Guidance

List of most commonly encountered drugs currently controlled under the misuse of drugs legislation

Updated 8 August 2022

The following is a list of the most commonly encountered drugs currently controlled under the misuse of drugs legislation showing their respective classifications under both the Misuse of Drugs Act 1971 (MDA) and the Misuse of Drugs Regulations 2001 (MDR).

Although it is extensive, the list is not exhaustive and, in the event of a substance not being listed below, reference should also be made to the published Act and Regulations at legislation.gov.uk, specifically Parts I, II, III and IV of Schedule 2 to the Misuse of Drugs Act 1971 and in Schedules 1 to 5 to the Misuse of Drugs Regulations 2001.

Please note that on opening the content of any item of legislation that has outstanding changes and effects waiting to be applied to it, the outstanding effects are listed at the top of the provision.

This list is not exhaustive. All salts (e.g. calcium, HCl, sodium and sulphate), stereoisomers, esters, ethers, preparations and products are also controlled where stated in the legislation.

Drug Class Schedule
MDA MDR
Acetorphine A 2
Acetyldihydrocodeine B[footnote 1] 2/5[footnote 2]
Adinazolam C 1
Alfentanil A 2
Allobarbital (allobarbitone) B 3
Allyl(α-methyl-3,4-methylenedioxyphenethyl)amine (MDAL) A 1
Allylprodine A 2
Alphacetylmethadol A 2
Alphameprodine A 2
Alphamethadol A 2
α-Methylfentanyl A 1
Alphaprodine A 2
Alphenal (5-Allyl-5-Phenylbarbituric acid) B 3
Alprazolam C 4 Pt1
Amineptine C 2
Aminorex C 4 Pt1
Amphetamine B[footnote 1] 2
Amobarbital (Amylobarbitone) B 3
Androst-4-ene-3,17-diol (4-Androstenediol) C 4 Pt2
Anhydroecgonine A 2
Anileridine A 2
Aprobarbital (Aprobarbitone) B 3
Atamestane C 4 Pt2
Barbital (Barbitone) B 3
Barbituric acid, (any 5,5-disubstituted) B 3
Benzethidine A 2
Benzoylecgonine A 2
Benzphetamine C 3
Benzyl(α-Methyl-3,4-methylenedioxyphenethyl)amine A 1
Benzylmorphine (3-Benzylmorphine) A 2
Betacetylmethadol A 2
Betameprodine A 2
Betamethadol A 2
β-Methoxy-3,4-methylenedioxyphenethylamine A 1
Betaprodine A 2
Bezitramide A 2
Bolandiol C 4 Pt2
Bolasterone C 4 Pt2
Bolazine C 4 Pt2
Boldenone C 4 Pt2
Boldione C 4 Pt2
Bolenol C 4 Pt2
Bolmantalate C 4 Pt2
Bromazepam C 4 Pt1
Bromazolam C 1
Bromophenethylamine A 1
Brotizolam C 4 Pt1
Bufotenine (5-Methoxydimethyltryptamine) A 1
Buprenorphine C 3
Butabarbital (Secbutobarbital) B 3
Butalbital B 3
Butallylonal B 3
Butethal (Butobarbital/Butobarbitone) B 3
Calusterone C 4 Pt2
Camazepam C 4 Pt1
Cannabinol B 1
Cannabinol derivatives (except dronabinol or its stereoisomers) B 1
Cannabis B 1[footnote 11]
cannabis resin B 1
cannabis oil B 1
“Sativex” B 4 Pt1[footnote 10]
Carfentanyl (Carfentanil) A 2
Cathine ((+)-norpseudoephedrine) C 3
Cathinone C 1
Cathinone derivatives B 1
CBPMs B 2
Chlordiazepoxide C 4 Pt1
Chloromethamphetamine B 1
Chloroamphetamine A 1
Chlorphentermine C 3
Chlorophenethylamine A 1
Chorionic gonadotrophin (HCG) C 4 Pt2
Clenbuterol C 4 Pt2
Clobazam C 4 Pt1
Clonazepam C 4 Pt1
Clonazolam C 1
Clonitazene A 2
Clorazepic acid (Clorazepate) C 4 Pt1
Clostebol C 4 Pt2
Clotiazepam C 4 Pt1
Cloxazolam C 4 Pt1
Coca leaf A 1
Cocaethylene (ethylbenzoylecgonine) A 2
Cocaine A 2
Codeine B[footnote 1] 2/5[footnote 2]
Cyclobarbital (Cyclobarbitone) B 3
Cyclopentobarbital (Cyclopentobarbitone) B 3
Cyclopropylmethyl(α-Methyl-3,4-methylenedioxyphenethyl)amine A 1
Danazol C 4 Pt2
Delorazepam C 4 Pt1
