Guidance

EAGA guidance on HIV post-exposure prophylaxis

Updated guidance on occupational HIV post-exposure prophylaxis (PEP) from the UK Chief Medical Officers' Expert Advisory Group on AIDS (EAGA).

• From: Department of Health and Social Care
• Published: 19 September 2008
• Last updated: 29 April 2015 — See all updates

Documents

Change to recommended regimen for post-exposure prophylaxis (PEP)

PDF, 21.6 KB, 2 pages

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Recommendation for HIV post-exposure prophylaxis (PEP) following occupational exposure to a source with undetectable HIV viral load

PDF, 72.1 KB, 1 page

HIV post-exposure prophylaxis: guidance from the UK Chief Medical Officers' Expert Advisory Group on AIDS (2008)

PDF, 439 KB, 75 pages

Details

Page updated 29 April 2015

The advice in the HIV window period (November 2014) statement replaces the advice in the PEP guidance with regards to the recommended follow-up schedule (pages 21-23 of the PEP guidance). A fourth generation serological test should be performed 4 weeks after the exposure event (deferred to 4 weeks from when the PEP course was completed). The need for an 8-week test following an occupational exposure incident should be determined by a risk assessment on a case-by-case basis.

The 2008 guidance is the latest publication from EAGA on HIV PEP following occupational exposure.

EAGA has supplemented this with separate advice on:

• a change to the recommended regimen for post-exposure prophylaxis (PEP) (September 2014)
• the need for PEP following occupational exposure to a source with undetectable viral load (December 2013)

All 3 documents and the HIV window period (November 2014) statement should be read in conjunction with local policy on managing incidents in occupational settings where workers are accidentally exposed to blood or body fluids.

Published 19 September 2008
Last updated 29 April 2015 + show all updates

1. 29 April 2015

   update to the post-exposure prophylaxis (PEP) guidance

2. 8 September 2014

   Added an update on the change to recommended regimen for post-exposure prophylaxis (PEP)

3. 24 January 2014

   Updated advice regarding the need for PEP following occupational injuries resulting from needles, syringes and other sharp instruments contaminated with HIV.

4. 19 September 2008

   First published.