Freedom of Information request on the number of amplification cycles testing cycles were instructed to do in November 2020 and March 2021 (FOI 21-584)
Published 13 August 2021
8th June 2021 FOI 21/584
Dear
Thank you for your information request, dated 28/05/2021, where you asked for ‘How many amplification cycles were testing Labs in the UK instructed to do in November 2020? And how many cycles were they doing in March 2021 ?
Has the number of amplification cycles ever changed during the years 2020 and 2021 ?’
I can confirm that we do not have access to the information that you have requested and it is likely that it will vary between laboratories depending on the instructions for use of the different assays that they use. You may wish to direct this FOI request to NHS Test and Trace who should be able to confirm this.
You may find the distribution of CT values in figure S6 of the following manuscript infectivity_manuscript_20210119_with_figures (ox.ac.uk) useful, as they seem to suggest that small changes to the upper cut-off value will have little overall effect on the number of patients diagnosed with COVID. The vast majority of patients within this example have CT values of <30, with very few >35.
If you have any queries, please reply to this email.
If you are dissatisfied with the handling of your request, you have the right to ask for an internal review.
Internal review requests should be submitted within two months of the date you receive this response and addressed to: info@mhra.gov.uk .
Please remember to quote the reference number above in any future communications. Please note, due to the ongoing Covid-19 situation, we are not able to accept delivery of any documents or correspondence by post or courier to any of our offices.
If you were to remain dissatisfied with the outcome of the internal review, you would have the right to apply directly to the Information Commissioner for a decision. Please bear in mind that the Information Commissioner will not normally review our handling of your request unless you have first contacted us to conduct an internal review. The Information Commissioner can be contacted at:
Information Commissioner’s Office Wycliffe House Water Lane Wilmslow Cheshire SK9 5AF
Yours sincerely,
MHRA Customer Service Centre
Medicines and Healthcare products Regulatory Agency 10 South Colonnade, Canary Wharf, London E14 4PU