Non-tech. summaries 2015: projects on human cancer
Projects granted during 2015 that have a primary purpose of translational and applied research: projects on human cancer.
Documents
Details
This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2015 with a primary purpose of translational and applied research: projects on human cancer.
It contains a full list of the 22 projects that were granted.
The projects covered are:
-
imaging and image-guided therapy (in-vivo, imaging, cancer, mouse)
-
functions of dna repair genes in genome stability and cancer (DNA repair, cancer, genome stability)
-
mechanisms of brain cancer progression (brain, CNS, cancer, mouse)
-
novel immuno-oncology therapies (cancer, tumour, immunotherapies)
-
focus on the BRCA1 n-terminus in development and cancer (breast cancer, genetics)
-
imaging in drug discovery (non-invasive, medical imaging, drug discovery)
-
immunotherapy of cancer (immunology, cancer, vaccine, therapy, cure)
-
novel therapies for human cancer (cancer, tumour, drug)
-
RAC and RAC regulators in development and cancer (RAC, cancer initiation, metastasis)
-
evaluation of novel treatments for prostate cancer (prostate, androgen receptor, n-terminal domain, rotenoid)
-
using patient derived xenografts to study cancer (cancer, patient derived xenograft (PDX))
-
function of tetraspan complexes in carcinogenesis (tetraspan, integrin, kinase, tumourigenesis, metastasis)
-
translational chrono-oncology (biological clocks, cancer, pharmacology)
-
identifying and characterising the cellular drivers of adult acute lymphoblastic leukaemia (leukaemia mouse models)
-
investigation of normal and aberrant haemopoiesis (haemopoiesis, cancer, bone marrow failure, graft-versus-host disease)
-
biology of normal and malignant blood cells (leukaemia, cord blood, fusion gene, cytokine)
-
therapeutic antibodies for cancer (monoclonal antibody, immune therapy, cancer)
-
in vivo assessment of biomaterials (cancer therapies)
-
advanced nucleic acid and small molecule therapies for cancers (nucleic, acid, molecule therapies cancers)
-
radiation combinations for cancer treatments (radiation, rodent, cancer)
-
evaluation of therapeutics for the treatment of head and neck cancer (head and neck, thyroid, cancer, drug discovery)
-
therapeutic strategies to improve organ quality and function in a pig model (transplantation, retrieval, improve organ quality)