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Non-tech. summaries 2015: projects on sensory organs

Projects granted during 2015 that have a primary purpose of basic research: sensory organs (skin, eyes and ears).

• From: Home Office
• Published: 24 June 2016

Documents

Non-technical summaries: projects granted in 2015, volume 25

PDF, 404 KB, 53 pages

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Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2015 with a primary purpose of basic research: sensory organs (skin, eyes and ears).

The following projects were granted:

• therapy in mitochondrial optic neuropathy (optic neuropathy, mitochondria, retinal ganglion cells)

• corneal stromal stem cells for corneal regeneration (cornea, amniotic membrane, stem cells, ocular surface, wound healing)

• maximising the success and effects of glaucoma filtration surgery (glaucoma, wound healing, transplant, angiogenesis)

• protection and repair of the retina & optic nerve (glaucoma, macular degeneration, optic nerve)

• novel therapeutic targets in ocular disease (VEGF, diabetes, AMD, neuroprotection, neovascularisation)

• regulation of keratinocyte proliferation and differentiation (skin, mouth, cancer, inflammation, stem cells)

• the contribution of mast cells and their mediators in inflammatory skin diseases (mast cells, psoriasis, atopic dermatitis, allergy)

• protecting and repairing the injured eye (eye, nerves, trauma, neuron, death)

• protecting and repairing injured retinal cells in glaucoma (glaucoma, retinal ganglion cell, trabecular meshwork, scarring)

• the impact of context on rat whisking behaviour (vibrissa, whisking, tactile, attention, neuroethology)

• control of vascular behaviour in the retina (retinal vasculature, angiogenesis, inflammation)

• retinal development and degeneration in zebrafish (zebrafish, retinal degeneration, disease mechanisms, treatment)

• investigating epithelial maintenance, pathogenesis and wound healing (epithelium, stem cell, cancer, infection, wound healing)

• early diagnosis and therapy through the eye (retina, neurodegeneration, neuroprotection, imaging, treatment)

• functions of novel lipids in wounded skin (wound healing, lipids, skin disease)

• novel biologics for treating ocular disease (binding domains, auto-immune eye disease)

Published 24 June 2016