Guidance

SARS-CoV-2 variants of public health interest: 20 May 2022

Updated 21 April 2023

Position as of 16 May 2022.

Horizon scan

International epidemiology scan 16 May 2022
Lineage and signals growth rates scan 16 May 2022
Phylogenetic cluster detection 16 May 2022
International mutation scan 16 May 2022
Domestic mutation scan 16 May 2022
Signals investigated from 4 May to 16 May 2022 5
New genomes 4 May to 16 May 2022 22,963

Note: signals of individual mutations and new clusters are excluded until defined variant is identified.

SARS-CoV-2 variants of public health interest: variants detected in the UK

UKHSA-designated variants of concern

Omicron (VOC-21NOV-01/B.1.1.529/BA.1 and all sub-lineages, unless separately designated by UKHSA)
Omicron (VOC-22JAN-01/B.1.1.529/BA.2 and all sub-lineages, unless separately designated by UKHSA)
Omicron (B.1.1.529) sub-lineage BA.5 (VOC-22APR-04)
Omicron (B.1.1.529) sub-lineage BA.4 (VOC-22APR-03)

UKHSA-designated variants

XE recombinant (V-22APR-02/BA.1 x BA.2)
Delta (V-21APR-02 and all sub-lineages, unless named elsewhere on the grid)
Alpha (V-20DEC-01/B.1.1.7)
V-21OCT-01 (AY.4.2)

Signals currently under monitoring and investigation

BA.3
Delta and Omicron recombinant lineages (UK)
XF recombinant
BA.1/BA.2 recombinant (with unique mutation C3583T)
BA.2.12.1

SARS-CoV-2 variants of public health interest: variants present in GISAID but not detected in the UK

International variants of concern

Beta (V-20DEC-02, B.1.351)

International variants

XD Recombinant (V-22APR-01, Delta x BA.1)
B.1.525 (previously VUI-21FEB-03)

International signals under monitoring

AY.119.2/BA.1.1 Recombinant

SARS-CoV-2 variants of public health interest: variants which have become provisionally extinct

Variants provisionally extinct (not detected for 12 weeks in the UK or in GISAID)

P.1 (Gamma) (previously VOC-21JAN-02)
A.23.1 with E484K (previously VUI-21FEB-01)
Alpha with E484K (previously VOC-21FEB-02)
B.1.324.1 with E484K (previously VUI-21MAR-01)
AV.1 (previously VUI-21MAY-01)
P.3 (previously VUI-21MAR-02)
B.1.318 (previously VUI-21FEB-04)
P.2 (previously VUI-21JAN-01)
B.1.617.1 (previously VUI-21APR-01)
A.27
C.36.3
Iota (B.1.526)
Mu (V-21JUL-01, B.1.621)
V-21APR-03 (B.1.617.3)

Signals provisionally extinct (not detected for 12 weeks in the UK or in GISAID)

A.30
B.1.633
AT.1
P.5
R.1
B.1.620
B.1.1.7 + B.1.617.2 (XC Recombinant)
B.1.214.2
B.1.619
B.1.640

Signals removed after review

Variants under investigation and signals in monitoring may be removed from the grid if they show consistently low growth rates.

AY.33
AY.34
AY.43
B.1.629
B.1.630
B.1.628 recombinant of (B.1.631 and B.1.634)
C.1.2
C.37 (Lambda) (previously VUI-21JUN-01)
C.37 (2nd Gen)
Epsilon (B.1.427/B.1.429)
P.1.8
Variant associated with North America: USA 214insQAS Samples
Delta + E484K Phylogenetic Cluster