Deschloroetizolam C 1
Desomorphine A 2
Desoxymethyltestosterone C 4 Pt2
Desoxypipradrol (2-Diphenylmethyl-piperidine, 2-DPMP) B 1
Dextromoramide A 2
Dextropropoxyphene C 2/5[footnote 3]
Diamorphine (Diacetylmorphine) A 2
Diampromide A 2
Diazepam C 4 Pt1
Diclazepam C 1
Diethylpropion C 3
Diethylthiambutene A 2
Difenoxin A 2/5[footnote 4]
Dihydrocodeine B[footnote 1] 2/5[footnote 2]
Dimethyl(α-methyl-3,4-methylenedioxyphenethyl)amine A 1
α,α-Dimethyl-3,4-methylenedioxyphenethylamine A 1
α,α-Dimethyl-3,4-methylenedioxyphenethyl(methyl)amine A 1
Dihydrocodeinone-O-carboxymethyloxime A 2
Dihydroetorphine A 2
Dihydromorphine A 2
Dimenoxadole A 2
Dimepheptanol A 2
Dimethylthiambutene A 2
Dioxaphetyl butyrate A 2
Diphenoxylate A 2/5[footnote 5]
Diphenylprolinol (Diphenyl-2-pyrrolidinyl-methanol, D2PM) B 1
Dipipanone A 2
Dronabinol B 2
Drotebanol (3,4-Dimethoxy-17-methylmorphinan- 6, 14-diol) A 2
Drostanolone C 4 Pt2
Ecgonine and any derivative of ecgognine which is convertible to ecgonine or cocaine A 2
Enestebol C 4 Pt2
Epidyolex B 5
Epitiostanol C 4 Pt2
Estazolam C 4 Pt1
Ethchlorvynol C 3
Ethinamate C 3
Ethyl loflazepate C 4 Pt1
Ethylmethylthiambutene A 2
Ethylmorphine (3-Ethylmorphine) B[footnote 1] 2[footnote 2]
Ethylnaphthidate B 1
Ethyloestrenol C 4 Pt2
Ethylphenidate B 1
Eticyclidine A 1
Etizolam C 1
Etonitazene A 2
Etorphine A 2
Etoxeridine A 2
Etryptamine A 1
Fencamfamin C 4 Pt1
Fenethylline C 2
Fenproporex C 4 Pt1
Fentanyl A 2
Flualprazolam C 1
Flubromazepam C 1
Flubromazolam C 1
Fludiazepam C 4 Pt1
Flunitrazepam C 3
Flunitrazolam C 1
Fluorophenethylamine A 1
Fluoxymesterone C 4 Pt2
Flurazepam C 4 Pt1
Fonazepam C 1
Formebolone C 4 Pt2
Fungus (of any kind) which contains psilocin or an ester of psilocin A 1
Furazabol C 4Pt2
Furethidine A 2
Gabapentin (1-(aminomethyl) cyclohexaneacetic acid) C 3
Gamma-butyrolactone (GBL) (for human ingestion) B n/a[footnote 9]
Gamma-hydroxybutyrate (GHB - 4-Hydroxy-n-butyric acid) B 2
Gestrinone C 4 Pt2
Glutethimide B 2
Halazepam C 4 Pt1
Haloxazolam C 4 Pt1
Heptobarbital (Heptobarbitone) B 3
Hexethal B 3
Homoveratrylamine (3,4-Dimethoxyphenethylamine) A 1
Hydroxybenzoylecgonine A 2
Hydroxycocaine A 2
Hydrocodone (dihydrocodeinone) A 2
Hydromorphinol (14-Hydroxydihydromorphine) A 2
Hydromorphone A 2
Hydroxypethidine A 2
Isomethadone A 2
Isopropylphenidate B 1
Ketamine B 2
Ketazolam C 4 Pt1
Ketobemidone A 2
Khat C 1
Lefetamine B 2
Levomethorphan A 2
Levomoramide A 2
Levophenacylmorphan A 2
Levorphanol/Dextrorphan A 2
Lisdexamphetamine B 2
Lofentanil A 2
Loprazolam C 4 Pt1
Lorazepam C 4 Pt1
Lormetazepam C 4 Pt1
Lysergamide A 1
Lysergic acid diethylamide (LSD) A 1
Lysergic Acid N-(Methylopropyl) Amide A 1
Lysergide (& other N-alkyl derivatives of lysergamide) A 1
Mazindol C 3
Mebolazine C 4 Pt2
Meclonazepam C 1
Mecloqualone B 2
Medazepam C 4 Pt1
Mefenorex C 4 Pt1
Mephentermine C 3
Mepitiostane C 4 Pt2
Meprobamate C 3
Mesabolone C 4 Pt2
Mescaline A 1
Mesocarb C 4 Pt1
Mestanolone C 4 Pt2
Metazocine A 2
Mesterolone C 4 Pt2
Methadone A 2
Methadyl acetate A 2
Methylamphetamine A 2
Methylmorphenate B 1
Methylnaphthidate B 1
α-Methyl-3,4-methylenedioxyphenethyl(prop-2-ynyl)amine A 1
α-Methylphenethylhydroxylamine B 2
Methandienone C 4 Pt2
Methandriol C 4 Pt2
Methaqualone B 2
Methcathinone (Ephedrone) B 1
Methenolone C 4 Pt2
Methoxyphenethylamine A 1
Methyldesorphine A 2
Methyldihydromorphine (6-methyldihydromorphine) A 2
Methylecgonine A 2
Methylenedioxyamphetamine (MDA) A 1
