Effect of ghrelin on mortality and cardiovascular outcomes in experimental rat and mice models of heart failure
This is a systematic review and meta-analysis
Abstract
Heart failure continues to be a challenging condition in terms of prevention and management of the disease. Studies have demonstrated various cardio-protective effects of Ghrelin. The aim of the study is to determine the effect of Ghrelin on mortality and cardiac function in experimental rats/mice models of heart failure
This research is supported by the Department for International Development’s Evidence Building and Synthesis Research Programme which is led by Liverpool School of Tropical Medicine
Citation
Mahalaqua Nazli Khatib, Anuraj Shankar, Richard Kirubakaran, Kingsley Agho, Padam Simkhada, Shilpa Gaidhane, Deepak Saxena, Unnikrishnan B, Dilip Gode, Abhay Gaidhane, Syed Quazi Zahiruddin. Effect of Ghrelin on Mortality and Cardiovascular Outcomes in Experimental Rat and Mice Models of Heart Failure: A Systematic Review and Meta-Analysis : Public Library of Science (PLOS) One 2015; 10(5): e0126697. doi: 10.1371/journal.pone.0126697