NOIDs causative agents: week 13 (week ending 30 March 2025)
Updated 1 April 2025
Laboratories in England have a statutory duty to notify the UK Health Security Agency (UKHSA) of the identification of the following causative agents:
- Bacillus anthracis
- Bacillus cereus
- Bordetella pertussis
- Borrelia spp
- Brucella spp
- Burkholderia mallei
- Burkholderia pseudomallei
- Campylobacter spp
- Carbapenemase-producing Gram-negative bacteria
- Chikungunya virus
- Chlamydophila psittaci
- Clostridium botulinum
- Clostridium perfringens
- Clostridium tetani
- Corynebacterium diphtheriae
- Corynebacterium ulcerans
- Coxiella burnetii
- Crimean-Congo haemorrhagic fever virus
- Cryptosporidium spp
- Dengue virus
- Ebola virus
- Entamoeba histolytica
- Escherichia coli O 157
- Francisella tularensis
- Giardia spp
- Guanarito virus
- Haemophilus influenzae (invasive)
- Hanta virus
- hepatitis A
- hepatitis B
- hepatitis C
- hepatitis D
- hepatitis E
- influenza virus
- Junin virus
- Kyasanur Forest disease virus
- Lassa virus
- Legionella spp
- Leptospira interrogans
- Listeria monocytogenes
- Machupo virus
- Marburg virus
- measles virus
- mpox virus
- mumps virus
- Mycobacterium tuberculosis complex
- Neisseria meningitidis
- Omsk haemorrhagic fever virus
- Plasmodium falciparum
- Plasmodium Knowlesi
- Plasmodium Malariae
- Plasmodium Ovale
- Plasmodium Vivax
- polio virus
- Rabies virus
- Rickettsia spp
- Rift Valley fever virus
- Rubella virus
- Sabia virus
- Salmonella spp
- SARS coronavirus
- Shigella spp
- Streptococcus group A (invasive)
- Streptococcus pneumoniae (invasive)
- Varicella zoster virus
- Variola virus
- Vibrio cholerae
- West Nile virus
- Yellow fever virus
- Yersinia pestis
Statutory Notifications of causative agents, grouped by root organism
Totals for the current week compared to the previous 5.
Week notification received | 2025/08 | 2025/09 | 2025/10 | 2025/11 | 2025/12 | 2025/13 |
---|---|---|---|---|---|---|
Arboviruses | ||||||
West Nile Virus | 1 | 1 | - | - | - | - |
Bacillus | ||||||
Bacillus cereus | 18 | 14 | 16 | 15 | 19 | 12 |
Bordetella | ||||||
Bordetella pertussis | 12 | 7 | 9 | 13 | 4 | 9 |
Borrelia | ||||||
Borrelia burgdorferi | 28 | 19 | 11 | 18 | 19 | 20 |
Borrelia sp | 3 | 7 | 3 | 3 | 2 | 3 |
Brucella | ||||||
Brucella sp | - | 4 | - | 4 | 1 | - |
Campylobacter | ||||||
Campylobacter coli | 32 | 23 | 29 | 33 | 33 | 33 |
Campylobacter fetus | - | 1 | - | - | - | - |
Campylobacter jejuni | 303 | 297 | 307 | 310 | 284 | 220 |
Campylobacter other named | 2 | 3 | 2 | 2 | - | 2 |
Campylobacter rectus | - | 1 | - | - | - | - |
Campylobacter sp | 933 | 1,032 | 1,034 | 1,110 | 1,010 | 965 |
Campylobacter upsaliensis | 1 | 4 | - | 3 | 1 | - |
Campylobacter ureolyticus (bacteroides corrodens) | - | - | - | - | 1 | 3 |
Chikungunya virus | ||||||
Chikungunya virus | 1 | 2 | 1 | 1 | 1 | 1 |
Clostridium | ||||||
Clostridium perfringens | 42 | 31 | 24 | 37 | 40 | 33 |
Coronavirus | ||||||
Coronavirus | 236 | 238 | 189 | 170 | 150 | 127 |
Human coronavirus 229e | - | 1 | 1 | - | - | 1 |
Human coronavirus hku1 | 2 | 1 | 5 | 1 | - | - |
Human coronavirus oc43 | - | - | - | - | 1 | - |
SARS-CoV-2 antibody indeterminate | 2 | - | 2 | 6 | - | - |
SARS-CoV-2 antibody void | 12 | 14 | 26 | 34 | 34 | 34 |
SARS-CoV-2 coronavirus (COVID-19) | 939 | 912 | 920 | 894 | 1,070 | 1,123 |
SARS-CoV-2 coronavirus (COVID-19) indeterminate | 51 | 41 | 55 | 42 | 60 | 35 |
SARS-CoV-2 IgG antibody negative | 27 | 11 | 41 | 18 | 5 | 19 |
SARS-CoV-2 IgG antibody positive | 83 | 32 | 103 | 85 | 47 | 68 |
