Research and analysis
NOIDs causative agents: week 29 (week ending 21 July 2024)
Updated 20 December 2024
Applies to England and Wales
© Crown copyright 2024
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Laboratories in England have a statutory duty to notify the UK Health Security Agency of the identification of the following causative agents:
- Bacillus anthracis
- Bacillus cereus
- Bordetella pertussis
- Borrelia spp
- Brucella spp
- Burkholderia mallei
- Burkholderia pseudomallei
- Campylobacter spp
- Carbapenemase-producing Gram-negative bacteria
- Chikungunya virus
- Chlamydophila psittaci
- Clostridium botulinum
- Clostridium perfringens
- Clostridium tetani
- Corynebacterium diphtheriae
- Corynebacterium ulcerans
- Coxiella burnetii
- Crimean-Congo haemorrhagic fever virus
- Cryptosporidium spp
- Dengue virus
- Ebola virus
- Entamoeba histolytica
- Escherichia coli O 157
- Francisella tularensis
- Giardia lamblia
- Guanarito virus
- Haemophilus influenzae (invasive)
- Hanta virus
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Influenza virus
- Junin virus
- Kyasanur Forest disease virus
- Lassa virus
- Legionella spp
- Leptospira interrogans
- Listeria monocytogenes
- Machupo virus
- Marburg virus
- Measles virus
- Mpox virus
- Mumps virus
- Mycobacterium tuberculosis complex
- Neisseria meningitidis
- Omsk haemorrhagic fever virus
- Plasmodium falciparum
- Plasmodium Knowlesi
- Plasmodium Malariae
- Plasmodium Ovale
- Plasmodium Vivax
- Polio virus
- Rabies virus
- Rickettsia spp
- Rift Valley fever virus
- Rubella virus
- Sabia virus
- Salmonella spp
- SARS Coronavirus
- Shigella spp
- Streptococcus group A (invasive)
- Streptococcus pneumoniae (invasive)
- Varicella zoster virus
- Variola virus
- Vibrio cholerae
- West Nile virus
- Yellow fever virus
- Yersinia pestis
Statutory notifications of causative agents, grouped by root organism
Totals for the current week compared to the previous 5.
| Week notification received | 2024/24 | 2024/25 | 2024/26 | 2024/27 | 2024/28 | 2024/29 |
|---|---|---|---|---|---|---|
| Arboviruses | ||||||
| West Nile Virus | - | - | - | 1 | - | - |
| Bacillus | ||||||
| Bacillus cereus | 22 | 13 | 18 | 32 | 21 | 20 |
| Bordetella | ||||||
| Bordetella pertussis | 500 | 360 | 302 | 228 | 193 | 233 |
| Borrelia | ||||||
| Borrelia burgdorferi | 24 | 46 | 34 | 35 | 41 | 34 |
| Borrelia sp | 6 | 1 | 6 | 6 | 7 | 8 |
| Brucella | ||||||
| Brucella melitensis | 1 | - | 1 | 1 | - | - |
| Brucella sp | - | 5 | 1 | 1 | - | 4 |
| Campylobacter | ||||||
| Campylobacter coli | 35 | 53 | 45 | 51 | 48 | 47 |
| Campylobacter curvus | - | - | - | - | - | 1 |
| Campylobacter fetus | - | - | - | 1 | - | 1 |
