Freedom of Information request on mixing COVID-19 vaccines (FOI 21/1024)
Published 25 February 2022
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This publication is available at https://www.gov.uk/government/publications/freedom-of-information-responses-from-the-mhra-week-commencing-20-september-2021/freedom-of-information-request-on-mixing-covid-19-vaccines-foi-211024
22nd September 2021
FOI 21/1024
Dear
Thank you for your email.
The Information for Healthcare Professionals and Summary of Product Characteristics clearly states that the vaccines cannot be mixed between the first and second doses. This is not because they are necessarily dangerous, but because there is not enough data available on the administration of different vaccines for the first and second doses.
We also do not hold any data on the administration of a second dose of vaccine 7 months after the first dose. This is outside of the instructions in the Information for Healthcare Professionals and Summary of Product Characteristics.
Unfortunately, we are unable to provide medical advice on individual cases, so I would encourage you to discuss any concerns with your doctor or pharmacist, who will be in the best position to advise you. It is a key role of the MHRA to provide doctors with advice on the safe use of medicines; however, the final responsibility for the clinical care of the patient remains with the doctor given their clinical expertise and knowledge of your medical history.
With reference to your further questions we are able to provide the following:
I urgently need below data for vaccine mixing I had AstraZeneca for first dose 7 months ago and then got scared now I want to have second dose of Pfizer can you tell me how many cases of adverse outcome when second dose was Pfizer ?
We are unable to provide details on adverse reactions which occurred after mixed vaccines as we intend to publish this. As we plan to publish the data, we consider that your request is covered by Section 22 of the Freedom of Information Act (information intended for future publication).
Could you please provide how many cases of blood clots were found in those after their MRNA second dose ?
This information can be found in our weekly summary of Yellow Card reporting which can be found at the following link:
Coronavirus vaccine - weekly summary of Yellow Card reporting - GOV.UK (www.gov.uk)
How many of people died who took mixed vaccine ?
Death statistics are not held by the MHRA and as such we would advise you to contact the Office for National Statistics Contact us - Office for National Statistics (ons.gov.uk) or Public Health England at enquiries@phe.gov.uk
How many experienced serious side effects or neurological condition ?
This information is held in the Vaccine Analysis Prints which can be found in the weekly summary of Yellow Card reporting linked above. For data concerning reactions after the second dose, this is intended for future publication and as such is exempt under Section 22 of the Freedom of Information Act.
How many had heart inflammation ?
This information is held in the Vaccine Analysis Prints which can be found in the weekly summary of Yellow Card reporting linked above. For data concerning reactions after the second dose, this is intended for future publication and as such is exempt under Section 22 of the Freedom of Information Act.
If you have a query about the information provided, please reply to this email
If you are dissatisfied with the handling of your request, you have the right to ask for an internal review. Internal review requests should be submitted within two months of the date you receive this response and addressed to: info@mhra.gov.uk
Due to the ongoing Covid-19 situation, we are not able to accept delivery of any documents or correspondence by post or courier to any of our offices
Please remember to quote the reference number above in any future communications.
If you were to remain dissatisfied with the outcome of the internal review, you would have the right to apply directly to the Information Commissioner for a decision. Please bear in mind that the Information Commissioner will not normally review our handling of your request unless you have first contacted us to conduct an internal review. The Information Commissioner can be contacted at:
Information Commissioner’s Office
Wycliffe House
Water Lane
Wilmslow
Cheshire
SK9 5AF
Yours sincerely
MHRA Customer Service Centre
Medicines and Healthcare products Regulatory Agency 10 South Colonnade, Canary Wharf, London E14 4PU