Development of a scalable process for the synthesis of DNDI-VL-2098: A potential preclinical drug candidate for the treatment of VL
A study on the treatment of visceral leishmaniasis
Abstract
This study describes the elaboration of a process suitable for the kilogram scale synthesis of DNDI-VL-2098, a preclinical candidate for the treatment of visceral leishmaniasis.
This research was funded by the Drugs for Neglected Diseases initiative (DNDi) programme
Citation
Vijay S. Satam, Rao Pedada S, Kamaraj P, Antao N, Singh A, Hindupur RM, Pati HN, Thompson AM, Launay D, Martin D.(2016) Development of a scalable process for the synthesis of DNDI-VL-2098: A potential preclinical drug candidate for the treatment of VL. Org. Process Res. Dev., 2017, 21 (1), pp 52–59 DOI: 10.1021/acs.oprd.6b00331