| Campylobacter jejuni | 362 | 363 | 397 | 335 | 318 | 243 |
| Campylobacter lari | 3 | 3 | 2 | - | - | - |
| Campylobacter other named | - | - | - | 2 | 1 | 1 |
| Campylobacter rectus | 1 | - | - | - | - | - |
| Campylobacter sp | 1,455 | 1,468 | 1,393 | 1,424 | 1,246 | 1,354 |
| Campylobacter upsaliensis | 1 | 1 | - | 1 | 1 | 1 |
| Campylobacter ureolyticus (bacteroides corrodens) | - | - | - | 1 | 3 | - |
| Chikungunya virus | ||||||
| Chikungunya virus | - | - | 1 | 1 | 1 | 1 |
| Clostridium | ||||||
| Clostridium perfringens | 40 | 35 | 30 | 42 | 31 | 28 |
| Coronavirus | ||||||
| Coronavirus | 60 | 60 | 43 | 44 | 36 | 43 |
| Human coronavirus 229e | - | - | - | - | 1 | - |
| SARS coronavirus | - | - | - | - | 3 | - |
| SARS-CoV-2 antibody indeterminate | 93 | 140 | 79 | 55 | 38 | 119 |
| SARS-CoV-2 antibody void | 6 | - | 2 | - | - | - |
| SARS-CoV-2 coronavirus (COVID-19) | 2,277 | 3,124 | 3,328 | 3,027 | 3,439 | 3,953 |
| SARS-CoV-2 coronavirus (COVID-19) indeterminate | 52 | 56 | 89 | 59 | 68 | 117 |
| SARS-CoV-2 IgG antibody negative | 58 | 21 | 13 | 9 | 20 | 23 |
| SARS-CoV-2 IgG antibody positive | 371 | 131 | 103 | 151 | 98 | 122 |
| SARS-CoV-2 total antibody negative | 30 | 20 | 16 | 6 | 24 | 25 |
| SARS-CoV-2 total antibody positive | 52 | 56 | 58 | 66 | 86 | 82 |
| Corynebacterium | ||||||
| Corynebacterium diphtheriae | 3 | - | - | - | - | 3 |
| Corynebacterium ulcerans | - | - | 1 | - | 1 | - |
| Coxiella | ||||||
| Coxiella burnetii | 1 | - | - | - | - | - |
| Cryptosporidium | ||||||
| Cryptosporidium cuniculus | - | - | - | 1 | - | - |
| Cryptosporidium hominis | 14 | 12 | 16 | 11 | 17 | 7 |
| Cryptosporidium meleagridis | - | 2 | 2 | - | 1 | - |
| Cryptosporidium parvum | 47 | 45 | 41 | 37 | 46 | 17 |
| Cryptosporidium sp | 39 | 37 | 30 | 21 | 28 | 45 |
| Cryptosporidium ubiquitum | 1 | - | 1 | 1 | - | - |
| Entamoeba | ||||||
| Entamoeba histolytica | - | 2 | - | 2 | 1 | 1 |
| Escherichia | ||||||
| Escherichia coli O 157 | 14 | 23 | 18 | 11 | 13 | 8 |
| Flaviviruses | ||||||
| Dengue virus | 1 | 10 | 8 | 6 | 2 | 5 |
| Giardia | ||||||
| Giardia sp | 106 | 118 | 112 | 86 | 90 | 114 |
| Haemophilus | ||||||
| Haemophilus influenzae | 85 | 59 | 65 | 68 | 71 | 53 |
| Hepatitis viruses | ||||||
| Hepatitis A | 9 | 15 | 26 | 16 | 11 | 10 |
| Hepatitis B | 310 | 317 | 349 | 359 | 266 | 299 |
| Hepatitis C | 274 | 240 | 253 | 249 | 355 | 246 |
| Hepatitis D | 7 | 7 | 9 | 8 | 6 | 10 |
| Hepatitis E | 29 | 29 | 30 | 21 | 27 | 43 |
| Influenza virus | ||||||
| Influenza A | 124 | 144 | 236 | 220 | 277 | 327 |
| Influenza B | 70 | 63 | 128 | 126 | 161 | 172 |
| Influenza indeterminate | - | 1 | - | - | - | - |