SARS-CoV-2 total antibody negative | 12 | 8 | 4 | 12 | - | 16 |
SARS-CoV-2 total antibody positive | 13 | 8 | 8 | 41 | 29 | 38 |
Corynebacterium | ||||||
Corynebacterium diphtheriae | 3 | 3 | - | 4 | 5 | 1 |
Corynebacterium ulcerans | - | 1 | - | - | - | 1 |
Coxiella | ||||||
Coxiella burnetii | - | - | 1 | - | - | - |
Cryptosporidium | ||||||
Cryptosporidium hominis | 4 | 4 | 2 | 2 | 6 | 1 |
Cryptosporidium meleagridis | - | - | - | - | - | 1 |
Cryptosporidium parvum | 17 | 17 | 11 | 13 | 28 | 22 |
Cryptosporidium sp | 17 | 28 | 39 | 39 | 24 | 35 |
Cryptosporidium ubiquitum | 1 | - | 2 | - | - | - |
Entamoeba | ||||||
Entamoeba histolytica | 3 | 2 | 6 | 2 | 1 | 3 |
Escherichia | ||||||
Escherichia coli O 157 | 6 | 7 | 10 | 10 | 11 | 6 |
Flaviviruses | ||||||
Dengue virus | 5 | 5 | 1 | 2 | - | 6 |
Giardia | ||||||
Giardia sp | 106 | 95 | 122 | 123 | 106 | 105 |
Haemophilus | ||||||
Haemophilus influenzae | 76 | 79 | 84 | 91 | 76 | 79 |
Hepatitis viruses | ||||||
Hepatitis A | 18 | 18 | 18 | 12 | 13 | 13 |
Hepatitis B | 298 | 279 | 288 | 304 | 309 | 255 |
Hepatitis C | 287 | 214 | 277 | 292 | 289 | 273 |
Hepatitis D | 9 | 3 | 9 | 8 | 6 | 5 |
Hepatitis E | 34 | 45 | 39 | 59 | 27 | 33 |
Influenza virus | ||||||
Influenza A | 2,217 | 1,809 | 1,657 | 1,351 | 1,309 | 1,179 |
Influenza B | 2,197 | 2,045 | 1,649 | 1,435 | 1,235 | 1,156 |
Influenza indeterminate | 1 | - | 1 | - | - | - |
Influenza ungrouped | 75 | 75 | 59 | 40 | 51 | 50 |
Legionella | ||||||
Legionella pneumophila | 1 | 6 | 11 | 6 | 5 | 9 |
Legionella sp | - | 1 | 6 | 2 | 4 | 5 |
Leptospira | ||||||
Leptospira interrogans | - | - | - | 1 | - | 1 |
Listeria | ||||||
Listeria monocytogenes | 5 | 2 | 7 | 3 | 5 | 1 |
Mycobacterium | ||||||
Mycobacterium tuberculosis | 84 | 98 | 93 | 96 | 82 | 72 |
Neisseria | ||||||
Neisseria meningitidis | 33 | 29 | 17 | 33 | 40 | 32 |
Orthopoxvirus | ||||||
Mpox virus positive | 4 | 4 | 4 | 3 | 8 | 7 |
Paramyxoviruses | ||||||
Measles virus | 15 | 20 | 16 | 10 | 9 | 14 |
Mumps virus | 12 | 9 | 7 | 13 | 12 | 9 |
Plasmodium | ||||||
Plasmodium falciparum | - | 1 | 1 | 7 | 12 | - |
Plasmodium malariae | - | - | - | 1 | - | - |
Plasmodium ovale | - | - | - | 1 | 2 | - |
Plasmodium vivax | - | - | - | - | 1 | - |
Polyomavirus | ||||||
Polyomavirus BK | 43 | 60 | 60 | 69 | 46 | 61 |
Polyomavirus JC | 9 | 6 | 9 | 7 | 9 | 14 |
Polyomavirus untyped | 17 | 11 | 14 | 20 | 3 | 11 |
Rickettsia | ||||||
Rickettsia tsutsugamushi | 2 | - | - | - | - | - |
Rubella virus | ||||||
Rubella virus | 2 | 3 | 1 | 1 | 3 | 3 |
Salmonella | ||||||
Other salmonellas | 46 | 50 | 55 | 56 | 39 | 12 |
Salmonella enteritidis | 17 | 26 | 36 | 35 | 7 | 8 |
Salmonella java | 7 | - | - | - | - | - |
Salmonella kentucky | - | - | - | 5 | - | - |
Salmonella newport | - | - | 8 | - | - | - |
Salmonella saint-paul | - | 14 | 6 | 8 | - | - |
Salmonella sp | 10 | 24 | 39 | 38 | 69 | 111 |
Salmonella typhi and paratyphi | 13 | 15 | 5 | 9 | 13 | 11 |
Salmonella typhimurium | 13 | 28 | 13 | 19 | 6 | - |
Shigella | ||||||
Shigella boydii | - | 1 | - | 1 | - | - |
Shigella dysenteriae | - | - | - | - | 1 | 1 |
Shigella flexneri | 14 | 20 | 16 | 17 | 10 | 9 |
Shigella sonnei | 16 | 13 | 12 | 10 | 18 | 13 |
Shigella sp | 33 | 55 | 61 | 72 | 51 | 74 |
Streptococcus | ||||||
Streptococcus group A | 73 | 61 | 52 | 60 | 54 | 74 |
Streptococcus pneumoniae | 152 | 181 | 142 | 131 | 147 | 148 |
Vibrio | ||||||
Vibrio cholerae | 2 | - | 1 | 2 | 1 | 1 |
Carbapenemase-producing Enterobacterales (CPE)
For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.
