Guidance

SARS-CoV-2 variants of public health interest: 12 November 2021

Updated 21 April 2023

Position as of 8 November 2021.

Horizon scan

International epidemiology scan 5 November 2021
Imported sample mutation scan 4 November 2021
Signals in monitoring scan 4 November 2021
Phylogenetic cluster detection 2 November
International mutation scan 2 November
Domestic mutation scan 5 November
Reinfections scan 5 November
Vaccinees scan 22 October 2021
Signals investigated 12 October to 25 October 2021 10
New genomes 12 October to 25 October 2021 100,623

Note: Signals of individual mutations and new clusters are excluded until defined variant is identified.

SARS-CoV-2 variants of public health interest: variants detected in the UK

Variants of concern

Alpha (VOC-20DEC-01, B.1.1.7)
Beta (VOC-20DEC-02, B.1.351)
Gamma (VOC-21JAN-02, P.1)
Delta (VOC-21APR-02, and all sub-lineages, unless named elsewhere on the grid)

Variants under investigation

Kappa (VUI-21APR-01, B.1.617.1)
Mu (VUI-21JUL-01, B.1.621)
VUI-21OCT-01 (AY.4.2)
Eta VUI-21FEB-03 (B.1.525)

Signals currently under monitoring and investigation

B.1.427/B.1.429
B.1.620
C.1.2
R.1
C.36.3
B.1.640
Delta + E484K Phylogenetic Cluster

SARS-CoV-2 variants of public health interest: variants present in GISAID but not detected in the UK

International variants of concern

N/A

International variants under investigation

Zeta (VUI-21JAN-01, P.2)
Theta (VUI-21MAR-02, P.3)
VUI-21FEB-04 (B.1.1.318)
VUI-21APR-03 (B.1.617.3)
VUI-21MAY-01 (AV.1)
Lambda (VUI-21JUN-01, C.37)

International signals under monitoring

Alpha with Q677H
B.1 with 214insQAS
AT.1
B.1.629
B.1.619
B.1.631, B.1.630, B.1.628
P.1.8
P.5
B.1.1.7 and B.1.617.2
C.37 (S:L5F, G75V, D614G, L452Q, E484K, P499R, N501T, H655Y, P681R, T859N)
A.27
Iota (B.1.526)

SARS-CoV-2 variants of public health interest: variants that have become provisionally extinct

Variants provisionally extinct (not detected for 12 weeks in the UK or in GISAID)

VUI-21FEB-01 (A.23.1 with E484K)
VOC-21FEB-02 (Alpha with E484K)
VUI-21MAR-01 (B.1.324.1 with E484K)

Signals provisionally extinct (not detected for 12 weeks in the UK or in GISAID)

A.30
B.1.633
B.1.214.2
Alpha with S494P