Methylenedioxyethylamphetamine (MDEA) A 1
Methylenedioxypyrovalerone (MDPV) B 1
Methylphenidate B[footnote 1] 2
Methylphenobarbital (Methylphenobarbitone) B 3
Methyltestosterone C 4 Pt2
Methyprylone C 3
Metizolam C 1
Metopon A 2
Metribolone C 4 Pt2
Mibolerone C 4 Pt2
Midazolam C 3
Morpheridine A 2
Morphine A 2/5[footnote 6]
3-Monoacetylmorphine (3-MAM) A 2
6-Monoacetylmorphine (6-MAM) A 2
Morphine-3-B-D-Glucoride-N-Oxide A 2
Morphine-3-B-D-Glucuronide A 2
Morphine-6-B-D-glucuronide-N-oxide A 2
Morphine methobromide (& morphine N-oxide & other pentavalent nitrogen morphine derivatives) A 2
Myrophine A 2
N-Benzyl-ethylphenidate B 1
N-Benzylpethidine A 1
N-(4-sec-Butylthio-2,5-dimethoxyphenethyl)hydroxylamine A 1
N-(2,5-Dimethoxy-4-propylthiophenthyl)hydroxylamine A 1
N-(4-Ethylthio-2,5-dimethoxyphenethyl)hydroxylamine A 1
N,N-Diethyltryptamine (DET) A 1
N,N-Dimethyltryptamine (DMT) A 1
N-Ethylamphetamine C 4 Pt1
N-Ethyl-1(3-methoxyphenyl)cyclohexylamine (3-MeO-PCE) B 1
N-Hydroxy-tenamphetamine (MDOH) A 1
N-Methylhomoveratrylamine A 1
N-Methyl Lysergic Acid Diethylamide A 1
N-Methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) A 1
N-Methyl-N-(α-methyl-3,4-methylenedioxyphenethyl)hydroxylamine A 1
N-Methyltryptamine A 1
Nabilone B 2
Nandrolone C 4 Pt2
Napthylpyrovalerone (naphyrone) B 1
Nealbarbitone B 3
N-ethyl-nor-ketamine B 1
Nicocodine B[footnote 1] 2/5[footnote 2]
Nicodicodine (6-nicotinoyldihydrocodeine) B[footnote 1] 2/5[footnote 2]
Nicomorphine (3,6-dinicotinoyl-morphine) A 2
Nifoxipam C 1
Nimetazepam C 4 Pt1
Nitrazepam C 4 Pt1
Nitrazolam C 1
Non-human chorionic gonadotrophin C 4 Pt2
Noracymethadol A 2
Norboletone C 4 Pt2
Norclostebol C 4 Pt2
Norcocaine A 2
Norcodeine B[footnote 1] 2/5[footnote 2]
Nordazepam C 4 Pt1
Norethandrolone C 4 Pt2
Norfludiazepam C 1
Norlevorphanol A 2
Normethadone A 2
Normorphine A 2
Norpethidine (4-Phenylpiperidine-4-carboxylic acid ethyl ester) A 1
Norpipanone A 2
O-Methyl-N-(α-methyl-3,4-methylenedioxyphenethyl)hydroxylamine A 1
Opium:    
Raw A 1
Prepared or medicinal A 2[footnote 6][footnote 7]
Oripavine C 2
Ovandrotone C 4 Pt2
Oxabolone C 4 Pt2
Oxandrolone C 4 Pt2
Oxazepam C 4 Pt1
Oxazolam C 4 Pt1
Oxycodone A 2
Oxymesterone C 4 Pt2
Oxymetholone C 4 Pt2
Oxymorphone A 2
Pemoline C 4 Pt1
Pentazocine B 3
Pentobarbital (Pentobarbitone) B 3
Pethidine (Meperidine) A 2
Phenadoxone A 2
Phenampromide A 2
Phenazepam (7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one) C 3
Phenazocine A 2
Phencyclidine (PCP) A 2
Phendimetrazine C 3
Phenmetrazine B[footnote 1] 2
Phenobarbital (Phenobarbitone) B 3
Phenomorphan A 2
Phenoperidine A 2
Phentermine C 3
Pholcodine (Morpholinylethylmorphine) B[footnote 1] 2/5[footnote 2]
Piminodine A 2
Pinazepam C 4 Pt1
Pipradrol C 3
Piritramide A 2
Poppy straw (and concentrate) A n/a
Prasterone (Dehydroepiandrosterone DHEA) C 4 Pt2
Prazepam C 4 Pt1
Pregabalin ((S)–3–(aminomethyl)-5-methylhexanoic acid) C 3
Probarbital (Probarbitone) B 3
Proheptazine A 2
Propallylonal B 3
Properidine (1-methyl-4-phenyl-piperidine-4-carboxylic acid isopropyl ester) A 2
Propetandrol C 4 Pt2
Propiram B 2/5[footnote 8]
Propylbenzoylecgonine A 2
Propylphenidate B 1
Prostanozol C 4 Pt2
Proxibarbital (Proxibarbitone) B 3
Psilocin A 1
Pyrazolam C 1
Pyrovalerone C 4 Pt1
Quinalbarbital (Quinalbarbitone/Secobarbital) B 2
Quinbolone C 4 Pt2
Racemethorphan A 2
Racemoramide A 2
Racemorphan A 2
Remifentanil A 2
Rolicyclidine A 1
Roxibolone C 4 Pt2
