Research and analysis

NOIDs causative agents: week 20 (week ending 22 May 2022)

Updated 16 January 2023

NOIDs weekly report

Laboratories in England have a statutory duty to notify the UK Health Security Agency of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • Carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia lamblia
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Hepatitis D
  • Hepatitis E
  • Influenza virus
  • Junin virus
  • Kyasanur
  • Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • Measles virus
  • Mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium Knowlesi
  • Plasmodium Malariae
  • Plasmodium Ovale
  • Plasmodium Vivax
  • Polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS Coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile Virus
  • Yellow fever virus
  • Yersinia pestis
Week notification received 2022/15 2022/16 2022/17 2022/18 2022/19 2022/20
Bacillus            
Bacillus cereus 18 28 15 28 16 14
Bordetella            
Bordetella pertussis 1 2 4 1 - -
Borrelia            
Borrelia burgdorferi 12 9 9 14 12 10
Borrelia sp - 1 1 1 2 -
Borrelia tillae 1 2 - - - -
Campylobacter            
Campylobacter coli 42 12 19 18 20 23
Campylobacter fetus - - - - 2 2
Campylobacter jejuni 202 195 301 198 259 276
Campylobacter lari - - 1 - - 1
Campylobacter other named 2 - - - - 1
Campylobacter sp 777 547 823 638 872 1182
Campylobacter upsaliensis - - 1 - 1 -
Campylobacter ureolyticus (bacteroides corrodens) - 1 - 2 1 1
Chikungunya virus            
Chikungunya virus 1 - - 1 1 -
Clostridium            
Clostridium perfringens 31 28 25 41 35 25
Coronavirus            
Coronavirus 90 60 56 49 66 50
Human coronavirus 229e 1 1 2 - - -
Human coronavirus hku1 1 - - - 1 -
SARS coronavirus - - 1 - - -
SARS-CoV-2 antibody indeterminate 144 87 173 75 98 114
SARS-CoV-2 antibody void 44 35 17 70 72 36
SARS-CoV-2 coronavirus (covid- 19) 162,212 109,885 70,575 61,614 52,619 42,736
SARS-CoV-2 coronavirus (covid- 19) indeterminate 1,634 1,240 1,212 1,040 850 912
SARS-CoV-2 IgG antibody negative 1,084 851 809 750 566 658
SARS-CoV-2 IgG antibody positive 2,989 2,726 2,496 2,084 2,073 1,908
SARS-CoV-2 IgM antibody negative 14 24 13 8 30 13
SARS-CoV-2 IgM antibody positive 11 7 4 2 10 2
SARS-CoV-2 total antibody negative 1,275 1,039 1,051 710 1,189 681
SARS-CoV-2 total antibody positive 3,601 3,537 3,511 2,193 2,680 2,089
Corynebacterium            
Corynebacterium diphtheriae - - 3 - 4 -
Corynebacterium ulcerans 1 - - - - -
Coxiella            
Coxiella burnetii - - 1 - - 1
Cryptosporidium            
Cryptosporidium hominis 2 2 3 - - -
Cryptosporidium parvum 26 34 85 50 36 19
Cryptosporidium sp 28 30 34 27 20 54
Entamoeba            
Entamoeba histolytica - - 2 1 1 -
Escherichia            
Escherichia coli O 157 11 6 11 3 9 7
Flaviviruses            
Dengue virus - - - 2 2 -
Giardia            
Giardia lamblia - - - - 2 1
Haemophilus            
Haemophilus influenzae 42 31 70 40 33 46
Hepatitis viruses            
Hepatitis A 16 12 11 6 15 12
Hepatitis B 218 177 175 201 231 159
Hepatitis C 352 375 268 312 295 344
Hepatitis D 1 3 3 2 6 3
Hepatitis E 33 21 19 29 28 33
Influenza virus            
Influenza A 1,126 761 643 554 519 379
Influenza B 44 13 32 16 28 25
Influenza indeterminate - - 6 - - 1
Influenza ungrouped 46 18 12 8 3 12
Legionella            
Legionella longbeachae - - - 1 - -
Legionella other named - - - 1 - -
Legionella pneumophila 3 1 10 2 2 6
Legionella sp 2 2 1 - 3 1
Listeria            
Listeria monocytogenes 5 4 1 4 1 2
Mycobacterium            
Mycobacterium tuberculosis 65 63 66 56 56 56
Neisseria            
Neisseria meningitidis 12 11 6 12 6 19
Paramyxoviruses            
Measles virus - 1 1 - - -
Mumps virus 2 1 2 2 2 -
Plasmodium            
Plasmodium falciparum - 2 4 2 - 1
Plasmodium ovale - - 1 - - -
Polyomavirus            
Polyomavirus BK 37 24 34 23 36 38
Polyomavirus JC 9 1 4 1 6 2
Rickettsia            
Rickettsia sp - - - 1 - -
Rickettsia spotted fever - - - 1 - -
Rubella virus            
Rubella virus 6 4 7 1 - 4
Salmonella            
Other salmonellas 38 47 49 50 25 16
Salmonella diarizonae 6 - - - - -
Salmonella enteritidis 21 17 41 23 15 8
Salmonella infantis 5 5 8 - - -
Salmonella mbandaka 5 - - - - -
Salmonella newport 7 6 - - - -
Salmonella oranienburg - - 6 6 - -
Salmonella sp 16 13 23 25 60 139
Salmonella typhi and paratyphi 21 10 17 19 8 18
Salmonella typhimurium 32 29 30 31 15 21
Shigella            
Shigella boydii 5 - 1 - 4 1
Shigella dysenteriae 1 2 1 1 - -
Shigella flexneri 14 13 21 13 11 13
Shigella sonnei 12 12 24 13 19 18
Shigella sp 37 22 56 38 38 55
Streptococcus            
Streptococcus group A 47 45 76 52 58 50
Streptococcus pneumoniae 119 111 96 95 80 60
Vibrio            
Vibrio cholerae 3 1 - 2 - 2

Carbapenemase-producing Enterobacterales (CPE)*

Please note: The numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2022/15 2022/16 2022/17 2022/18 2022/19 2022/20
Citrobacter              
Citrobacter spp NDM - 1 1 - - -
  OXA48 1 2 - - 1 -
Enterobacter              
Enterobacter cloacae complex IMP - 1 1 - - -
  KPC 2 1 - 1 3 -
  NDM - - 2 - 1 -
  OXA48 - 1 1 - - -
Escherichia              
Escherichia coli KPC 2 3 2 1 - -
  NDM 4 3 6 1 3 2
  OXA48 7 4 7 1 6 1
Klebsiella              
Klebsiella aerogenes OXA48 - - - - - 1
Klebsiella oxytoca OXA48 - - 1 - - -
Klebsiella pneumoniae IMP - - - 1 - -
  KPC 4 1 2 3 2 1
  NDM 4 2 3 1 1 3
  OXA48 7 2 5 3 5 1
  VIM - 1 - - - -
  Other 1 - 1 - 1 1
Leclercia              
Leclercia adecarboxylata KPC - - - 1 - -

Other carbapenemase-producing Gram-negative organisms*

Please note: The numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2022/15 2022/16 2022/17 2022/18 2022/19 2022/20
Acinetobacter              
Acinetobacter baumannii IMP - - - - - 1
Pseudomonas              
Pseudomonas aeruginosa IMP 1 1 1 - - 1
  NDM - - - 1 - -
  Other - 2 - 1 2 -
Pseudomonas putida group Other - - - 1 - -
Other pseudomonas spp Other - 1 - - - -

*for all Carbapenemase-producing Gram-negative organisms, the reports are de- duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.