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• Using persistent organic pollutants (POPs)

  Substances that are classed as persistent organic pollutants (POPs) and when you're allowed to use them.

  • Updated: 12 January 2024
• Eplontersen approved to treat adults with rare inherited nerve disease or polyneuropathy

  The Medicines and Healthcare products Regulatory Agency (MHRA) has approved eplontersen (Wainzua) to treat adults with polyneuropathy associated with hereditary transthyretin amyloidosis (ATTRv), which is a rare progressive condition that runs in families caused by a protein called transthyretin (TTR).

  • Updated: 4 April 2025
• Access, new active substance and biosimilar work sharing initiatives

  Information on applying for New Active Substance Work Sharing Initiative (NASWSI) and Biosimilar Work Sharing Initiative (BSWSI) assessments and list of approved products.

  • Updated: 18 February 2025
• Lazertinib approved for use in combination with amivantamab for the treatment of adults with non-small cell lung cancer 

  As with all products, the MHRA will keep its safety under close review.

  • Updated: 6 March 2025
• Nitrous oxide: updated harms assessment (accessible)
  • Updated: 22 June 2023
• Donanemab licensed for early stages of Alzheimer’s disease in adult patients who have one or no copies of apolipoprotein E4 gene

  The Medicines and Healthcare products Regulatory Agency (MHRA) has today, 23 October 2024, approved a licence for the medicine donanemab (Kisunla) for use in the early stages of Alzheimer’s disease, following a thorough review of the benefits and risks.

  • Updated: 23 October 2024
• Pesticide residues in food: glossary
  • Updated: 25 September 2024
• MHRA approves vibegron to treat adult patients with Overactive Bladder Syndrome (OAB)

  The Medicines and Healthcare products Regulatory Agency (MHRA) has today, 17 July 2024, approved the medicine vibegron (Obgemsa) to treat the symptoms of overactive bladder (OAB) syndrome in adults. Symptoms may include a sudden need to empty the bladder...

  • Updated: 17 July 2024
• ACMD advice on 2-benzyl benzimidazole and piperidine benzimidazolone opioids (accessible version)
  • Updated: 29 January 2025
• Producing Irish Whiskey, Irish Cream or Irish Poteen

  Find out about applying for the Spirit Drinks Verification Scheme, how to submit brand information, fees and making sure your production process is compliant.

  • Updated: 1 April 2025