Chagas disease research and development: is there light at the end of the tunnel?

Chagas disease is endemic in Latin America and spreading around the globe due to human migration

Abstract

Although Chagas disease was first identified more than a century ago, many questions about the disease remain. In fact, the current status of evidence and available data do not allow any absolute statement related to treatment needs and outcome for Chagas patients to be made.  Although there has been some new impetus in Research and Development for Chagas disease following recent clinical trials, there is a need to review and challenge the current status of evidence and define basic and clinical research priorities and next steps in the field. This should ensure that the best drugs for Chagas disease are developed, but will require a focused and collaborative effort of the entire Chagas disease research community.

This research is part of the Drugs for Neglected Diseases initiative (DNDi).

Citation

Chatelain, E. Chagas disease research and development: is there light at the end of the tunnel? (2016) Computational and Structural Biotechnology Journal 2016;15:98-103. doi: 10.1016/j.csbj.2016.12.002

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Published 16 December 2016