The "Ebola ça suffit" Vaccine Trial Team. Ring vaccination for Ebola
A novel approach to evaluate vaccine efficacy and effectiveness during an outbreak
Abstract
A World Health Organization expert meeting on Ebola vaccines proposed urgent safety and efficacy studies in response to the outbreak in West Africa. One approach to communicable disease control is ring vaccination of individuals at high risk of infection due to their social or geographical connection to a known case. This paper describes the protocol for a novel cluster randomised controlled trial design which uses ring vaccination.
This research was supported by the Research for Health in Humanitarian Crises (R2HC) Programme
Citation
Henao-Restrepo, Ana Maria. The “Ebola ça suffit” Vaccine Trial Team. Ring vaccination for Ebola : a novel approach to evaluate vaccine efficacy and effectiveness during an outbreak. BMJ 2015;351:h3740