ Annals of Internal Medicie 2023: volume 176, issue 4, pages 489 to 495
- Jacobs SE, Jacobs JL, Dennis EK, Taimur S, Rana M, Patel D and others. ‘Candida auris pan-drug-resistant to 4 classes of antifungal agents’ Antimicrobial Agents and Chemotherapy 2022: volume 66,. issue 7, article e0005322
- Brooks RB, Walters M, Forsberg K, Vaeth E, Woodworth K, Vallabhaneni S. ‘Candida auris in a US patient with carbapenemase-producing organisms and recent hospitalization in Kenya’ Morbidity and Mortality Weekly Report 2019: volume 68, issue 30, pages 664 to 666
- Cornely OA, Bassetti M, Calandra T, Garbino J, Kullberg BJ, Lortholary O and others. ‘Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM’ Lancet Infectious Diseases (published online 13 February 2025 ahead of print) (accessed on 1 March 2025)
- Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L and others. ‘Clinical practice guideline for the management of candidiasis: 2016 update by the Infectious Diseases Society of America’ Clinical Infectious Diseases 2016: volume 62, issue 4, pages e1 to e50
- Lionakis MS, Chowdhary A. ‘Candida auris infections’ New England Journal of Medicine 2024: volume 391, issue 20, pages 1,924 to 1,935
- Simon SP, Li R, Silver M, Andrade J, Tharian B, Fu L and others. ‘Comparative outcomes of Candida auris bloodstream infections: a multicenter retrospective case-control study’ Clinical Infectious Diseases 2023: volume 76, issue 3, pages e1436 to e1443
- Wake RM, Allebone-Salt PE, John LLH, Caswall BA, Govender NP, Ben-Ami R and others. ‘Optimizing the treatment of invasive Candidiasis-A case for combination therapy’ Open Forum Infectious Diseases 2024: volume 11, issue 6, article ofae072
- Balla N, Kovacs F, Balazs B, Borman AM, Bozo A, Jakab A and others. ‘Synergistic interaction of caspofungin combined with posaconazole against FKS wild-type and mutant Candida auris planktonic cells and biofilms’ Antibiotics 2022: volume 11, issue 11 (no pagination)
- Fakhim H, Chowdhary A, Prakash A, Vaezi A, Dannaoui E, Meis JF and others. ‘In vitro interactions of echinocandins with triazoles against multidrug-resistant Candida auris’ Antimicrobial Agents and Chemotherapy 2017: volume 61, issue 11
- Jaggavarapu S, Burd EM, Weiss DS. ‘Micafungin and amphotericin B synergy against Candida auris’ The Lancet Microbe 2020: volume 1, issue 8, pages e314 to e315
- John LLH, Thomson DD, Bicanic T, Hoenigl M, Brown AJP, Harrison TS and others. ‘Heightened efficacy of Anidulafungin when used in combination with Manogepix or 5-Flucytosine against Candida auris in vitro’ Antimicrobial Agents and Chemotherapy 2023: artcle e0164522
- Lepak AJ, Zhao M, Berkow EL, Lockhart SR, Andes DR. ‘Pharmacodynamic optimization for treatment of invasive Candida auris infection’ Antimicrobial Agents and Chemotherapy 2017: volume 61, issue 8
- O’Brien B, Liang J, Chaturvedi S, Jacobs JL, Chaturvedi V. ‘Pan-resistant Candida auris: New York subcluster susceptible to antifungal combinations’ Lancet Microbe 2020: volume 1, issue 5, pages e193 to e194
- Felton T, Troke PF, Hope WW. ‘Tissue penetration of antifungal agents’ Clinical Microbiology Reviews 2014: volume 27, issue 1, pages 68 to 88
- Ham YY, Lewis JS, Thompson GR. ‘Rezafungin: A novel antifungal for the treatment of invasive candidiasis’ Future Microbiology 2021: volume 16, issue 1, pages 27 to 36
- Pfaller MA, Huband MD, Rhomberg PR, Bien PA, Castanheira M. ‘Activities of Manogepix and comparators against 1,435 recent fungal isolates collected during an international surveillance program (2020)’ Antimicrobial Agents and Chemotherapy 2022: volume 66, issue 11, article e0102822
- Vazquez JA, Pappas PG, Boffard K, Paruk F, Bien PA, Tawadrous M and others. ‘Clinical efficacy and safety of a novel antifungal, Fosmanogepix, in patients with candidemia caused by Candida auris: results from a phase 2 trial’ Antimicrobial Agents and Chemotherapy 2023: article e0141922
- Leroux S, Jacqz-Aigrain E, Elie V, Legrand F, Barin-Le Guellec C, Aurich B and others. ‘Pharmacokinetics and safety of fluconazole and micafungin in neonates with systemic candidiasis: a randomized, open-label clinical trial’ British Journal of Clinical Pharmacology 2018: volume 84, issue 9, pages 1,989 to 1,999
- Hope WW, Mickiene D, Petraitis V, Petraitiene R, Kelaher AM, Hughes JE and others. ‘The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates’ Journal of Infectious Diseases 2008: volume 197, issue 1, pages 163 to 171
- Kenters N, Kiernan M, Chowdhary A, Denning DW, Pemán J, Saris K and others. ‘Control of Candida auris in healthcare institutions: outcome of an International Society for Antimicrobial Chemotherapy expert meeting’ International Journal of Antimicrobial Agents 2019: volume 54, issue 4, pages 400 to 406
- Abdolrasouli A, Armstrong-James D, Ryan L, Schelenz S. ‘In vitro efficacy of disinfectants utilised for skin decolonisation and environmental decontamination during a hospital outbreak with Candida auris’ Mycoses 2017: volume 60, issue 11, pages 758 to 763
