SARS-CoV-2 variants of public health interest: 25 November 2022
Updated 21 April 2023
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Position as of 21 November 2022.
Horizon scan
| Lineage and signals growth rates scan | 21 November 2022 |
| International mutation scan | 21 November 2022 |
| Domestic mutation scan | 21 November 2022 |
| Signals investigated from 26 October 2022 to 21 November 2022 | 6 |
| New genomes 26 October 2022 to 21 November 2022 | 20,840 |
Note: Signals of individual mutations and new clusters are excluded until defined variant is identified.
SARS-CoV-2 variants of public health interest: variants detected in the UK
UKHSA designated variants of concern
| Omicron (VOC-21NOV-01/B.1.1.529/BA.1, and all sub-lineages unless separately designated by UKHSA) |
| Omicron (VOC-22JAN-01/B.1.1.529/BA.2 and all sub-lineages unless separately designated by UKHSA) |
| Omicron (B.1.1.529) sub-lineage BA.5 (VOC-22APR-04) |
| Omicron (B.1.1.529) sub-lineage BA.4 (VOC-22APR-03) |
UKHSA designated variants
| Omicron BA.2.12.1 (V-22MAY-01) |
| Delta (B.1.617.2 and sublineages, V-21APR-02) |
| Omicron BA.2.75 (V-22JUL-01) |
| Omicron BA.4.6 (V-22SEP-01) |
| Omicron BQ.1 (V-22OCT-01) |
| Omicron XBB recombinant (V-22OCT-02) |
Signals currently under monitoring and investigation
| Delta and Omicron recombinant XBC |
| BA.2.75.2 |
| BQ.1.1 |
| BN.1 (BA.2.75.5.1.) |
| BA.5.2.35 |
SARS-CoV-2 variants of public health interest: variants present in GISAID but not detected in the UK
International signals under monitoring
| Cluster of BA.5.7 samples with high number of additional mutations |
SARS-CoV-2 variants of public health interest: variants which have become provisionally extinct
Variants provisionally extinct (not detected for 12 weeks in the UK or in GISAID)
| Alpha (V-20DEC-01/B.1.1.7) |
| P.1 (Gamma) (previously VOC-21JAN-02) |
| A.23.1 with E484K (previously VUI-21FEB-01) |
| Alpha with E484K (previously VOC-21FEB-02) |
| B.1.324.1 with E484K (previously VUI-21MAR-01) |
| AV.1 (previously VUI-21MAY-01) |
| P.3 (previously VUI-21MAR-02) |
| B.1.318 (previously VUI-21FEB-04) |
| P.2 (previously VUI-21JAN-01) |
| B.1.617.1 (previously VUI-21APR-01) |
| A.27 |
| C.36.3 |
| Iota (B.1.526) |
| Mu (V-21JUL-01, B.1.621) |
| Beta (VOC-20DEC-02, B.1.351) |
| B.1.525 (previously VUI-21FEB-03) |
| XD recombinant (V-22APR-01, Delta x BA.1) |
| V-21OCT-01 (AY.4.2) |
| V-21APR-03 (B.1.617.3) |
Signals provisionally extinct (not detected for 12 weeks in the UK or in GISAID)
| A.30 |
| B.1.633 |
| AT.1 |
| P.5 |
| R.1 |
| B.1.620 |
| B.1.1.7 + B.1.617.2 (XC recombinant) |
| B.1.214.2 |
| B.1.619 |
| B.1.640 |
| AY.119.2/BA.1.1 recombinant |
| XF recombinant |
Signals removed after review
Variants under investigation (VUIs) and signals in monitoring may be removed from the grid if they show consistently low growth rates.
| AY.33 |
| AY.34 |
| AY.43 |
| B.1.629 |
| B.1.630 |
| B.1.628 recombinant of (B.1.631 and B.1.634) |
| C.1.2 |
| C.37 (Lambda) (Previously VUI-21JUN-01) |
| C.37 (2nd Gen) |
| Epsilon (B.1.427/B.1.429) |
| P.1.8 |
| Variant Associated with North America: USA 214insQAS Samples |
| Delta + E484K phylogenetic cluster |
| Unassigned Omicron, potential BA.2 recombinant |
| BJ.1 |
| BA.3 |
| BA.4.7 |
| BF.7 (BA.5.2.1) |
| BS.1 (BA.2.3.2.1) |
| Omicron and Delta recombinant XAW |
| BA.2.3.20 |