vCJD and transfusion of blood components: updated risk assessment
Paper on the transmission of variant vCJD from person to person though receipt of donated blood components.
Applies to England
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This risk assessment presents a mathematical model, primarily designed to examine how many future clinical cases might be caused in this way.
Key inputs to the model include the number of donors that might be carrying Creutzfeldt-Jakob Disease (vCJD) infection without showing any symptoms, the infective dose in blood components sourced from such a donor and the likelihood of recipients surviving long enough to develop symptoms of vCJD if infected.