Down’s syndrome, Edwards’ syndrome and Patau’s syndrome: options after a higher chance screening result
Information for pregnant women with singleton (having only one baby) and twin pregnancies who have received a higher-chance result from the combined or quadruple screening test
Applies to England
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This information should support, but not replace, the discussions pregnant women have with healthcare professionals.
The information is available in 12 other languages: Arabic, Bengali, Chinese, French, Latvian, Lithuanian, Polish, Portuguese, Punjabi, Romanian, Somali and Urdu.
This information is available in A4 PDF format (in English) to print out and provide for people who cannot access digital information (see list above).
Contact the Screening helpdesk with any queries about this publication, making sure you include its full title.
Updates to this page
Published 1 June 2021Last updated 23 April 2024 + show all updates
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Removed references to PHE, and wording now aligned according to Screening tests for you and your baby (STFYAYB). Clarified information on NIPT choices, in particular when women receive a very high chance result (between ‘1 in 2’ and ‘1 in 10’) from the combined or quadruple tests.
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Addition of plain A4 PDF version for printing, to provide for people unable to access this information online.
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Added text description for 'options after higher chance screening result' flowchart.
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Addition of 12 language translations.
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First published.