Management of chronic Hepatitis C at a primary health clinic in the high-burden context of Karachi, Pakistan

Analysis of an interferon-free, decentralised programme in the community clinic in Machar Colony

Abstract

The burden of hepatitis C (HCV) infection in Pakistan is among the highest in the world, with a reported national HCV prevalence of 6.7% in 2014. In specific populations, such as in urban communities in Karachi, the prevalence is suspected to be higher. Interferon-free treatment for chronic HCV infection (CHC) could allow scale up, simplification and decentralization of treatment to such communities. The authors present an interim analysis over the course of February-December 2015 of an interferon-free, decentralised CHC programme in the community clinic in Machar Colony, Karachi, Pakistan.

This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)

Citation

Capileno YA, Van den Bergh R, Donchunk D, Hinderaker SG, Hamid S, Auat R, Khalid GG, Fatima R, Yaqoob A, Van Overloop C. Management of chronic Hepatitis C at a primary health clinic in the high-burden context of Karachi, Pakistan. PLoS One. 2017;12(4):e0175562.

Management of chronic Hepatitis C at a primary health clinic in the high-burden context of Karachi, Pakistan

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Published 27 April 2017