Secbutobarbital (Secbutobarbitone) B 3
Silandrone C 4 Pt2
Somatotropin C 4 Pt2
Somatrem C 4 Pt2
Somatropin C 4 Pt2
Stanolone C 4 Pt2
Stanozolol C 4 Pt2
Stenbolone C 4 Pt2
Sufentanil A 2
Talbutal B 3
Tapentadol A 2
Temazepam C 3
Tenocyclidine A 1
Testosterone C 4 Pt2
Tetrahydrocannabinol (Delta-THC) B 1
Tetrahydrogestrinone C 4 Pt2
Tetrazepam C 4 Pt1
Thebacon (acetyldihydrocodeinone) A 2
Thebaine A 2
Thiomesterone C 4 Pt2
Tilidine A 2
Tramadol C 3
Trenbolone C 4 Pt2
Triazolam C 4 Pt1
Trimeperidine A 2
U-47,700 A 1
Vinbarbital (Vinbarbitone) B 3
Vinylbital (Vinylbitone) B 3
Zaleplon C 4 Pt1
Zeranol C 4 Pt2
Zilpaterol C 4 Pt2
Zipeprol B 2
Zolpidem C 4 Pt1
Zopiclone C 4 Pt1
1-Androstenediol C 4 Pt2
1-Androstenedione C 4 Pt2
1-Benzylpiperazine (BZP) C 1
1-(Benzofuran-5-yl)-propan-2-amine (5-APB) B 1
1-(Benzofuran-6-yl)-propan-2-amine (6-APB) B 1
1-Benzyl-4-methylpiperazine (BZMP) C 1
1,4-Butanediol (1,4-BD) (for human ingestion) B n/a[footnote 9]
1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine (CPCPP) C 4 Pt1
1-(3-Chlorophenyl)piperazine (mCPP) C 4 Pt1
1-(4-Chlorophenyl)piperazine (pCPP) C 1
1-Cyclohexyl-4-(1,2-diphenylethyl)piperazine (MT-45) A 1
1,4-Dibenzylpiperazine (DBZP) C 1
1-(2,3-Dihydro-1-benzofuran-5-yl)-propan-2-amine (5-APDB) B 1
1-(2,3-Dihydro-1-benzofuran-6-yl)-propan-2-amine (6-APDB) B 1
1-(4-Fluorophenyl)piperazine (pFPP) C 1
1-(5-Fluoropentyl)-3-(4-methyl-naphthoyl)indole (MAM-2201) B 1
1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole (AM-694) B 1
1-(5-Fluoropentyl)-3-(naphthalen-1-oyl)indole (AM-2201) B 1
1-Methyl-4-phenylpiperidine-4-carboxylic acid A 2
1-(3,4-Methylenedioxybenzyl)butyl(ethyl)amine A 1
1-(3,4-Methylenedioxybenzyl)butyl(methyl)amine A 1
1-(3-Methylphenyl)piperazine (mMPP) C 1
1-(4-Methoxyphenyl)piperazine (pMeOPP) C 1
1-[1-(3-Methoxyphenyl)cyclohexyl]-piperidine (3-MeO-PCP) B 1
1-[1-(4-Methoxyphenyl)cyclohexyl]-piperidine (4-MeO-PCP) B 1
1-(4- Methylphenyl)piperazine (pMPP) C 1
1-Pentyl-3-(2-iodobenzoyl)indole (AM-679) B 1
1-Pentyl-3-(2,2,3,3-tetramethylcyclopropylcarbonyl)indole (UR-144) B 1
1-(3-Trifluoromethylphenyl)piperazine (TFMPP) C 1
2-Amino-1-(2,5-dimethoxy-4-methylphenyl)ethanol A 1
2-Amino-1-(3,4-dimethoxyphenyl)ethanol A 1
2-(4-Bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl] ethanamine (25B-NBOMe) A 1
2-Chloro-6-fluorophenethylamine A 1
2-(4-Chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) A 1
2-(1,4-Dimethoxy-2-naphthyl)ethylamine A 1
2-(1,4-Dimethoxy-2-naphthyl)-1-methylethylamine A 1
2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)ethylamine A 1
2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)-1-methylethylamine A 1
2-(2,5-Dimethoxy-4-methylphenyl)cyclopropylamine A 1
2,5-Dimethoxy-4-(N)-propylthiophenethylamine (2C-T-7) A 1
2-(3,4-Dimethoxyphenyl)ethylamine (Homoveratrylamine) A 1
2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)ethylamine A 1
2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)-1-methylethylamine A 1
2,4-Dichlorophenethylamine A 1
2,4-Dimethylazetidinyl{(6aR,9R)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinolin-9-yl}methanone (LSZ) A 1
2,5-Dimethoxy-4-Bromoamphetamine A 1
2,5-Dimethoxy-4-Iodoamphetamine A 1
2,5-Dimethoxy-4-Methylamphetamine A 1
2,5-Dimethoxy--4-dimethylphenethylamine A 1
2,5-Dimethoxy-4-iodoamphetamine A 1
2-(2,5-Dimethoxy-4-methylphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25D-NBOMe) A 1
2-((Dimethylamino)methyl)-1-(3-hydroxyphenyl)cyclohexanol (O-Desmethyltramadol) B 1
