Guidance

Mpox (monkeypox) vaccination recommendations

Recommendations for the use of pre- and post-exposure vaccination during an mpox incident.

This publication was withdrawn on

This publication was withdrawn as it is now out of date. Please find the updated information on the page Smallpox and mpox: the green book, chapter 29 (https://www.gov.uk/government/publications/smallpox-and-vaccinia-the-green-book-chapter-29).

Applies to England

Documents

[Withdrawn] Recommendations for the use of pre and post exposure vaccination during an mpox incident

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Details

This document includes information on:

  • pre-exposure vaccination for occupational exposure
  • post-exposure vaccination
  • vaccine prescribing and administration
  • consent and record forms
  • Imvanex® patient information leaflet

Further mpox guidance is also available, including information on case definitions and contact tracing.

Updates to this page

Published 20 May 2022
Last updated 20 November 2024 + show all updates
  1. Guidance withdrawn.

  2. Added version 12, removed appendices 2 to 5.

  3. Updated to include the use of intradermal administration for pre and post-exposure use in healthy adults, limiting post-exposure vaccination to children under 5 and immunosuppressed individuals, during periods of limited supply, and further clarification on vaccine eligibility for occupational exposure.

  4. Updated guidance, version 10.

  5. Version 9: updated background and added a link to classification of contacts (appendix 6), along with advice for vaccination and follow-up.

  6. Updated appendix 6 to clarify recommendations for PEP after 14 days since last exposure.

  7. Updated guidance, version 7.

  8. Updated guidance, version 6.7.

  9. Added links to additional monkeypox guidance.

  10. First published.

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