Clostridioides difficile infection: guidance on management and treatment
Options, agents, recommendations and algorithms for the treatment of Clostridioides difficile (C. difficile) infection.
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The antimicrobial treatment recommendations in the existing Public Health England (PHE) Clostridioides difficile: guidance on management and treatment (2013) have been superseded by the National Institute for Health and Care Excellence (NICE) guideline on Clostridioides difficile infection (CDI).
A full update to the current PHE CDI guidelines is planned for later this year. Please continue to refer to the current PHE guidance for:
- management of life-threatening disease
- guidance on diagnosis
- guidance on infection control
Updates to this page
Published 1 June 2013Last updated 23 July 2021 + show all updates
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Added link to new NICE guidelines.
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Replaced name 'Clostridium difficile' with 'Clostridioides difficile' to reflect changes in microbial taxonomy.
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First published.