Note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
Week notification received | 2025/08 | 2025/09 | 2025/10 | 2025/11 | 2025/12 | 2025/13 | |
---|---|---|---|---|---|---|---|
Citrobacter | |||||||
Citrobacter spp | IMP | - | - | 1 | 1 | - | - |
KPC | 1 | 3 | - | 1 | 2 | - | |
NDM | 2 | 2 | - | - | 1 | - | |
OXA48 | - | 4 | 2 | 2 | 2 | - | |
VIM | - | 2 | - | - | - | - | |
Other | 1 | 1 | - | 1 | - | - | |
Enterobacter | |||||||
Enterobacter cloacae complex | IMP | 4 | 4 | 1 | 1 | 1 | - |
KPC | - | 2 | 2 | - | 1 | - | |
NDM | 2 | 5 | 10 | 4 | 8 | 3 | |
OXA48 | 2 | 5 | - | 2 | 2 | - | |
Other | 1 | 2 | - | 1 | - | - | |
Other enterobacter spp | KPC | - | 1 | - | - | - | - |
NDM | - | - | - | - | 1 | - | |
OXA48 | - | - | - | - | 2 | - | |
Escherichia | |||||||
Escherichia coli | KPC | 1 | 3 | 1 | 2 | 1 | - |
NDM | 15 | 16 | 18 | 16 | 17 | 2 | |
OXA48 | 20 | 20 | 25 | 17 | 14 | 4 | |
Other | 2 | 1 | - | 1 | 3 | - | |
Klebsiella | |||||||
Klebsiella aerogenes | KPC | - | - | - | - | 1 | - |
OXA48 | - | 1 | - | - | - | - | |
Klebsiella oxytoca | IMP | - | - | 1 | - | - | - |
KPC | - | - | 1 | 1 | - | - | |
NDM | 2 | - | 1 | 1 | - | - | |
OXA48 | 1 | - | 1 | 1 | - | - | |
Klebsiella pneumoniae | IMP | 1 | - | 2 | - | - | - |
KPC | 7 | 15 | 7 | 5 | 10 | - | |
NDM | 8 | 8 | 7 | 12 | 9 | 2 | |
OXA48 | 13 | 9 | 12 | 11 | 5 | - | |
Other | 1 | 3 | - | 2 | 3 | 1 | |
Klebsiella variicola | OXA48 | 1 | - | - | - | - | - |
Other klebsiella spp | NDM | - | - | - | 1 | - | - |
Other | - | - | - | 1 | - | - | |
Morganella | |||||||
Morganella morganii | NDM | - | 1 | 1 | 1 | - | - |
OXA48 | - | - | 1 | - | - | - | |
Pantoea | |||||||
Pantoea spp | Other | 1 | - | - | - | - | - |
Proteus | |||||||
Proteus mirabilis | NDM | 2 | 2 | 3 | 1 | 1 | - |
OXA48 | 1 | - | - | - | 1 | - | |
Other | 1 | 1 | 2 | 1 | 1 | - | |
Providencia | |||||||
Providencia stuartii | Other | - | - | - | - | - | 1 |
Raoultella | |||||||
Raoultella ornithinolytica | KPC | - | - | 1 | - | - | - |
OXA48 | - | 1 | - | - | - | - | |
Serratia | |||||||
Serratia marcescens/ureilytica | NDM | - | - | 1 | - | - | - |
OXA48 | - | 1 | - | - | - | - |
Other carbapenemase-producing Gram-negative organisms
For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.
Note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
Week notification received | 2025/08 | 2025/09 | 2025/10 | 2025/11 | 2025/12 | 2025/13 | |
---|---|---|---|---|---|---|---|
Acinetobacter | |||||||
Acinetobacter baumannii | NDM | 2 | 1 | 3 | 1 | 2 | - |
Other acinetobacter spp | NDM | 1 | - | - | - | - | - |
Pseudomonas | |||||||
Pseudomonas aeruginosa | IMP | 1 | - | - | - | - | - |
NDM | 2 | 1 | 2 | 1 | - | - | |
Other | 2 | 2 | 1 | 1 | 1 | - | |
Pseudomonas stutzeri group | NDM | 1 | - | - | - | - | - |
Other pseudomonas spp | NDM | - | 1 | 1 | - | - | - |
VIM | - | 1 | - | - | - | - | |
Other | - | 1 | 1 | - | - | - | |
Other | |||||||
KPC | - | 1 | - | - | 1 | - | |
NDM | 1 | - | - | - | - | - | |
OXA48 | 1 | - | - | - | - | - |