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Stop prescribing Picato and consider other treatment options for actinic keratosis as appropriate. The licence of ingenol mebutate (Picato) has been suspended as a precautionary measure while the European Medicines Agency (EMA) continues to investigate concerns about a possible increased...
Avoid treatment with febuxostat in patients with pre-existing major cardiovascular disease (for example, myocardial infarction, stroke, or unstable angina), unless no other therapy options are appropriate. Findings from a phase 4 clinical study (the CARES study) in patients with gout...
There have been reports of necrotising and haemorrhagic pancreatitis in people taking exenatide some of which were fatal - stop exenatide treatment if pancreatitis is diagnosed.
Advise patients treated with ingenol mebutate gel to be vigilant for new skin lesions and to seek medical advice immediately should any occur. Use with caution in patients with a history of skin cancer.
The British Consulate has issued advice to British Nationals holidaying on the Atlantic Coast on the dangers of currents known as “baïnes”.
First published during the 2010 to 2015 Conservative and Liberal Democrat coalition government
Collision between a container vessel and a gas carrier in the approaches to Algeciras, Spain.
The British Consulate is running a prevention campaign, giving safety advice to British Nationals on the dangers of “baïnes”.
First published during the 2015 to 2016 Cameron Conservative government
Onivyde has been associated with reports of serious thromboembolic events, such as pulmonary embolism, venous thrombosis, and arterial thromboembolism.
(Hospira) Due to insulation abrasion. (MDA/2013/007)
Manufactured by St Jude Medical – risk of unpredictable, rapid battery depletion leading to potential device failure and loss of therapy.
(All) harm of inadequate patient ventilation and oxygenation could have been avoided if an alternative means of ventilation had been used earlier. (MDA/2010/036)
Letters were sent about ranibizumab and Emerade adrenaline auto-injectors. Alerts were issued about ranitidine, paracetamol, omeprazole, mitomycin-C Kyowa, folic acid, and Emerade adrenaline auto-injectors.
Atypical femoral fractures reported rarely with bisphosphonate therapy, mainly in patients receiving long-term treatment for osteoporosis.
Letters were sent about Myocrisin (sodium aurothiomalate), Cerliponase alfa (Brineura▼), Darzalex▼(daratumumab), retinoids▼, and febuxostat (Adenuric). A recall alert was issued for medicines that were taken out of the regulated medicines supply chain during distribution. Other alerts were issued about paracetamol...
This article focuses on air safety occurrence reporting, and the provision of an improved Air Safety Information Management System (ASIMS).
First published during the 2016 to 2019 May Conservative government
A letter was sent regarding InductOs (solvent and matrix for implantation) to inform of a potential shortage.
OFT closed case: Anticipated acquisition by Koninklijke DSM N.V. of Avecia Holdings B.V.
How UK aid has helped thousands of families return to their homes in Leogane
Businesses will be spared thousands of hours of form-filling each year in a Government move to restore common sense to health and safety.
Twelve people’s lives might have been saved in 2013 if they had been wearing a lifejacket or buoyancy aid.
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