Tuberculosis risk factors and Mycobacterium tuberculosis transmission among HIV-infected patients in Vietnam
Vietnam ranked 16th among high-burden TB countries and 13th among high-burden multi-drug resistant TB countries in 2016
Abstract
Effective tuberculosis (TB) control poses a major public health challenge in Vietnam. Vietnam ranked 16th among high-burden TB countries and 13th among high-burden multi-drug resistant (MDR) TB countries in 2016, with MDR-TB reported in 4.1% of new and 26% of retreatment cases. The emergence of MDR-TB threatens recent progress in TB control, especially in settings where co-infection with human immunodeficiency virus (HIV) complicates the situation even further. Patients with TB/HIV co-infection experience increased mortality if initiation of antiretroviral treatment (ART) is delayed or first-line TB treatment is suboptimal in the absence of drug susceptibility testing (DST)
A recent retrospective study conducted in Ho Chi Minh city, Vietnam, suggested that TB/HIV co-infection is associated with relatively high rates of drug resistance in Mycobacterium tuberculosis.
This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)
Citation
Mai TQ, Martinez E, Menon R, Van Anh NT, Hien NT, Lan NH, Giang DC, Hang PT, Thuong PH, Van Huan H, Hoang NP, Nhung NV, Hoa NB, Marais BJ, Sintchenko V. Tuberculosis risk factors and Mycobacterium tuberculosis transmission among HIV-infected patients in Vietnam. Tuberculosis. 2019;115:67–75.