| Influenza ungrouped | 7 | 2 | - | 3 | 1 | 6 |
| Legionella | ||||||
| Legionella longbeachae | 2 | - | - | 1 | 1 | - |
| Legionella other named | - | - | 1 | - | - | - |
| Legionella pneumophila | 6 | 8 | 4 | 9 | 6 | 14 |
| Legionella sp | 2 | 6 | 3 | 2 | 4 | - |
| Listeria | ||||||
| Listeria monocytogenes | 9 | 4 | 7 | 3 | 4 | 4 |
| Mycobacterium | ||||||
| Mycobacterium tuberculosis | 104 | 117 | 106 | 100 | 69 | 73 |
| Neisseria | ||||||
| Neisseria meningitidis | 36 | 23 | 13 | 12 | 23 | 14 |
| Orthopoxvirus | ||||||
| Mpox virus | 6 | 8 | 3 | 5 | 4 | 17 |
| Paramyxoviruses | ||||||
| Measles virus | 56 | 40 | 60 | 71 | 48 | 50 |
| Mumps virus | 6 | 5 | 4 | 9 | 6 | 8 |
| Plasmodium | ||||||
| Plasmodium falciparum | 6 | 2 | - | - | - | 1 |
| Plasmodium ovale | 5 | - | 1 | - | - | - |
| Plasmodium vivax | 6 | - | - | - | - | - |
| Polyomavirus | ||||||
| Polyomavirus BK | 39 | 56 | 45 | 52 | 45 | 74 |
| Polyomavirus JC | 7 | 7 | 6 | 7 | 8 | 15 |
| Polyomavirus untyped | 11 | 16 | 23 | 8 | 17 | 17 |
| Rickettsia | ||||||
| Rickettsia sp | - | - | - | 1 | - | - |
| Rickettsia spotted fever | - | 3 | 1 | - | - | - |
| Rickettsia tsutsugamushi | 1 | - | - | 1 | - | - |
| Rubella virus | ||||||
| Rubella virus | 1 | 1 | 2 | 2 | - | 3 |
| Salmonella | ||||||
| Other salmonellas | 63 | 73 | 60 | 75 | 69 | 34 |
| Salmonella agona | - | - | - | 6 | - | - |
| Salmonella bareilly | - | - | 6 | - | - | - |
| Salmonella chester | - | - | 5 | - | - | - |
| Salmonella enterica | - | - | - | 7 | - | - |
| Salmonella enteritidis | 75 | 85 | 77 | 85 | 56 | 33 |
| Salmonella heidelberg | - | - | - | 5 | - | - |
| Salmonella infantis | - | 6 | - | - | - | - |
| Salmonella java | - | 7 | - | - | - | - |
| Salmonella newport | 5 | 6 | 5 | 7 | 5 | - |
| Salmonella saint-paul | - | 6 | 9 | - | - | - |
| Salmonella sp | 13 | 35 | 36 | 31 | 84 | 189 |
| Salmonella stanley | - | - | 5 | - | - | - |
| Salmonella typhi and paratyphi | 12 | 15 | 9 | 15 | 10 | 9 |
| Salmonella typhimurium | 46 | 51 | 34 | 34 | 24 | 13 |
| Slmonella enterica | - | - | - | - | 5 | - |
| Shigella | ||||||
| Shigella boydii | - | 2 | - | 1 | 1 | 1 |
| Shigella dysenteriae | - | 1 | - | - | - | - |
| Shigella flexneri | 7 | 22 | 22 | 15 | 10 | 11 |
| Shigella sonnei | 27 | 32 | 21 | 12 | 22 | 18 |
| Shigella sp | 58 | 62 | 50 | 44 | 58 | 65 |
| Streptococcus | ||||||
| Streptococcus group A | 63 | 63 | 50 | 72 | 55 | 59 |
| Streptococcus pneumoniae | 88 | 104 | 99 | 94 | 78 | 82 |
| Vibrio | ||||||
| Vibrio cholerae | - | 1 | - | 1 | 1 | 1 |
Carbapenemase-producing Enterobacterales (CPE)
For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.