2,6-Dichlorophenethylamine A 1
2-Diphenylmethylpyrrolidine B 1
2-(Ethylamino)-2-(3-methoxyphenyl)cyclohexanone (Methoxetamine) B 1
2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe) A 1
2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)ethylamine A 1
2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)-1-methylethylamine A 1
2-(5-Methoxy-2-methyl-2,3-dihydrobenzo[β]furan-6-yl)-1-methylethylamine A 1
2-(5-Methoxy-2,2-dimethyl-2,3-dihydrobenzo[β]furan-6-yl)-1-methylethylamine A 1
2-(α-Methyl-3,4-methylenedioxyphenethylamino)ethanol A 1
2-Methoxyethyl(α-methyl-3,4-methylenedioxyphenethyl)amine A 1
2-(2-Methoxyphenyl)-2-(methylamino)cyclohexanone B 1
2-Methyl-3-morpholino-1,1-diphenylpropane-carboxylic acid A 2
2-Methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one (butylone) B 1
2-Methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (methylone) B 1
β,2,5-Trimethoxy-4-methylphenethylamine A 1
3,4-Dichloro-N-[[1-(dimethylamino)cyclohexyl]methyl]benzamide (AH-7921) A 1
3-Fluoromethcathinone (3-FMC) B 1
3-Hydroxyphenazepam C 1
3-Hydroxy-4-methoxyphenethylamine A 1
3-Hydroxy-5α-androstan-17-one C 4 Pt2
3-Methoxy-4-ethoxy-α-methylphenethylamine A 1
3-Methoxy-4-Hydroxyamphetamine A 1
3-Methoxy-4-Hydroxymethamphetamine A 1
3-Methoxy-4-Hydroxyphenethylamine A 1
3-Methylfentanyl A 1
3,4-Dichloroethylphenidate B 1
3,4-Dichloromethylphenidate B 1
3,4-Dichlorophenethylamine A 1
3,4-Dimethoxyamphetamine A 1
3,4-Dimethoxyphenethylamine A 1
3,4-Methylenedioxy-N,N-dimethylamphetamine A 1
(3,4-Methylenedioxymethamphetamine, MDMA) A 1
β,3,4,5-Tetramethoxyphenethylamine A 1
4-Androstene-3, 17-dione C 4 Pt2
4-Bromo-2,5-dimethoxy-α-methylphenethylamine A 1
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) A 1
4-Bromo-β,2,5-trimethoxyphenethylamine A 1
4-Bromo-2,5-dimethoxy--methylphenethylamine A 1
4’-Chlorodiazepam C 1
4-Chloro-2,5-dimethoxyphenethylamine (2C-C) A 1
4-Chloromethandienone C 4 Pt2
4-Cyano-1-methyl-4-phenylpiperidine A 2
4-Cyano-2-dimethylamino-4,4-diphenylbutane A 2
4-Fluoroethylphenidate B 1
4-Fluoromethylphenidate B 1
4-Hydroxy-3-methoxyphenethylamine (HMMA) A 1
4-Iodo-2,5-dimethoxy-α-methylphenethyl(dimethyl)amine A 1
4-Methyl-aminorex A 1
4-Methylmethcathinone (Mephedrone) B 1
4-Methylmethylphenidate B 1
4-Methylthioamphetamine (α-Methyl-4-methylthio)phenethylamine A 1
4-Methoxymethcathinone (bk-PMMA/methedrone) B 1
4-Methyl-5-(4-methylphenyl)-4,5-dihydrooxazol-2-amine (4,4’-DMAR) A 1
5-(2-Aminopropyl)indole (5-IT) B 1
5-Androstenedione C 4 Pt2
5α-Androstane-3,17-diol C 4 Pt2
5-Androstene-3,17-diol C 4 Pt2
5-Methoxydimethyltryptamine (5-MeO-DMT) A 1
(6aR,9R)-4-Acetyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (ALD-52) A 1
6-(2-Aminopropyl)indole (6-IT) B 1
(6aR,9R) R,9R)-N,N-diethyl-7-allyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (AL-LAD) A 1
(6aR,9R) R,9R)-N,N-diethyl-7-propyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (PRO-LAD) A 1
(6aR,9R) R,9R)-N,N-diethyl-7-ethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (ETH-LAD) A 1
6-β-Hydroxytestosterone C 4 Pt2
14-Hydroxymorphine A 2
19-Norandrostenedione C 4 Pt2
19-Norandrosterone C 4 Pt2
19-Noretiocholanolone C 4 Pt2
19-Nor-5-Androstene-13,17-diol C 4 Pt2
19-Nor-4-Androstene-3,17-dione C 4 Pt2
  1. Falls within paragraph 6 of Part I of Schedule 2 of the MDA 1971 (ie Class A) if in a preparation designed for administration by injection.  2 3 4 5 6 7 8 9 10 11

