Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities

Interferons are essential components of the host innate immune system and define first-line of defence against pathogens

From:
Department for International Development
Published
2 June 2017
Country:
Pakistan, Vietnam
Document Type:
Journal Article
Theme:
Agriculture
Authors:
Santhakumar, D, Iqbal, M, Nair, V, Munir, M

Abstract

Interferons (IFNs) are essential components of the host innate immune system and define first-line of defence against pathogens. In mammals, several type I IFNs are identified, however, only limited data is available on the repertoire of IFNs in avian species. Here we report the characterization of chicken IFN-κ (chIFN-κ) near the type I IFN locus on the sex-determining Z chromosome.

This work arises from the Zoonoses and Emerging Livestock Systems (ZELS) programme.

Citation

Santhakumar D, Iqbal M, Nair V, Munir M. (2017). Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities. Sci Rep. 7(1): 2719

Chicken IFN Kappa: A Novel Cytokine with Antiviral Activities

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Published 2 June 2017
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