Non-tech. summaries 2014: projects on the endocrine system
Projects granted during 2014 that have a primary purpose of basic research into the endocrine system and metabolism.
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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of basic research: endocrine system and metabolism.
The following projects were granted:
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regulation of pituitary physiology (pituitary, gene regulation, prolactin)
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genetics of metabolism (diabetes, obesity, diabetic complications, ageing)
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the aetiology of metabolic disorders (diabetes, obesity, insulin secretion, channelopathy)
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islet pretreatment to reduce hypoxic graft damage (diabetes, islets, transplantation, hypoxia)
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oral delivery of test agents (oral gavage, diabetes therapy)
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neuroplasticity, immunity and behaviour (rodent, seasonality, leukocytes, reproduction, neuroangiogenesis)
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metabolic alterations of pregnancy (pregnancy, metabolic disease, offspring, therapies)
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modulation of endocrine pathways by imprinted genes (Imprinting, hormones, development, epigenetics, metabolic)
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relationship between diabetes and cancer (diabetes, cancer, pancreatitis)
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energy homeostasis and metabolism (food intake, energy expenditure, obesity)
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effects of mitochondrial functioning on mammal phenotype (endothermy, BAT, oxidative stress, rodents)
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nuclear envelope roles in health and disease (nuclear envelope, genorne organ isation, metabolism 5 years)
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the role of copper in diabetes and ageing (arteries, kidney, heart, eyes, biomarkers, treatment)
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the role of NPPC in pituitary development (C-type natriuretic peptide (CNP), genetic modification tissue specific, mouse)
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genetic toxicology: chemicals (mutagen, genetic toxicology)
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impact of gut microbiota on type II diabetes (microbiota, metabolism, type II diabetes, obesity)