  2. Falls within Schedule 5 if any preparation of one or more of the substances to which this note applies, not being a preparation designed for administration by injection, when compounded with one or more other active or inert ingredients and containing a total of not more than 100 milligrams of the substance or substances (calculated as base) per dosage unit or with a total concentration of not more than 2.5 percent (calculated as base) in undivided preparations.  2 3 4 5 6 7 8

  3. On 1 November 2018, Cannabis-based products for medicinal use in humans (CBPMs) were introduced under Schedule 2 to the Misuse of Drugs Regulations 2001. Only products meeting the definition of a CBPM in regulation 2(1) of the Misuse of Drugs Regulations 2001 were rescheduled. Products not meeting this definition (other than cannabis-based medicines that have received marketing authorisation and have been separately scheduled) have remained in Schedule 1 which means they cannot be accessed except under a Home Office licence. 

  4. “Sativex” is the first cannabis-based medicine (oral spray) recognised in the UK to have medicinal properties. Following marketing authorisation, the ACMD recommended that “Sativex” should be placed in Part I of Schedule 4 to the 2001 Regulations. 

  5. Falls within Schedule 5 if in a preparation designed for oral administration, containing not more than 135 mg of dextropropoxyphene (calculated as base) per dosage unit or with a concentration of not more than 2.5 percent (calculated as base) in undivided preparations. 

