In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses

Journal article in Reproductive Toxicology

• From: Department for International Development
• Published: 1 June 2014

• Document Type: Journal Article
• Theme: Health
• Authors: Longo, M, Zanoncelli, S, Messina, M, Scandale, I, Mackenzie, C, Geary, T, Marsh, K, Lindley, D, Mazue, G

Abstract

Flubendazole, in a new formulation with high systemic bioavailability, has been proposed as a macrofilaricide against filarial diseases. The embryotoxic activity of a new oral flubendazole formulation was investigated. It did not interfere with rat embryofetal development.

This research is part of the Drugs for Neglected Diseases initiative (DNDi)

Citation

Longo M, Zanoncelli S, Messina M, Scandale I, Mackenzie C, Geary T, Marsh K, Lindley D, Mazué G.(2014) In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses. Reproductive Toxicology Volume 49, November 2014, Pages 33-42 https://doi.org/10.1016/j.reprotox.2014.06.009

Links

In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses

Published 1 June 2014