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Medicines, medical devices

Guidance and regulation

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  • Guidance on the Ionising Radiation (Medical Exposure) Regulations 2017 for employers and health professionals who carry out medical radiological procedures.

  • Information on applying quality by design, risk‑based quality management, and proportionate oversight in UK clinical trials.

  • How to register on the MHRA portal and use it to apply for and update marketing authorisations and make other applications.

  • Guidance on the MHRA’s national assessment procedure for marketing authorisation applications.

  • Webinar recordings providing information about plans for implementing the new Clinical Trial Regulations.

  • These reports explain our assessment of the scientific evidence used to lead to regulatory decisions on the safety of medicines or medicines classes.

  • A digital platform designed to facilitate the reporting, monitoring, and management of medical device incidents.

  • Patient factsheet providing information on respiratory syncytial virus (RSV) and RSV vaccination.

  • Detailed guidance on advertising and promoting medicines.

  • Information about medical devices that the public can buy for personal use and how we make sure they are safe and effective.

  • Details of how Marketing Authorisation Holders can provide information on planned or potential future submissions, to the MHRA.

  • This document provides guidance on the data integrity expectations that should be considered by organisations involved in any aspect of the pharmaceutical lifecycle or GLP studies regulated by MHRA.

  • An overview of the systems and processes DHSC and NHS England use for responding to medicine shortages.

  • You must include the appropriate legal basis for your application when you apply to MHRA for a marketing authorisation.

  • Guide for marketing authorisation holders, including qualified person responsible for pharmacovigilance (PV) and pharmacovigilance system master files (PSMF).

  • Guidance for Applicants wishing to apply for a Promising Innovative Medicines designation, pre-submission meeting or an EAMS Scientific Opinion.

  • Who can supply or administer medicines to patients without a doctor under a PGD, which medicines they can supply, and legal requirements for PGDs.

  • Directory of current ICH Guidelines which have been implemented by the Medicines and Healthcare products Regulatory Agency.

  • Keep up to date with the latest information from the UK GLP monitoring authority.

  • Fees payable to the MHRA from 2025.