Guidance

SARS-CoV-2 variants of public health interest: 22 July 2022

Updated 21 April 2023

Position as of 18 July 2022.

Horizon scan

International epidemiology scan 19 July 2022
Lineage and signals growth rates scan 19 July 2022
Phylogenetic cluster detection 19 July 2022
International mutation scan 19 July 2022
Domestic mutation scan 19 July 2022
Signals investigated from 21 June 2022 to 18 July 7
New genomes 19 June 2022 to 17 July 2022 56,773

Note: Signals of individual mutations and new clusters are excluded until defined variant is identified.

SARS-CoV-2 variants of public health interest: variants detected in the UK

UKHSA designated variants of concern

Omicron (VOC-21NOV-01/B.1.1.529/BA.1 and all sub-lineages unless separately designated by UKHSA)
Omicron (VOC-22JAN-01/B.1.1.529/BA.2 and all sub-lineages unless separately designated by UKHSA)
Omicron (B.1.1.529) sub-lineage BA.5 (VOC-22APR-04)
Omicron (B.1.1.529) sub-lineage BA.4 (VOC-22APR-03)

UKHSA designated variants

XE recombinant (V-22APR-02/BA.1 x BA.2)
Delta (V-21APR-02, and all sub-lineages, unless named elsewhere on the grid)
V-21OCT-01 (AY.4.2)
V-22JUL-01 (BA.2.75)

Signals currently under monitoring and investigation

Delta and Omicron recombinant lineages (UK)
Unassigned Omicron, potential BA.2 recombinant with chronic infection markers: S: M153I, T299I, R346K, L368I, E484K, ntG1219C
BA.3

SARS-CoV-2 variants of public health interest: variants present in GISAID but not detected in the UK

International variants

Alpha (V-20DEC-01/B.1.1.7)

SARS-CoV-2 variants of public health interest: variants which have become provisionally extinct

Variants provisionally extinct (not detected for 12 weeks in the UK or in GISAID)

P.1 (Gamma) (previously VOC-21JAN-02)
A.23.1 with E484K (previously VUI-21FEB-01)
Alpha with E484K (previously VOC-21FEB-02)
B.1.324.1 with E484K (previously VUI-21MAR-01)
AV.1 (previously VUI-21MAY-01)
P.3 (previously VUI-21MAR-02)
B.1.318 (previously VUI-21FEB-04)
P.2 (previously VUI-21JAN-01)
B.1.617.1 (previously VUI-21APR-01)
A.27
C.36.3
Iota (B.1.526)
Mu (V-21JUL-01, B.1.621)
V-21APR-03 (B.1.617.3)
Beta (VOC-20DEC-02, B.1.351)
B.1.525 (previously VUI-21FEB-03)
XD recombinant (V-22APR-01, Delta x BA.1)

Signals provisionally extinct (not detected for 12 weeks in the UK or in GISAID)

A.30
B.1.633
AT.1
P.5
R.1
B.1.620
B.1.1.7 + B.1.617.2 (XC recombinant)
B.1.214.2
B.1.619
B.1.640
AY.119.2/BA.1.1 recombinant
XF recombinant

Signals removed after review

VUIs and signals in monitoring may be removed from the grid if they show consistently low growth rates.

AY.33
AY.34
AY.43
B.1.629
B.1.630
B.1.628 recombinant of (B.1.631 and B.1.634)
C.1.2
C.37 (Lambda) (previously VUI-21JUN-01)
C.37 (2nd Gen)
Epsilon (B.1.427/B.1.429)
P.1.8
Variant associated with North America: USA 214insQAS samples
Delta + E484K phylogenetic cluster