  6. Falls within Schedule 5 if in any preparation of difenoxin containing, per dosage unit, not more than 0.5 mg of difenoxin and a quantity of atropine sulphate equivalent to at least 5 percent of the dose of difenoxin. 

  7. Falls within Schedule 5 if in any preparation of diphenoxylate containing, per dosage unit, not more than 2.5 mg of diphenoxylate calculated as base, and a quantity of atropine sulphate equivalent to at least 1 percent of the dose of diphenoxylate. 

  8. GBL and 1,4-BD are not inserted into any Schedule to the 2001 Regulations. Instead, because of their legitimate industrial uses, regulation 4B of the 2001 Regulations makes it lawful to import, export, produce, supply, offer to supply or possess these substances except where a person does so knowing or believing that they will be used for the purpose of human ingestion.  2

  9. Falls within Schedule 5 if in a preparation of medicinal opium or morphine containing (in either case) not more than 0.2 percent of morphine calculated as anhydrous morphine base, being a preparation compounded with one or more other active or inert ingredients in such a way that the opium or, as the case may be, the morphine, cannot be recovered by readily applicable means or in a yield which would constitute a risk to health.  2

  10. Falls within Schedule 5 if in any powder of ipecacuanha and opium comprising: 10 percent opium, in powder, 10 percent ipecacuanha root, in powder, well mixed with 80 percent of any other powdered ingredient containing no controlled drug. 

  11. Falls within Schedule 5 if in a preparation containing, per dosage unit, not more than 100 mg of propiram calculated as base and compounded with at least the same amount (by weight) of methylcellulose.