Poly Implant Prosthèse (PIP) implants: toxicology testing
Details of the toxicology testing carried out on PIP breast implants by the Medicines and Healthcare products Regualtory Agency (MHRA) between 2010 and 2012.
- From:
- Medicines and Healthcare products Regulatory Agency
- Published
- 18 December 2014
Documents
Analysis of organic extracts
PDF, 4.21 MB, 51 pages
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Results of the UK PIP testing
PDF, 25.8 KB, 2 pages
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The Ames test: reverse mutation in 5 histidine-requiring strains of Salmonella typhimurium
PDF, 48.8 MB, 274 pages
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Evaluation of in vitro cytotoxicity on balb/c 3T3 fibroblasts using the neutral red uptake assay
PDF, 7.41 MB, 39 pages
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An assessment of in vitro skin irritation using EpiSkin™
PDF, 4.16 MB, 18 pages
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Chemical analysis: comparative analysis of silicone implant samples
PDF, 8.72 MB, 42 pages
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Chemical analysis summary
PDF, 171 KB, 6 pages
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Determination of total silicon in milk
PDF, 2.18 MB, 6 pages
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Silicon in breast milk summary
PDF, 140 KB, 1 page
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Details
This document sets out the results of the toxicology tests carried out by MHRA on PIP breast implants after it issued advice in 2010 to clinicians to no longer implant them.