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Medicines, medical devices

Guidance and regulation

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  • Project Orbis is a programme to review and approve promising cancer drugs helping patients access treatments faster.

  • Pharmacy (P), prescription-only (POM), and general sale list (GSL) medicines: apply to move your medicine to a different classification.

  • Who can supply or administer medicines to patients without a doctor under a PGD, which medicines they can supply, and legal requirements for PGDs.

  • These reports explain our assessment of the scientific evidence used to lead to regulatory decisions on the safety of medicines or medicines classes.

  • How the MHRA makes decisions on what is a medicinal product (borderline products).

  • This document provides guidance on the data integrity expectations that should be considered by organisations involved in any aspect of the pharmaceutical lifecycle or GLP studies regulated by MHRA.

  • Safety leaflet on topical corticosteroids and withdrawal reactions to help patients and their carers to use these medicines safely.

  • Detailed guidance on advertising and promoting medicines.

  • Guidance and advice for community pharmacies in England providing services to people who use drugs and alcohol.

  • Fees payable to the MHRA from 2025.

  • Take care when using creams to treat dry skin conditions as they can easily dry onto clothing, bedding and bandages, making them more flammable.

  • The process for applicants applying for a paediatric investigation plan (PIP) modification or waiver.

  • A digital platform designed to facilitate the reporting, monitoring, and management of medical device incidents.

  • How the MHRA makes decisions on whether a borderline product is a medical device and whether medical devices regulations should apply.

  • How the MHRA processes variations to medicines' marketing authorisations for the UK and Northern Ireland.

  • Guidance on out of specification investigations, including definitions and laboratory analysis and phase I,II and III investigations.

  • How to use the procedure for medicines licensing applications.

  • Information on comparator products used in studies supporting abridged marketing authorisation application.

  • Guidance for UK wholesalers and manufacturers on how to import human medicines including unlicensed medicines, how to apply for a licence and how much it costs.

  • Guidance on the deadlines for initial and response submissions.