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Medicines, medical devices

Guidance and regulation

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  • Consumer advice and details of how to report problems with e-cigarettes with guidance on how to place an e-cigarette on the market in Great Britain and Northern Ireland, including the notification scheme.

  • Fees payable to the MHRA from 2025.

  • Guidance on the process for ending a clinical trial.

  • By streamlining decision-making, the MHRA–NICE aligned pathway will help patients access new medicines 3–6 months sooner.

  • How the MHRA makes decisions on whether a borderline product is a medical device and which risk class should apply.

  • This document provides guidance on the data integrity expectations that should be considered by organisations involved in any aspect of the pharmaceutical lifecycle or GLP studies regulated by MHRA.

  • How to make a payment by credit or debit card or a bank transfer for all applications except Device Registration and Certificates of Free Sale applications.

  • How the MHRA processes variations to medicines' marketing authorisations for the UK and Northern Ireland.

  • Guide for marketing authorisation holders, including qualified person responsible for pharmacovigilance (PV) and pharmacovigilance system master files (PSMF).

  • Keep up to date with the latest information from the UK GLP monitoring authority.

  • Take care when using creams to treat dry skin conditions as they can easily dry onto clothing, bedding and bandages, making them more flammable.

  • Guidance for Applicants wishing to apply for a Promising Innovative Medicines designation, pre-submission meeting or an EAMS Scientific Opinion.

  • A wholesale dealer in Great Britain may import Qualified Person certified medicines from the European Economic Area if certain checks are made by the ‘Responsible Person (import)’

  • Guidance for UK wholesalers and manufacturers on how to import human medicines including unlicensed medicines, how to apply for a licence and how much it costs.

  • How to carry out the biological safety evaluation, which is required before undertaking a clinical investigation for a medical device.

  • How to make sure that you are providing the statistical data required as part of a clinical investigation of your medical device.

  • How to make sure your clinical investigation will meet the MHRA's requirements for medical devices.

  • Information on the new regulations for the post-market surveillance of medical devices which come into effect on 16 June 2025.

  • A digital platform designed to facilitate the reporting, monitoring, and management of medical device incidents.

  • Clinical trial applications that need expert advice from a specialist group or committee.