Non-tech. summaries 2014: projects on human cancer
Projects granted during 2014 that have a primary purpose of translational and applied research: human cancer.
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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of translational and applied research: human cancer.
The following projects were granted:
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radiosensitisation of bladder tumours and normal tissues (bladder cancer, radiotherapy, radiosensitisation, normal tissue effects, orthotopic bladder model)
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using mechanical stimuli to move therapies into tumours and vaccines across the skin (tumour, vaccine, mechanical, delivery, ultrasound)
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virus based therapies in preclinical cancer models (adenovirus, cancer, oncolytic)
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in-house service production monoclonal antibodies (monoclonal antibodies, infections, disease, diagnostics, vaccination)
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engineering immunity to cancer (genetic modification, T-cells, cancer, therapy)
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the isolation of novel antibody therapeutics for the treatment of human disease (antibody, cartilaginous fish, therapeutic drug)
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molecular basis and theory of gynaecological cancer (ovarian cancer, gynaecological cancer, immunotherapy, chemotherapy)
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developing selective, novel cancer therapeutics (cancer, drug discovery, therapeutics, preclinical)
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targeting cancer stem cells and their micro environment (cancer stem cells, pancreatic cancer)
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imaging in drug discovery (non-invasive, medical imaging, drug discovery)
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the cause of resistance to treatment in human blood cancers (blood cancers, resistance, genome-damage)
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experimental cancer diagnosis and therapy (cancer, tumour, diagnosis, therapy, models)
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protecting stem cell and tissue function (stem cells, ageing, drug development, regeneration, mucositis)
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nanomedicine based drug delivery (nanotechnology, drug development, brain diseases, biologics)
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development of novel agents for cancer therapy (cancer, novel drugs)
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development of personalised anti-cancer strategies (cancer, drugs, translation, biomarkers, metastasis)
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micro environment signalling in cancer (cancer, micro environment, therapy)
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novel multifunctional phage for guided systemic cancer gene therapy
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evaluation of anti-cancer drugs (cancer, drugs)
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epithelial-stromal interaction in cancer (cancer, stroma, epithelium, breast, lung)
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biology of relapsed childhood leukaemia (leukaemia, drug-resistance, relapse, bone marrow micro environment)
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immunisation of rodents (immunise antigens antibodies)