SaBTO virology subcommittee recommendations on KSHV infection
Recommendations to introduce universal serological screening of deceased donors for Kaposi's sarcoma-associated herpesvirus (KSHV) infection.
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Several cases of fatal Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus type-8 (HHV-8), infection have been observed in recent years in recipients of solid organ transplants in the UK.
The Advisory Committee on the Safety of Blood, Tissues and Organs (SaBTO) established a workstream to look at the current scientific evidence and assess the size and impact of donor related HHV-8 infection on recipient outcomes, particularly in the setting of deceased organ donation. The working group also assessed the need and feasibility of implementing appropriate interventions.