Assessing anti-T. cruzi candidates in vitro for sterile cidality
This research is an output from the Drugs for Neglected Diseases (DNDi) initiative
Abstract
It seems to be important for new drug candidates for Chagas disease to totally clear the T. cruzi infection (sterile cure), thus ensuring long-term beneficial effects for patients in the chronic indeterminate stage avoiding relapse. The authors have adapted an in vitro system to predict the ability of a compound to deliver sterile cure.
This research was primarily funded by the Drugs for Neglected Diseases (DNDi) initiative.
Citation
Cal M, Ioset JR, Fügi M, Mäsera P, Kaiser M. (2016). Assessing anti-T. cruzi candidates in vitro for sterile cidality. International Journal for Parasitology: Drugs and Drug Resistance Volume 6, Issue 3, December 2016, Pages 165-170 https://doi.org/10.1016/j.ijpddr.2016.08.003
Links
Assessing anti-T. cruzi candidates in vitro for sterile cidality