Transparency data

Non-tech summaries 2016: projects on oncology

Projects granted during 2016 that have a primary purpose of basic research, oncology.

• From: Home Office
• Published: 22 December 2017

Documents

Non-technical summaries: projects granted in 2016, volume 1

PDF, 538 KB, 58 pages

This file may not be suitable for users of assistive technology.

Request an accessible format.

If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email alternativeformats@homeoffice.gov.uk. Please tell us what format you need. It will help us if you say what assistive technology you use.

Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of basic research, oncology.

The following projects were granted:

• renal cell carcinoma pathogenesis (renal cancer, genetics, carcinogenesis)

• centrosomes in development and cancer (centrosome, chromosome heritance, cilia disease, microcephaly, cancer)

• preclinical models of brain tumours (brain tumours, brain metastases, glioma)

• production and supply of biological products (tissues, monoclonal / polyclonal antibodies, macrophages)

• role of cell cycle regulators in gene regulation (cell division, gene regulation, cells)

• cancer and the micro-environment (cancer, leukaemia, myeloma, micro-environment)

• epithelial stem cell plasticity; relevance to cancer (epithelium, plasticity, stem cells, progenitor cells, cancer)

• investigating ubiquitin ligases in disease. (cancer, neurodegenerative disease, protein degradation)

• understanding mechanisms that regulate tumourigenesis and metastasis (mouse, cancer, metastasis, immune system)

• cell motility and tumour progression (cancer, metastasis, embryonic development)

• studying the host response to tumour and metestasis (cancer – host interaction)

• analysis of skin carcinogenesis in transgenic mice (carcinogenesis, skin, transgenic, mechanism)

• image studies of cancer (tumour, imaging, therapy)

• metabolism as a novel target for cancer therapy (cancer, metabolism)

• targeting the mechanistic drivers of lung tumour progression (tumour progression, therapy, lung cancer)

Published 22 December 2017