Anamnestic responses in pigs to the Taenia solium TSOL18 vaccine and implications for control strategies
Specific antibody responses were assessed in pigs immunised with the Taenia solium vaccine TSOL18
Abstract
Specific antibody responses were assessed in pigs immunized with the Taenia solium vaccine TSOL18. Anti-TSOL18 responses were compared 2 weeks after secondary immunization, where the interval between primary and secondary immunization was 4, 8, 12, 16 or 20 weeks. All animals responded to the vaccine and there was no diminution in antibody responses in animals receiving their second injection after an interval up to 20 weeks. Pigs receiving vaccinations at an interval of 12 weeks developed significantly increased antibody responses compared with animals receiving immunizations 4 weeks apart (P = 0·046). The ability to deliver TSOL18 vaccination effectively where the revaccination schedule can be delayed for up to 12-16 weeks in pigs increases the options available for designing T. solium control interventions that incorporate TSOL18 vaccination.
This is an output from the ‘Global Alliance For Livestock Veterinary Medicines (GALVmed): Phase 2 – Protecting Livestock and Saving Human Lives’ programme
Citation
Lightowlers MW, Donadeu M, Elaiyaraja M, Maithal K, Kumar KA, Gauci CG, Firestone SM, Sarasola P, Rowan TG. (2016) Anamnestic responses in pigs to the Taenia solium TSOL18 vaccine and implications for control strategies. Parasitology; 143(4):416-20 https://doi.org/10.1017/S0031182016000202