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Globally, there has been a very small number of reports of new-onset or aggravation of pre-existing myasthenia gravis with atorvastatin, pravastatin, lovastatin, fluvastatin, simvastatin, rosuvastatin and pitavastatin (single-ingredient and fixed-dose combination products). Advise patients taking statins to be alert to...
The Department has issued guidance on the use of the prescribing Better Care Better Value Indicators, especially in relation to the indicator for statins.
Statins (HMG-CoA reductase inhibitors) are widely used medicines for patients with lipid disorders and in the primary and secondary prevention of heart attack and stroke.
Statement from Medicines and Healthcare products Regulatory Agency on the risks and benefits of statins.
Healthcare professionals should be aware of the updated information so they can discuss it with new and existing patients.
Detailed recommendations for dose restrictions when used with some other drugs as interactions may increase the risk of adverse effects, or reduce the effectiveness of statin treatment.
Statin use may be associated with a level of hyperglycaemia in some patients where formal diabetes care is appropriate.
These reports explain our assessment of the scientific evidence used to lead to regulatory decisions on the safety of medicines or medicines classes.
There is a risk of rhabdomyolysis if Systemic fusidic acid (Fucidin) is given with statins.
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