- Moore G, Schelenz S, Borman AM, Johnson EM, Brown CS. ‘Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris’ Journal of Hospital Infection 2017: volume 97, issue 4, pages 371 to 375
- Sherry L, Ramage G, Kean R, Borman A, Johnson EM, Richardson MD and others. ‘Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris’ Emerging Infectious Diseases 2017: volume 23, issue 2, pages 328 to 331
- Omardien S, Teska P. ‘Skin and hard surface disinfection against Candida auris: what we know today’ Frontiers in Medicine 2024: volume 11, page 1,312,929
- Ghannoum M, Herrada J, McCormick TS, Long L. ‘A novel transdermal application for clearing skin colonization by Candida auris’ Antimicrobial Agents and Chemotherapy 2021: volume 65, issue 5, pages e02303 to e02320
- Wei L, Li Y, Li X, Bian L, Wen Z, Li M. ‘Chlorhexidine-impregnated dressing for the prophylaxis of central venous catheter-related complications: a systematic review and meta-analysis’ BMC Infectious Diseases 2019: volume 19, issue 1, page 429
- Garcia-Bustos V, Salavert M, Ruiz-Gaitán AC, Cabañero-Navalon MD, Sigona-Giangreco IA, Pemán J. ‘A clinical predictive model of candidaemia by Candida auris in previously colonized critically ill patients’ Clinical Microbiology and Infection 2020: volume 26, issue 11, pages 1,507 to 1,513
- Shastri PS, Shankarnarayan SA, Oberoi J, Rudramurthy SM, Wattal C, Chakrabarti A. ‘Candida auris candidaemia in an intensive care unit: prospective observational study to evaluate epidemiology, risk factors, and outcome’ Journal of Critical Care 2020: volume 57, pages 42 to 48
- Johnson MD, Lewis RE, Dodds Ashley ES, Ostrosky-Zeichner L, Zaoutis T, Thompson GR and others. ‘Core recommendations for antifungal stewardship: a statement of the Mycoses Study Group Education and Research Consortium’ Journal of Infectious Diseases 2020: volume 222, suplement 3, pages S175 to s98
- Whitney L, Al-Ghusein H, Glass S, Koh M, Klammer M, Ball J and others. ‘Effectiveness of an antifungal stewardship programme at a London teaching hospital 2010 to 2016’ Journal of Antimicrobial Chemotherapy 2019: volume 74, issue 1, pages 234 to 241
- Micallef C, Ashiru-Oredope D, Hansraj S, Denning DW, Agrawal SG, Manuel RJ and others. ‘An investigation of antifungal stewardship programmes in England’ Journal of Medical Microbiology 2017: volume 66, issue 11, pages 1,581 to 1,589
- Hart E, Nguyen M, Allen M, Clark CM, Jacobs DM. ‘A systematic review of the impact of antifungal stewardship interventions in the United States’ Annals of Clinical Microbiology and Antimicrobials 2019: volume 18, issue 1, page 24
- Caceres DH, Forsberg K, Welsh RM, Sexton DJ, Lockhart SR, Jackson BR and others. ‘Candida auris: a review of recommendations for detection and control in healthcare settings’ Journal of Fungi 2019: volume 5, issue 4
- Ahmad S, Alfouzan W. ‘Candida auris: epidemiology, diagnosis, pathogenesis, antifungal susceptibility, and infection control measures to combat the spread of infections in healthcare facilities’ Microorganisms 2021: volume 9, issue 4
- Chakrabarti A, Sood P. On the emergence, spread and resistance of Candida auris: host, pathogen and environmental tipping points’ Journal of Medical Microbiology 2021: volume 70, issue 3
- Yadav A, Singh A, Wang Y, Haren MHV, Singh A, de Groot T and others. ‘Colonisation and transmission dynamics of Candida auris among chronic respiratory diseases patients hospitalised in a chest hospital, Delhi, India: a comparative analysis of whole genome sequencing and microsatellite typing’ Journal of Fungi 2021: volume 7, issue 2
- Welsh RM, Bentz ML, Shams A, Houston H, Lyons A, Rose LJ and others. ‘Survival, persistence, and isolation of the emerging multidrug-resistant pathogenic yeast Candida auris on a plastic health care surface’ Journal of Clinical Microbiology 2017: volume 55, issue 10, pages 2,996 to 3,005
- de Almeida JN, Jr., Francisco EC, Hagen F, Brandão IB, Pereira FM, Presta Dias PH and others, ‘Emergence of Candida auris in Brazil in a COVID-19 intensive care unit’ Journal of Fungi 2021: volume 7, issue 3
- Decker BK, Clancy CJ. ‘Lanyards as source of a Candida auris outbreak: as you investigate the environment, do not overlook hand hygiene’ Critical Care Medicine 2021: pages 714 to 716
- Nobrega de Almeida J, Jr., Brandão IB, Francisco EC, de Almeida SLR, de Oliveira Dias P, Pereira FM and others. ‘Axillary digital thermometers uplifted a multidrug-susceptible Candida auris outbreak among COVID-19 patients in Brazil’ Mycoses 2021: volume 64, issue 9, pages 1,062 to 1,072
- Patterson CA, Patel A, Newsholme W, Tan M, Edgeworth JD, Wyncoll D and others. ‘Cloth lanyards as a source of intermittent transmission of Candida auris on an ICU’ Critical Care Medicine 2021: pages 697 to 701
- CDC. ‘Infection control guidance: Candida auris 2024’ (cited 11 August 2024)
- Weber DJ, Rutala WA, Sickbert-Bennett E. ‘Emerging infectious diseases, focus on infection prevention, environmental survival and germicide susceptibility: SARS-CoV-2, Mpox, and Candida auris’ American Journal of Infection Control 2023: volume 51, issue 11s, pages a22 to a34