Non-tech. summaries 2015: projects on the musculoskeletal system
Projects granted during 2015 that have a primary purpose of basic research: musculoskeletal system.
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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2015 with a primary purpose of basic research: musculoskeletal system.
The following projects were granted:
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inflammation and cancer-induced bone disease therapy (bone, inflammation, ankylosing spondylitis, osteoporosis, cancer)
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accelerating fracture and cutaneous wound healing (fracture, bone, wound, skin, healing)
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nutrition, insulin resistance and grazing in ponies (nutrition, insulin resistance, grazing)
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microvesicles and the prevention of tissue wasting (microvesicles, stem cells, aging, tissue wasting)
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understanding and treatment of neuromuscular conditions (neuromuscular disease; muscular dystrophy; skeletal muscle; stem cells)
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the mechanics and energetics of locomotion (flight, running, bird, muscle, energetic)
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homeostatic calcium regulation in fish (Ca2+, scales, blood, freshwater, seawater)
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the role of muscle stem cells in health and disease (stem cell, skeletal muscle, regeneration)
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the safety and efficacy of cell therapies (stem cells, pre-clinical testing, medicinal products)
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pre-clinical analysis of therapies for neuromuscular diseases (muscular dystrophy; therapy development)
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in vivo models for tissue engineering (stem cells, growth factors, scaffold, tissue engineering, regenerative medicine)
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new biomaterials for healing of bone defects (synthetic material, bioactivity, bone, regeneration)
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purinergic signalling, bone cell function and tissue calcification (vascular calcification, osteoporosis, loading, bone)
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angiogenesis in health and disease (capillaries, blood flow, skeletal muscle, ischaemia, hypoxia)
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models of tissue repair and reconstruction in the limb (injury, limb, repair, reconstruction, regeneration)
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understanding muscle maintenance, regeneration and ageing (muscle, regeneration, inflammation, muscular dystrophy, stem cells, duchenne muscular dystrophy)
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manipulation of signalling pathways in zebrafish (zebrafish, HSPG, regeneration)
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genetic and hormonal regulation of the skeleton (osteoporosis, osteoarthritis, fracture, genetics, hormones)
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musculoskeletal tissue regeneration (musculoskeletal, regeneration, repair, bone, cartilage)