Non-tech summaries 2016: projects on other basic research
Projects granted during 2016 that have a primary purpose of basic research: multisystemic and other.
Documents
Details
This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of basic research: multisystemic and other.
The following projects were granted:
-
development of novel PET and SPECT imaging biomarkers (imaging, PET, SPECT, radiotracer, biomarker)
-
applying genetic engineering to the chicken (chicken, genetic engineering, development, health)
-
analysis of plant ion channel and receptors (SNAREs / K+ channels / cell growth / proliferation)
-
phenotyping genetically altered mice (phenotyping, ageing, genetics, high-throughput)
-
spatial and temporal regulation of dna replication (DNA replication, cell proliferation, chromosome, nucleus)
-
functional analysis of vertebrate enhancers (gene regulation, enhancers, conserved sequences, development)
-
advancing methods for rederiving and archiving genetically altered mice (mouse, freezing, sperm, embryos, technology)
-
molecular genomic and phenotypic analysis of environmental adaptations in cyprinid fish (molecular genomic, phenotypic analysis, environmental adaptations, cyprinid fish)
-
the european xenopus resource centre (european, xenopus, resource, centre)
-
early growth and life-long health (development, growth, genetics, epigenetics, metabolism)
-
investigation of the role of nox and reactive oxygen species in the pathogenesis of cardiovascular and metabolic disorders diseases and their treatment (NADPH oxidase; oxidative stress; cardiovascular diseases; insulin resistance; diabetes)
-
effects of contaminants on fish physiology (fish, metals, contaminants, toxicology, physiology)
-
investigating the (patho)physiological importance of S-acylation (S-acylation, palmitoylation, zDHHC enzymes)
-
improving the pharmacokinetics and tissue targeting of antimicrobials (antimicrobial, melioidosis, burkholderia pseudomallei, francisella tularensis, pharmacokinetics)
-
molecular regulation of mammalian development (genes , oocyte, development)
-
developmental dynamics of tissue formation (developmental biology, spinal cord, central nervous system)
-
role of centrosomes, centrioles and cilia in vertebrate development (centrioles, cilia, vertebrate development)
-
production and maintenance of genetically altered mice (production, geneticall altered, archiving)
-
caveolae and endothelial transcytosis (caveolae, endothelium, blood vessel, endocytosis)
-
deciphering the mechanisms of early embryonic development (vertebrate development, stem cells, xenopus)
-
fungal infection, diagnosis and therapy (fungus, infection, antifungal, therapy, diagnosis)
-
supply of biospecimens from rats and mice (blood, tissues, drug discovery/development)
-
preclinical imaging in biomedical research (PET, imaging, drug)
-
understanding mechanisms of fibrosis (fibrosis, scar, myofibroblasts, therapy, diagnosis)