Non-tech. summaries 2014: projects on other basic research
Projects granted during 2014 that have a primary purpose of other basic research: sensory organs (skin, eyes and ears), forensic enquiries and other research.
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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research: sensory organs (skin, eyes and ears), forensic enquiries and other research.
The following projects were granted:
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genetics and biology of parasitic nematodes (parasitic nematodes, rodents)
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Notch-Wnt interaction in embryonic development (Notch, Wnt, endocytosis, pluripotency, stem cells)
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malaria parasite development and drug discovery (plasmodium, malaria, genetics, antimalarial, mosquito)
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centrosome biology in mammalian development, ageing and stem cell function (development, stem cells, ageing, cell division)
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production and maintenance of GA rodents (production, maintenance, genetically altered rodents)
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generation of transgenic mice for gene manipulation (transgenic, gene targeting, knockout, embryonic stem cells)
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re-derivation of mouse strains (re-derivation; superovulation; embryo transfer)
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identification of immunological targets for developing new agents to prevent corneal transplant rejection (immunological, agents, corneal, transplant, rejection)
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mechanisms of movement generation and inhibition (motor cortex, mirror neurons, movement inhibition, subthalamic nucleus, hyperdirect pathway)
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responses to centrifuge-induced hypergravity (mouse, biomechanics, posture, gait; locomotion)
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pharmacokinetics and metabolism studies (metabolism, pharmacokinetics, regulatory, ADME, non-clinical)
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technical development of preclinical imaging (imaging, non-invasive, quantitative, longitudinal)
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doping/medication control for British horseracing (anti-doping, medication, equine, detection time, control)
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neuroimmune interactions (cytokine, brain, liver, microglia, astrocyte)
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anti-angiogenics in retinal neovascularisation and neuroprotection (retina, angiogenesis, neuroprotection)
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object recognition by zebrafish visual system (zebrafish, vision, in vivo imaging, classical conditioning)
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understanding and manipulating proteostasis (neurodegeneration, chaperone, blindness, virus, stem cell)
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regulation of inflammation in wound repair (chronic wounds, inflammation, diabetes)
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developing therapies for inner ear disorders (hearing, deafness, balance)
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vocal and social learning of avian calls (learning, vocalisation, mobbing, birds)
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eye lens shape and form (eye lens cataract accommodation, radiosensitivity)