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Medicines, medical devices

Guidance and regulation

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  • How the MHRA processes variations to medicines' marketing authorisations for the UK and Northern Ireland.

  • Pharmacy (P), prescription-only (POM), and general sale list (GSL) medicines: apply to move your medicine to a different classification.

  • Information on comparator products used in studies supporting abridged marketing authorisation application.

  • Safety leaflet on topical corticosteroids and withdrawal reactions to help patients and their carers to use these medicines safely.

  • How to conform with the legal requirements for placing medical devices on the market.

  • Information on when software applications (apps) are considered to be a medical device and how they are regulated.

  • Who can supply or administer medicines to patients without a doctor under a PGD, which medicines they can supply, and legal requirements for PGDs.

  • How to interpret post-market surveillance (PMS) requirements for medical devices in Great Britain.

  • Provides a standard framework for NHS procurement professionals to assess non-financial value when buying medical technology.

  • The Innovative Licensing and Access Pathway (ILAP) is focused on getting the most transformative new medicines to patients in the UK health system more quickly.

  • Fees payable to the MHRA from 2025.

  • Guidance on the Ionising Radiation (Medical Exposure) Regulations 2017 for employers and health professionals who carry out medical radiological procedures.

  • Information on applying for New Active Substance Work Sharing Initiative (NASWSI) and Biosimilar Work Sharing Initiative (BSWSI) assessments and list of approved products.

  • Guide for marketing authorisation holders, including qualified person responsible for pharmacovigilance (PV) and pharmacovigilance system master files (PSMF).

  • Information about medical devices that the public can buy for personal use and how we make sure they are safe and effective.

  • Consumer advice and details of how to report problems with e-cigarettes with guidance on how to place an e-cigarette on the market in Great Britain and Northern Ireland, including the notification scheme.

  • This document provides guidance on the data integrity expectations that should be considered by organisations involved in any aspect of the pharmaceutical lifecycle or GLP studies regulated by MHRA.

  • How the MHRA makes decisions on whether a borderline product is a medical device and whether medical devices regulations should apply.

  • How the MHRA makes decisions on whether a borderline product is a medical device and which risk class should apply.

  • Detailed guidance on advertising and promoting medicines.