Cassava HapMap: Masking deleterious mutations in a clonal crop species

Cassava is an important staple food crop, however, ubiquitous deleterious mutations may severely reduce its fitness

• From: Department for International Development
• Published: 23 December 2016

• Document Type: Journal Article
• Theme: Agriculture
• Authors: Ramu, P, Esuma, W, Kawuki, R, Rabbi, I.Y.

Abstract

Cassava is an important staple food crop in Africa and South America, however, ubiquitous deleterious mutations may severely reduce its fitness. To evaluate these deleterious mutations in the cassava genome, we constructed a cassava haplotype map using deep sequencing from 241 diverse accessions and identified over 28 million segregating variants.

This work is part of the “Next Generation Cassava Breeding Project” which is supported by the UK Department for International Development, in partnership with the Bill & Melinda Gates Foundation.

Citation

Punna Ramu, Williams Esuma, Robert Kawuki, Ismail Y Rabbi, Chiedozie Egesi, Jessen V Bredeson. Cassava HapMap: Masking deleterious mutations in a clonal crop species bioRxiv 23 December 2016 https://doi.org/10.1101/077123

Links

Cassava HapMap: Masking deleterious mutations in a clonal crop species

Published 23 December 2016