Note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2024/24 | 2024/25 | 2024/26 | 2024/27 | 2024/28 | 2024/29 | |
|---|---|---|---|---|---|---|---|
| Citrobacter | |||||||
| Citrobacter spp | IMP | 1 | 1 | - | - | - | - |
| KPC | 1 | 2 | - | 1 | 3 | - | |
| NDM | 1 | - | 2 | 2 | - | - | |
| OXA48 | 2 | 2 | 3 | 2 | 2 | - | |
| VIM | 1 | - | - | 3 | 1 | - | |
| Enterobacter | |||||||
| Enterobacter cloacae complex | IMP | 5 | 6 | 2 | 3 | 3 | - |
| KPC | 4 | 3 | 5 | 1 | 3 | 2 | |
| NDM | 5 | 2 | 6 | 5 | 6 | 3 | |
| OXA48 | 4 | 3 | 1 | 3 | 3 | - | |
| Other | - | 1 | 1 | 3 | - | - | |
| Enterobacter other named | NDM | 1 | - | - | - | - | - |
| Other enterobacter spp | IMP | - | 3 | - | 1 | - | - |
| NDM | - | 3 | 2 | 1 | 2 | - | |
| OXA48 | - | 1 | - | - | - | - | |
| VIM | 1 | 1 | - | - | 1 | - | |
| Escherichia | |||||||
| Escherichia coli | IMP | 4 | 6 | 4 | - | - | - |
| KPC | 8 | 13 | 7 | 8 | 12 | 6 | |
| NDM | 12 | 23 | 15 | 17 | 9 | 6 | |
| OXA48 | 24 | 15 | 24 | 18 | 21 | 4 | |
| VIM | 2 | - | 1 | 2 | 1 | - | |
| Other | 1 | 1 | 2 | 1 | 1 | - | |
| Klebsiella | |||||||
| Klebsiella aerogenes | IMP | - | - | 1 | - | - | - |
| KPC | - | 1 | - | 1 | - | - | |
| Klebsiella oxytoca | KPC | 1 | 1 | - | - | 1 | - |
| OXA48 | 2 | 2 | - | 2 | - | - | |
| VIM | - | - | 1 | - | 1 | - | |
| Klebsiella pneumoniae | IMP | 1 | 2 | 3 | - | 2 | - |
| KPC | 15 | 15 | 15 | 24 | 16 | 7 | |
| NDM | 6 | 12 | 10 | 10 | 5 | - | |
| OXA48 | 7 | 8 | 15 | 11 | 8 | 7 | |
| VIM | - | 2 | 2 | 3 | 1 | - | |
| Other | 1 | 3 | 2 | 2 | 2 | 1 | |
| Klebsiella variicola | KPC | - | 1 | - | - | 1 | - |
| OXA48 | - | - | 1 | - | - | - | |
| Other klebsiella spp | KPC | - | - | 1 | - | - | - |
| NDM | 1 | - | - | - | - | - | |
| OXA48 | 1 | - | 1 | - | 1 | - | |
| Proteus | |||||||
| Proteus mirabilis | NDM | 3 | 1 | - | 2 | - | - |
| OXA48 | - | 2 | - | - | - | - | |
| Other | 1 | - | - | 1 | - | - | |
| Serratia | |||||||
| Serratia marcescens/ureilytica | OXA48 | - | - | - | 1 | - | - |
Other carbapenemase-producing Gram-negative organisms
For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.
Note: the numbers presented here do not include specimens that have been referred to the Antimicrobial Resistance and Healthcare-Associated Infections (AMRHAI) Reference Unit.
| Week notification received | 2024/24 | 2024/25 | 2024/26 | 2024/27 | 2024/28 | 2024/29 | |
|---|---|---|---|---|---|---|---|
| Acinetobacter | |||||||
| Acinetobacter baumannii | NDM | - | - | - | - | 1 | - |
| Acinetobacter calcoaceticus/baumannii complex | NDM | - | - | - | 1 | - | - |
| Other acinetobacter spp | NDM | - | - | - | 1 | 1 | - |
| Pseudomonas | |||||||
| Pseudomonas aeruginosa | NDM | - | 1 | 2 | 2 | 1 | - |
| VIM | - | - | 1 | 3 | 1 | - | |
| Other | 1 | 1 | 2 | 1 | 1 | - | |
| Pseudomonas monteilli | VIM | - | 1 | - | - | 1 | - |
| Pseudomonas putida group | VIM | 1 | 1 | 1 | - | - | - |
| Other | 1 | - | - | - | - | - | |
| Other pseudomonas spp | VIM | - | 1 | - | - | - | - |
| Other | |||||||
| NDM | - | - | 1 | 1 | 1 | - | |
| OXA48 | 1 | 1 | - | - | - | - | |
| VIM | - | - | - | 1 | - | - |