Research and analysis

Poly Implant Prosthèse (PIP) implants: toxicology testing

Details of the toxicology testing carried out on PIP breast implants by the Medicines and Healthcare products Regualtory Agency (MHRA) between 2010 and 2012.

Documents

Analysis of organic extracts

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Results of the UK PIP testing

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The Ames test: reverse mutation in 5 histidine-requiring strains of Salmonella typhimurium

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Evaluation of in vitro cytotoxicity on balb/c 3T3 fibroblasts using the neutral red uptake assay

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An assessment of in vitro skin irritation using EpiSkin™

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Chemical analysis: comparative analysis of silicone implant samples

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Chemical analysis summary

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Determination of total silicon in milk

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Silicon in breast milk summary

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Details

This document sets out the results of the toxicology tests carried out by MHRA on PIP breast implants after it issued advice in 2010 to clinicians to no longer implant them.

Updates to this page

Published 18 December 2014

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